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Clinical Trials

A Study of Extending Relugolix Dosing Intervals Through Addition of Itraconazole or Ritonavir in Prostate Cancer Patients

Phase 1

Recruiting

Conditions: Prostate Adenocarcinoma
Prostate Cancer
Prostate Cancer Metastatic

Interventions: Drug: Relugolix Pill
Drug: Itraconazole
Drug: Ritonavir

First Posted Date: 2023-01-11

Last Posted Date: 2023-10-06

Lead Sponsor: University of Chicago

Target Recruit Count: 100

Registration Number: NCT05679388

Locations: 🇺🇸
University of Chicago Comprehensive Cancer Center, Chicago, Illinois, United States

Tissue Destruction and Healing in Celiac Disease

Not Applicable

Recruiting

Conditions: Celiac Disease

Interventions: Dietary Supplement: Gluten containing snack bar

First Posted Date: 2023-01-11

Last Posted Date: 2024-10-04

Lead Sponsor: University of Chicago

Target Recruit Count: 220

Registration Number: NCT05680012

Locations: 🇺🇸
California Institute of Technology, Pasadena, California, United States
🇺🇸
The University of Chicago, Chicago, Illinois, United States
🇺🇸
Mayo Clinic, Rochester, Minnesota, United States

Tocilizumab for Acute Chest Syndrome

Phase 2

Recruiting

Conditions: Sickle Cell Disease
Acute Chest Syndrome

Interventions: Drug: Tocilizumab

First Posted Date: 2022-12-07

Last Posted Date: 2023-08-14

Lead Sponsor: University of Chicago

Target Recruit Count: 200

Registration Number: NCT05640271

Locations: 🇺🇸
University of Chicago, Chicago, Illinois, United States

Obstruction of Malignancy: Percutaneous Renal vs Endoscopic Stent

Early Phase 1

Withdrawn

Conditions: Urinary Dysfunction
Malignancy
Ureter Injury
Cancer
Urinary Obstruction
Ureter Obstruction

Interventions: Procedure: Percutaneous Nephrostomy Tube Placement
Procedure: Ureteral Stent

First Posted Date: 2022-12-07

Last Posted Date: 2024-12-19

Lead Sponsor: University of Chicago

Target Recruit Count: 2

Registration Number: NCT05640115

Locations: 🇺🇸
The University of Chicago, Chicago, Illinois, United States

PrEP Optimization Among Women to Enhance Retention and Uptake

Not Applicable

Recruiting

Conditions: PrEP Uptake

Interventions: Behavioral: PrEP Education
Behavioral: Provider training
Other: EMR Optimization
Other: PrEP Navigation
Other: Provider Audit and Feedback

First Posted Date: 2022-11-23

Last Posted Date: 2024-11-20

Lead Sponsor: University of Chicago

Target Recruit Count: 4000

Registration Number: NCT05626452

Locations: 🇺🇸
University of Chicago, Chicago, Illinois, United States

A Clinical Trial of Tolcapone in Obsessive Compulsive Disorder

Phase 2

Recruiting

Conditions: Obsessive-Compulsive Disorder
OCD

Interventions: Drug: Placebo
Drug: Tolcapone

First Posted Date: 2022-11-22

Last Posted Date: 2024-08-09

Lead Sponsor: University of Chicago

Target Recruit Count: 85

Registration Number: NCT05624528

Locations: 🇺🇸
University of Chicago Medical Center, Chicago, Illinois, United States

Preoperative PRRT Versus Surgical Cytoreduction in Metastatic Pancreatic Neuroendocrine Tumors to the Liver

Phase 1

Withdrawn

Conditions: Pancreas Cancer
Pancreatic Neuroendocrine Tumor

Interventions: Procedure: cytoreductive surgery
Drug: Lutathera - a small molecule used in Peptide Receptor Radionuclide Therapy (PRRT)
Procedure: Peptide receptor radionuclide therapy (PRRT)

First Posted Date: 2022-11-09

Last Posted Date: 2024-10-26

Lead Sponsor: University of Chicago

Target Recruit Count: 52

Registration Number: NCT05610826

Locations: 🇺🇸
The University of Chicago Comprehensive Cancer Center, Chicago, Illinois, United States

MRI Screening in Men at High Risk of Developing Prostate Cancer

Not Applicable

Recruiting

Conditions: Prostate Cancer Screening

Interventions: Other: Prostate MRI

First Posted Date: 2022-11-08

Last Posted Date: 2024-07-05

Lead Sponsor: University of Chicago

Target Recruit Count: 250

Registration Number: NCT05608694

Locations: 🇺🇸
NorthShore University Health System - Glenbrook Hospital, Glenview, Illinois, United States
🇺🇸
University of Chicago, Chicago, Illinois, United States

Testing Response Bias on Sensitive Topics in Self- Versus Enumerator-administered Surveys

Not Applicable

Recruiting

Conditions: Bias, Implicit

Interventions: Behavioral: Self-administered survey
Behavioral: Enumerator-administered survey

First Posted Date: 2022-11-02

Last Posted Date: 2022-11-02

Lead Sponsor: University of Chicago

Target Recruit Count: 7500

Registration Number: NCT05602350

Locations: 🇨🇴
Innovations for Poverty Action, Medellin, Antioquia, Colombia

The Reducing REVISITS Study: A Cluster RCT

Not Applicable

Recruiting

Conditions: COPD Exacerbation Acute
COPD

First Posted Date: 2022-10-05

Last Posted Date: 2024-05-07

Lead Sponsor: University of Chicago

Target Recruit Count: 24

Registration Number: NCT05568043

Locations: 🇺🇸
University of Chicago, Chicago, Illinois, United States

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