BETSI CADWALADR UNIVERSITY HEALTH BOARD

Novel LION Trial Combines Anti-inflammatory Drug with Immunotherapy to Combat Advanced Cancers

3 months ago

• The groundbreaking LION trial investigates the combination of celecoxib with immunotherapy to treat advanced triple-negative breast cancer, non-small cell lung cancer, and renal cell carcinoma. • Led by The Christie NHS Foundation Trust, the trial aims to recruit 89 patients across six UK sites, with 11 patients already enrolled in this innovative treatment approach. • The study, funded by The Christie Charity and The Jon Moulton Charity Trust, explores whether reducing inflammation can enhance immunotherapy's effectiveness in fighting cancer.