Alternatives to Opioids in the Pharmacologic Management ...
Tanezumab showed superior pain relief over naproxen and placebo in CLBP studies. BoNT-A injections provided better pain relief than saline in CLBP. Lidocaine patches showed no significant efficacy over placebo for CLBP. Tramadol and tapentadol were effective for CLBP, with some studies showing superiority over placebo. Muscle relaxants like carisoprodol and cyclobenzaprine offered better pain relief than placebo in CLBP. Antidepressants, including TCAs and SNRIs, were effective for CLBP pain relief. NSAIDs were superior to placebo for CLBP in several studies. Gabapentin and pregabalin showed efficacy in reducing pain intensity in CLBP and FM. Capsaicin patches provided modest pain relief in PHN. TCAs and SNRIs were effective in reducing pain intensity in PHN and PDN. Ketamine showed short-term pain relief in CRPS. IVIG and bisphosphonates were effective in CRPS pain management.
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Tanezumab showed superior pain relief over naproxen and placebo in CLBP studies. BoNT-A injections provided better pain relief than saline in CLBP. Lidocaine patches showed no significant efficacy over placebo for CLBP. Tramadol and tapentadol were effective for CLBP, with some studies showing superiority over placebo. Muscle relaxants like carisoprodol and cyclobenzaprine offered better pain relief than placebo in CLBP. Antidepressants, including TCAs and SNRIs, were effective for CLBP pain relief. NSAIDs were superior to placebo for CLBP in several studies. Gabapentin and pregabalin showed efficacy in reducing pain intensity in CLBP and FM. Capsaicin patches provided modest pain relief in PHN. TCAs and SNRIs were effective in reducing pain intensity in PHN and PDN. Ketamine showed short-term pain relief in CRPS. IVIG and bisphosphonates were effective in CRPS pain management.