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Tenax Therapeutics Secures $25M Private Placement to Advance Phase 3 Cardiopulmonary Trials

• Tenax Therapeutics has secured a $25 million private placement from RTW Investments to fund ongoing and planned Phase 3 clinical trials for novel cardiopulmonary therapies.

• The financing includes 378,346 shares of common stock and pre-funded warrants for 3,760,726 shares, with Leerink Partners leading the placement alongside Guggenheim Securities and William Blair.

• The strategic investment will strengthen Tenax's position in developing innovative cardiopulmonary treatments, with proceeds directed towards clinical advancement and general corporate operations.

Tenax Therapeutics, a Chapel Hill-based pharmaceutical company focused on developing novel cardiopulmonary therapies, has secured a significant financial boost through a $25 million private placement with RTW Investments. The agreement, announced on March 5, 2025, marks a crucial step forward in advancing the company's Phase 3 clinical development programs.

Investment Structure and Terms

The private placement comprises 378,346 shares of common stock priced at $6.04 per share and pre-funded warrants for an additional 3,760,726 shares at $6.03 each. The warrants, which carry a nominal exercise price of $0.01, have been structured with no expiration date, offering long-term flexibility for investors. Leerink Partners is spearheading the placement as the lead agent, supported by Guggenheim Securities and William Blair as joint placement agents.

Strategic Allocation of Funds

The capital injection comes at a critical juncture for Tenax Therapeutics' development pipeline. The company has earmarked the net proceeds primarily for:
  • Advancement of ongoing Phase 3 clinical trials
  • Initiation of planned Phase 3 studies
  • Working capital requirements
  • Capital expenditures
  • General corporate operations

Regulatory Compliance and Securities Details

The private placement is being conducted under Section 4(a)(2) of the Securities Act of 1933 and Regulation D. While the issued securities are not currently registered under the Securities Act, Tenax has committed to filing a registration statement with the SEC within 45 days of the placement's closing. This registration will cover the resale of both the common stock shares and the shares issuable through the pre-funded warrants.

Market Impact and Future Outlook

This substantial funding reinforces Tenax Therapeutics' position in the cardiopulmonary therapeutic space and provides the financial runway needed to advance its late-stage clinical programs. The investment by RTW Investments, a respected healthcare-focused investment firm, signals strong confidence in Tenax's development pipeline and strategic direction.
The transaction is expected to conclude on March 5, 2025, subject to standard closing conditions. This financing round strengthens Tenax's ability to pursue its clinical development goals while maintaining operational flexibility in its pursuit of novel cardiopulmonary treatments.
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