Tranexamic acid's efficacy in liver resection is under scrutiny in the HeLiX trial, a multicenter, placebo-controlled study. Led by Dr. Paul Karanicolas of the University of Toronto, the trial seeks to determine whether tranexamic acid can improve patient outcomes following liver resection. The results will be presented at the PCT Grand Rounds on November 22, 2024.
Dr. Karanicolas, a professor of surgery at the University of Toronto and the Sherif and Mary-Lou Hanna Chair in Surgical Oncology Research, designed the HeLiX trial as a pragmatic clinical trial. This approach aims to evaluate the real-world effectiveness of tranexamic acid in a broad patient population undergoing liver resection.
The HeLiX trial is a randomized, placebo-controlled study, ensuring a rigorous comparison between patients receiving tranexamic acid and those receiving a placebo. The trial's primary endpoint is focused on assessing the impact of tranexamic acid on outcomes relevant to liver resection patients.
Liver resection is a complex surgical procedure, and improving patient outcomes is a critical goal. The HeLiX trial's findings could provide valuable insights into the role of tranexamic acid in optimizing care for individuals undergoing this surgery. The presentation at the PCT Grand Rounds will offer a detailed analysis of the trial's results and their implications for clinical practice.