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Clinical Trials

Behavior Brain Responses

Early Phase 1

Completed

Conditions: Alcohol Drinking
Central Nervous System Depression
Drinking Behavior
Physiological Effects of Drugs

Interventions: Other: Placebo
Drug: Ethanol

First Posted Date: 2019-05-28

Last Posted Date: 2021-01-22

Lead Sponsor: University of Chicago

Target Recruit Count: 30

Registration Number: NCT03964350

Locations: 🇺🇸
University of Chicago, Chicago, Illinois, United States

The Effects of Therapy Dogs on Child Biology and Behavior

Not Applicable

Completed

Conditions: Stress Reaction
Behavior, Social

Interventions: Behavioral: Therapy Dog
Behavioral: Stuffed Toy Dog
Behavioral: 5 Minute Puppy Video

First Posted Date: 2019-05-14

Last Posted Date: 2024-05-09

Lead Sponsor: University of Chicago

Target Recruit Count: 188

Registration Number: NCT03949569

Locations: 🇺🇸
University of Chicago Medical Center, Chicago, Illinois, United States

De-Escalation Therapy for Human Papillomavirus Negative Disease

Phase 2

Recruiting

Conditions: Human Papilloma Virus
Squamous Cell Carcinoma
Squamous Cell Carcinoma of the Head and Neck
HPV-Related Squamous Cell Carcinoma
HNSCC

Interventions: Drug: Carboplatin
Drug: Paclitaxel
Radiation: Radiation
Drug: Nivolumab
Drug: Hydroxyurea Pill
Drug: 5-fluorouracil
Drug: Filgrastim Injection
Drug: Cisplatin

First Posted Date: 2019-05-10

Last Posted Date: 2024-08-15

Lead Sponsor: University of Chicago

Target Recruit Count: 36

Registration Number: NCT03944915

Locations: 🇺🇸
University Of Chicago Medicine Comprehensive Cancer Center, Chicago, Illinois, United States

Mood Effects of Serotonin Agonists Extended

Phase 1

Completed

Conditions: Healthy

Interventions: Drug: Placebo
Drug: Serotonin agonist - 13ug
Drug: Serotonin agonist - 26ug

First Posted Date: 2019-05-02

Last Posted Date: 2023-11-29

Lead Sponsor: University of Chicago

Target Recruit Count: 56

Registration Number: NCT03934710

Locations: 🇺🇸
Matthew Bona, Chicago, Illinois, United States

Alcohol, Behavior, and Brain Imaging

Early Phase 1

Completed

Conditions: Alcohol Drinking
Binge Drinking
Drinking Behavior
Substance-Related Disorders
Ethanol
Physiological Effects of Drugs
Central Nervous System Depressants

Interventions: Other: Placebo
Drug: Ethanol

First Posted Date: 2019-04-29

Last Posted Date: 2022-04-25

Lead Sponsor: University of Chicago

Target Recruit Count: 80

Registration Number: NCT03930446

Volume Support/Assist Control Mode Ventilation and Diaphragmatic Atrophy

Not Applicable

Recruiting

Conditions: Mechanical Ventilation Complication

Interventions: Other: Volume Support Mode Mechanical Ventilation
Other: Assist Control Mode Mechanical Ventilation

First Posted Date: 2019-04-03

Last Posted Date: 2024-07-26

Lead Sponsor: University of Chicago

Target Recruit Count: 468

Registration Number: NCT03901924

Locations: 🇺🇸
The University of Chicago Medical Center, Chicago, Illinois, United States
🇺🇸
University of Iowa, Iowa City, Iowa, United States

Assessing the Response Rate of Neo-adjuvant Taxotere and Trastuzumab in Nigerian Women With Breast Cancer

Phase 2

Recruiting

Conditions: Breast Cancer
Breast Cancer Female
HER2-positive Breast Cancer
Breast Cancer Stage II
Breast Cancer Stage III

Interventions: Drug: Docetaxel
Drug: Herceptin
Drug: FEC
Drug: LHRH agonist
Drug: Tamoxifen
Drug: Letrozole

First Posted Date: 2019-03-19

Last Posted Date: 2023-03-07

Lead Sponsor: University of Chicago

Target Recruit Count: 60

Registration Number: NCT03879577

Locations: 🇳🇬
University College Hospital, Ibadan, Nigeria, Ibadan, Nigeria

Magnetic Resonance Imaging for Detection of Peritoneal Mesothelioma

Not Applicable

Completed

Conditions: Peritoneal Mesothelioma
Mesothelioma

Interventions: Diagnostic Test: HR-MRI
Diagnostic Test: Standard CT Imaging
Diagnostic Test: Ultrasound

First Posted Date: 2019-03-08

Last Posted Date: 2024-07-31

Lead Sponsor: University of Chicago

Target Recruit Count: 26

Registration Number: NCT03867578

Locations: 🇺🇸
University Of Chicago Medicine Comprehensive Cancer Center, Chicago, Illinois, United States

A Narrative Intervention to Decrease Abortion Stigma

Not Applicable

Completed

Conditions: Stigma, Social

Interventions: Behavioral: Narrative Intervention

First Posted Date: 2019-03-06

Last Posted Date: 2020-04-20

Lead Sponsor: University of Chicago

Target Recruit Count: 215

Registration Number: NCT03865199

Locations: 🇺🇸
Planned Parenthood, Chicago, Illinois, United States

Study of Venetoclax in Combination With Decitabine in Subjects With Acute Myeloid Leukemia

Phase 1

Active, not recruiting

Conditions: Acute Myeloid Leukemia

Interventions: Drug: Decitabine
Drug: Venetoclax

First Posted Date: 2019-02-18

Last Posted Date: 2024-11-11

Lead Sponsor: University of Chicago

Target Recruit Count: 26

Registration Number: NCT03844815

Locations: 🇺🇸
University Of Chicago Medicine Comprehensive Cancer Center, Chicago, Illinois, United States

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