JOHNS HOPKINS UNIVERSITY
Clinical Trials
1.7k
Trial Phases
6 Phases
Drug Approvals
0
Drug Approvals
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Clinical Trials
Distribution across different clinical trial phases (1480 trials with phase data)• Click on a phase to view related trials
HomeLink2: Reducing Posthospitalization Mortality Through Structured Home Care and Nutritional Support
- Conditions
- HIV
- First Posted Date
- 2025-08-05
- Last Posted Date
- 2025-08-05
- Lead Sponsor
- Johns Hopkins University
- Target Recruit Count
- 780
- Registration Number
- NCT07102745
- Locations
- 🇿🇦
Tshepong Hospital, Klerksdorp, North West Province, South Africa
Feasibility and Tolerability of IMLYGIC for the Treatment of Cutaneous Neurofibromas in Adults With NF1
- Conditions
- NF1NeurofibromatosisCutaneous Neurofibroma
- Interventions
- First Posted Date
- 2025-08-03
- Last Posted Date
- 2025-08-03
- Lead Sponsor
- Johns Hopkins University
- Target Recruit Count
- 10
- Registration Number
- NCT07102394
- Locations
- 🇺🇸
Johns Hopkins University, Baltimore, Maryland, United States
3D Printed Occlusal Splints for Intraoperative Use
- Conditions
- Malocclusion, Angle Class IMalocclusion, Angle Class IIMalocclusion, Angle Class III
- First Posted Date
- 2025-07-22
- Last Posted Date
- 2025-07-22
- Lead Sponsor
- Johns Hopkins University
- Target Recruit Count
- 70
- Registration Number
- NCT07079111
Investigating the Safety and Efficacy of the 1927-nm Thulium Laser in Keratosis Pilaris
- Conditions
- Keratosis Pilaris (KP)
- First Posted Date
- 2025-07-22
- Last Posted Date
- 2025-07-22
- Lead Sponsor
- Johns Hopkins University
- Target Recruit Count
- 25
- Registration Number
- NCT07078461
- Locations
- 🇺🇸
Johns Hopkins University, Baltimore, Maryland, United States
18F-FAPI-74 in Tuberculosis Patients
- Conditions
- Tuberculosis, Pulmonary
- First Posted Date
- 2025-07-22
- Last Posted Date
- 2025-08-03
- Lead Sponsor
- Johns Hopkins University
- Target Recruit Count
- 30
- Registration Number
- NCT07077213
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News
Precision BioSciences Reports First Clinical Evidence of Hepatitis B Gene Editing Therapy PBGENE-HBV
Precision BioSciences' PBGENE-HBV demonstrated substantial antiviral activity in all three patients in the lowest dose cohort, achieving 47-69% reductions in hepatitis B surface antigen levels.
BMJ Investigation Uncovers Data Integrity Issues in AstraZeneca's Ticagrelor Heart Drug Trials
A BMJ investigation has revealed evidence of serious misreporting in two clinical trials that were pivotal to ticagrelor's approval by the FDA and UK regulators.
Infinity Bio Secures $8M Series A to Advance Antibody Reactome Profiling Technology
Infinity Bio closed an $8 million Series A financing round led by Illumina Ventures to expand its proprietary MIPSA™ antibody reactome profiling platform.
Innocan Pharma Advances Liposomal CBD Platform for Chronic Pain as Peer-Reviewed Study Highlights Non-Opioid Alternative
A peer-reviewed narrative review published in Cureus journal highlights the therapeutic potential of long-acting synthetic cannabidiol (CBD) for chronic pain management as a non-opioid alternative.
Neoadjuvant Nivolumab Plus Chemotherapy Demonstrates 10% Survival Advantage in Resectable NSCLC at 5-Year Follow-up
The CheckMate 816 phase 3 trial demonstrates that patients with resectable non-small cell lung cancer who received nivolumab plus chemotherapy before surgery had approximately 10% higher survival rates at 5 years compared to chemotherapy alone.
Lantern Pharma's LP-184 Demonstrates Significant Survival Benefits in Pediatric Brain Cancer Models
LP-184 showed remarkable survival improvements in mouse models of atypical teratoid rhabdoid tumors (ATRT), with median survival increasing by 345% in one model (p<0.0001).
Maryland Stem Cell Research Fund Allocates $18 Million to Advance Regenerative Medicine Research
The Maryland Stem Cell Research Commission has awarded over $18 million in grants to 52 investigators working on nearly 50 different medical conditions including sickle cell anemia, diabetes, and various neurological disorders.
Responsive Parenting and Digital Support Significantly Reduce Childhood Obesity Risk, Studies Show
Responsive parenting techniques implemented during infancy and toddlerhood led to significantly lower BMI in children through middle childhood, with particularly strong benefits observed in girls.
GLP-1 Drug Use Surges Among Type 1 Diabetes Patients Despite Safety Concerns
GLP-1 receptor agonist use has increased dramatically among type 1 diabetes patients, with prescriptions rising from 4% to 33% in severely obese adults over the past decade.
Higher-Dose Fractionated Reirradiation Shows Promise in Recurrent High-Grade Glioma Treatment
A Johns Hopkins study of 230 patients demonstrates fractionated reirradiation is safe and effective for recurrent high-grade glioma, with median overall survival reaching 10.2 months from treatment initiation.