Unicef

Merck announces new HPV vaccine data to be presented at IPVC 2024, highlighting the importance of vaccination for both females and males to prevent HPV-related cancers and diseases.

WHO and Africa CDC experts met in Brazzaville to guide countries in developing targeted mpox vaccine plans, emphasizing local epidemiology and efficient use of limited doses. 17 countries and partners participated, focusing on tools and recommendations for vaccination strategies. Despite supply constraints, 280,000 doses were delivered to 3 African countries, with over 50,000 doses administered. Collaboration aims to control mpox through vaccination, diagnostics, and community engagement.

Mpox cases in Congo appear to be stabilizing, with weekly lab-confirmed cases dropping from nearly 400 in July to 200-300. However, only 40-50% of suspected infections are tested, and vaccine distribution remains insufficient. WHO estimates only 50,000 of Congo's 110 million population have been immunized. The Africa CDC estimates 3 million vaccines are needed for Congo and 7 million for the rest of Africa. Despite initial vaccine deliveries, concerns remain about the virus's spread and higher death rate compared to the 2022 outbreak.

An attack on a primary health care center in northern Gaza injured six, including four children, during a polio vaccination campaign. WHO Director-General Tedros Adhanom Ghebreyesus called the incident concerning, while the IDF denied responsibility. The campaign aims to vaccinate 119,000 children but faces challenges due to security restrictions.

Join the Education Collaboratory at Yale on Nov 20, 2024, to celebrate the 65th anniversary of the Declaration of the Rights of the Child and the 35th anniversary of the Convention on the Rights of the Child. The event, co-hosted with Yale’s UNICEF chapter, focuses on SEL as a human right, featuring an interactive SEL experience and dialogue on youth mental health and climate change. Advanced registration is requested by Nov 13, 2024. Event details: Nov 20, 2024, 10:00 AM – 12:00 PM, 230 South Frontage, New Haven, CT, Cohen Auditorium.

Sanofi reports 15.7% Q3 sales growth, driven by vaccine sales and strong business performance, raising 2024 EPS guidance. Dupixent sales up 23.8%, with full-year target confirmed at €13 billion. Pharma launches grew 67.1%, led by ALTUVIIIO, Nexviazyme, and Rezurock. Vaccines sales increased 25.5%, boosted by flu sales and Beyfortus. Opella sales rose 7.9%, supported by Qunol acquisition. R&D expenses grew 12.7%, while SG&A expenses grew 6.4%. Business EPS at €2.86, up 12.2% reported and 17.6% at CER. Four regulatory approvals and four positive phase 3 data readouts achieved. Negotiations underway to transfer a controlling stake of Opella to CD&R. 2024 business EPS guidance upgraded to low single-digit growth at CER.

SLS Europe and Bilthoven Biologicals receive positive CHMP Opinion for SIILTIBCY®, a novel Tuberculosis Skin Test in Europe, with EMA's final decision on marketing approval expected by end of 2024.

MVA-BN vaccine showed similar immune response in adolescents and adults with no safety issues in a U.S. phase 2 trial. The vaccine, marketed as Jynneos in the U.S. and Imvanex in Europe, is now approved for adolescents. The WHO has prequalified the vaccine for use in high-risk groups, including infants and pregnant women. Bavarian Nordic plans to trial the vaccine in children aged 2 to 12, and CEPI is funding studies on post-exposure vaccination efficacy.

Shri JP Nadda inaugurated the 19th International Conference of Drug Regulatory Authorities (ICDRA) in India, emphasizing India's role as the 'Pharmacy of the World' and its commitment to global health. The event, hosted by CDSCO in partnership with WHO, aims to foster international collaboration among regulatory bodies. Key discussions include smart regulation, medical devices, AI in healthcare, and post-COVID preparedness. India's pharmaceutical industry, highlighted at the event, is the 4th largest export sector globally.

Barrister Sultan Bajwa announced 77% completion of water supply projects with JICA, benefiting 200,000 people. FDA and Wasa projects near completion. Surface Water Treatment Plant Phase I inspected. Punjab CM warns price control magistrates. Hero Award ceremony for teachers held.