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BioAtla

BioAtla logo
🇺🇸United States
Ownership
Public
Established
2007-01-01
Employees
65
Market Cap
$86.5M
Website
http://www.bioatla.com
Introduction

BioAtla, Inc. engages in the development of novel class of specific and selective antibody-based therapeutics for the treatment of solid tumor cancer. Its CAB portfolio include MABs & ADCS, BA3011, and BA3021. The company was founded by Jay M. Short and Carolyn Anderson in March 2007 and is headquartered in San Diego, CA.

Clinical Trials

9

Active:6
Completed:1

Trial Phases

2 Phases

Phase 1:7
Phase 2:2

Drug Approvals

0

Drug Approvals

No drug approvals found

This company may not have drug approvals in our database

Clinical Trials

Distribution across different clinical trial phases (9 trials with phase data)• Click on a phase to view related trials

Phase 1
7 (77.8%)
Phase 2
2 (22.2%)

Phase 1 Study Evaluating BA3182 in Patients With Advanced Adenocarcinoma.

Phase 1
Recruiting
Conditions
Advanced Adenocarcinoma
Interventions
First Posted Date
2023-04-11
Last Posted Date
2025-06-15
Lead Sponsor
BioAtla, Inc.
Target Recruit Count
168
Registration Number
NCT05808634
Locations
🇺🇸

UC Irvine, Irvine, California, United States

🇺🇸

Northwestern University, Chicago, Illinois, United States

🇺🇸

Karmanos Cancer Institute, Detroit, Michigan, United States

and more 6 locations

A Phase 2 Open Label Study of BA3021 in Patients With Recurrent or Metastatic Squamous Cell Carcinoma of the Head and Neck

Phase 2
Recruiting
Conditions
Metastatic Cancer
Head and Neck Cancer
Squamous Cell Carcinoma of Head and Neck
Metastatic Squamous Cell Carcinoma of the Head and Neck
Recurrent Squamous Cell Carcinoma of the Head and Neck
Interventions
First Posted Date
2022-03-09
Last Posted Date
2023-09-29
Lead Sponsor
BioAtla, Inc.
Target Recruit Count
80
Registration Number
NCT05271604
Locations
🇺🇸

USC Norris Comprehensive Cancer Center, Los Angeles, California, United States

🇺🇸

Christiana Care Helen Graham Cancer Center, Newark, Delaware, United States

🇺🇸

Northwestern University, Chicago, Illinois, United States

and more 5 locations

A Phase 1/2 Study of BA3071 as Monotherapy and in Combination With a PD-1 Blocking Antibody (Currently Enrolling Patients With Nonsquamous or Recurrent NSCLC (Type IIB, IIIA, IV)

Phase 1
Active, not recruiting
Conditions
Melanoma
NSCLC
Interventions
First Posted Date
2022-01-06
Last Posted Date
2025-06-15
Lead Sponsor
BioAtla, Inc.
Target Recruit Count
320
Registration Number
NCT05180799
Locations
🇺🇸

The Angeles Clinic and Research Institute, Los Angeles, California, United States

🇺🇸

USC Norris Comprehensive Cancer Center, Los Angeles, California, United States

🇺🇸

Piedmont West, Atlanta, Georgia, United States

and more 9 locations

CAB-AXL-ADC Safety and Efficacy Study in Adults with NSCLC

Phase 2
Active, not recruiting
Conditions
Non-Small-Cell Lung Cancer
Interventions
Biological: PD-1 inhibitor
First Posted Date
2020-12-23
Last Posted Date
2025-01-13
Lead Sponsor
BioAtla, Inc.
Target Recruit Count
240
Registration Number
NCT04681131
Locations
🇺🇸

City of Hope - Duarte, Duarte, California, United States

🇺🇸

University of California Irvine Medical Center (UCIMC) - Chao Family Comprehensive Cancer Center, Irvine, California, United States

🇺🇸

California Research Institute, Los angeles, California, United States

and more 56 locations

CAB-ROR2-ADC Safety and Efficacy Study in Patients With TNBC or Head & Neck Cancer (Ph1) and NSCLC or Melanoma (Ph2)

Phase 1
Completed
Conditions
Melanoma
Head and Neck Cancer
Non Small Cell Lung Cancer
Triple Negative Breast Cancer
Interventions
Biological: PD-1 inhibitor
First Posted Date
2018-04-20
Last Posted Date
2025-01-15
Lead Sponsor
BioAtla, Inc.
Target Recruit Count
132
Registration Number
NCT03504488
Locations
🇺🇸

University of Arizona Cancer Center, Tucson, Arizona, United States

🇺🇸

City of Hope - Duarte, Duarte, California, United States

🇺🇸

University of California, San Diego (UCSD) - Moores Cancer Center, La Jolla, California, United States

and more 55 locations
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News

BioAtla's BA3182 Shows Tumor Shrinkage Across Multiple Cancer Types in Phase 1 Trial

BioAtla presented first-in-human Phase 1 data for BA3182, a dual-conditionally active bispecific T-cell engager targeting EpCAM and CD3, showing tumor reductions in five patients across different adenocarcinoma types.

BioAtla's Tab-cel Shows Promise in Refractory Head and Neck Cancer

BioAtla's Tab-cel demonstrated an overall response rate in heavily pretreated head and neck cancer patients, with 11 responses out of 29 evaluable patients.

BioAtla Highlights Promising Clinical Data and Financial Results in Q3 2024

BioAtla's ozuriftamab vedotin Phase 2 trial shows a 9-month median overall survival in heavily pretreated head and neck cancer patients, indicating potential efficacy.

Context Therapeutics Acquires Rights to BioAtla's Nectin-4 x CD3 TCE, BA3362, for up to $133 Million

Context Therapeutics has acquired the exclusive worldwide license to BioAtla's BA3362, a Nectin-4 x CD3 T-cell engager (TCE), for up to $133 million, including upfront and milestone payments.

BioAtla's Evalstotug (BA3071) Shows Promise in Advanced Solid Tumors

BioAtla's evalstotug (BA3071), a conditionally active anti-CTLA-4 biologic, demonstrates potential in treating advanced solid tumors, with updated Phase 1 study results to be presented at SITC 2024.

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