Unicef

Bavarian Nordic commits to donate 15,000 doses of MVA-BN mpox vaccine to Africa, with Emergency Use Authorization granted in DR Congo. The vaccine, approved by FDA and EMA, aims to combat the rising mpox outbreak in Africa, where over 9,000 cases and 400 deaths have been reported in 2024.

WHO prequalifies MVA-BN vaccine from Bavarian Nordic, accelerating access in Africa to combat mpox. Recommended for adults in two doses, 4 weeks apart, with 82% effectiveness. Urgent scale-up in procurement and distribution needed for equitable access.

Mpox continues to spread in DRC and Burundi, with focus on vaccines, drugs, improved care, diagnostics, and public health messaging to control the outbreak. Existing smallpox vaccines provide cross-protection, and new mpox-specific vaccines are in development. Antiviral drugs are being tested, and improved care in clinical trials reduced fatality rates. Rapid and point-of-care diagnostics are needed. Public health messaging must address misinformation and low awareness.

UNAIDS welcomes Gilead Science's voluntary licensing of long-acting HIV drug lenacapavir for generic production but urges transparency on pricing and inclusion of all low and middle-income countries. UNAIDS highlights the potential of lenacapavir to reduce new HIV infections, especially among vulnerable groups, and calls for its accessibility in high-HIV-rate African countries.

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Bavarian Nordic A/S announced an agreement with UNICEF to supply 1 million doses of the MVA-BN mpox vaccine for Africa, with all doses available by end of 2024.

President Biden pledges $500 million and 1 million mpox vaccine doses for Africa, urging global partners to match the commitment to reach $1 billion. The U.S. has led global mpox response efforts, including vaccine donations, clinical care support, and multilateral partnerships with WHO, Africa CDC, and Gavi.

A new $150 million partnership aims to end childhood lead poisoning by 2040, with UNICEF and USAID leading efforts to phase out lead from everyday products and enforce safe standards. The initiative reflects the belief that educators and leaders must give as much as they can to solve problems and ensure children reach their full potential.

Canada pledges CAN $151 million over 3 years to Global Polio Eradication Initiative, bringing total contributions to over CAN $1 billion since 1988. This funding supports immunizing 370 million children annually and bolsters health infrastructure in vulnerable regions, aiming to eradicate polio globally.

EMA recommends Novo Nordisk's Wegovy for heart failure in obese individuals, expanding its use beyond weight loss. FDA approves Zevra Therapeutics' drug for a rare genetic disorder and AstraZeneca's nasal spray flu vaccine. FTC sues top U.S. pharmacy benefit managers over insulin price inflation. UNICEF stresses stigma combat in Burundi's mpox outbreak.