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Editas Medicine

Editas Medicine logo
🇺🇸United States
Ownership
Public
Established
2013-01-01
Employees
265
Market Cap
$315M
Website
http://www.editasmedicine.com
Introduction

Editas Medicine, Inc. engages in the development and commercialization of genome editing technology. Its technology includes clustered, regularly interspaced short palindromic repeats (CRISPR), and CRISPR associated protein 9 (Cas9). The company was founded by Feng Zhang, Jennifer A. Doudna, George McDonald Church, J. Keith Joung and David R. Liu in September 2013 and is headquartered in Cambridge, MA.

A Long-Term Follow-Up Study of Participants With Sickle Cell Disease or Transfusion Dependent β-Thalassemia Who Received EDIT-301

Conditions
Hemoglobinopathies
Sickle Cell Disease
Transfusion-dependent Beta-Thalassemia
Interventions
Other: Safety and efficacy assessments
First Posted Date
2024-04-12
Last Posted Date
2025-04-02
Lead Sponsor
Editas Medicine, Inc.
Target Recruit Count
54
Registration Number
NCT06363760
Locations
🇺🇸

Smilow Cancer Hospital, New Haven, Connecticut, United States

🇺🇸

Johns Hopkins All Children's Hospital, Saint Petersburg, Florida, United States

🇺🇸

Children's Healthcare of Atlanta, Atlanta, Georgia, United States

and more 15 locations

EDIT-301 for Autologous Hematopoietic Stem Cell Transplant (HSCT) in Participants With Transfusion-Dependent Beta Thalassemia (TDT)

Phase 1
Active, not recruiting
Conditions
Hemoglobinopathies
Transfusion Dependent Beta Thalassemia
Thalassemia Intermedia
Thalassemia Major
Interventions
Genetic: EDIT-301
First Posted Date
2022-07-06
Last Posted Date
2025-04-02
Lead Sponsor
Editas Medicine, Inc.
Target Recruit Count
9
Registration Number
NCT05444894
Locations
🇺🇸

University of California San Francisco, Oakland, California, United States

🇺🇸

University of Minnesota, Minneapolis, Minnesota, United States

🇺🇸

Columbia University Medical Center, New York, New York, United States

and more 5 locations

A Study Evaluating the Safety and Efficacy of EDIT-301 in Participants With Severe Sickle Cell Disease (RUBY)

Phase 1
Active, not recruiting
Conditions
Hemoglobinopathies
Sickle Cell Disease
Interventions
Genetic: EDIT-301
First Posted Date
2021-04-21
Last Posted Date
2025-01-31
Lead Sponsor
Editas Medicine, Inc.
Target Recruit Count
45
Registration Number
NCT04853576
Locations
🇺🇸

UCSF Benioff Children's Hospital, Oakland, California, United States

🇺🇸

Children's Hospital Colorado, Aurora, Colorado, United States

🇺🇸

Smilow Cancer Hospital, New Haven, Connecticut, United States

and more 21 locations

Single Ascending Dose Study in Participants With LCA10

Phase 1
Active, not recruiting
Conditions
Leber Congenital Amaurosis 10
Inherited Retinal Dystrophies
Eye Diseases, Hereditary
Retinal Disease
Vision Disorders
Retinal Degeneration
Eye Disorders Congenital
Interventions
First Posted Date
2019-03-13
Last Posted Date
2022-12-05
Lead Sponsor
Editas Medicine, Inc.
Target Recruit Count
34
Registration Number
NCT03872479
Locations
🇺🇸

Bascom Palmer Eye Institute, Miami, Florida, United States

🇺🇸

Massachusetts Eye and Ear Infirmary, Boston, Massachusetts, United States

🇺🇸

W.K. Kellogg Eye Center - University of Michigan, Ann Arbor, Michigan, United States

and more 2 locations

Natural History Study of CEP290-Related Retinal Degeneration

Completed
Conditions
Vision Disorders
Eye Diseases, Hereditary
Retinal Disease
Leber Congenital Amaurosis 10
Eye Diseases
Retinal Degeneration
Blindness
Eye Disorders Congenital
First Posted Date
2018-01-10
Last Posted Date
2022-05-19
Lead Sponsor
Editas Medicine, Inc.
Target Recruit Count
26
Registration Number
NCT03396042
Locations
🇺🇸

Casey Eye Institute - OHSU, Portland, Oregon, United States

🇫🇷

Universite Pierre et Marie Curie, Paris, France

🇺🇸

W.K. Kellogg Eye Center, Ann Arbor, Michigan, United States

and more 4 locations
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