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Clinical Trials

Effects of Combined Alcohol and Nitrous Oxide Intake - 15

Not Applicable

Completed

Conditions: Opioid-Related Disorders
Substance-Related Disorders

Interventions: Drug: 30% Nitrous oxide
Other: 0 g/Kg ethanol
Other: 0.25 g/Kg ethanol
Other: 0.5 g/KG ethanol

First Posted Date: 1999-09-21

Last Posted Date: 2015-05-27

Lead Sponsor: University of Chicago

Target Recruit Count: 11

Registration Number: NCT00000263

Locations: 🇺🇸
University of Chicago, Anesthesia & Critical Care, Chicago, Illinois, United States

Effects of Nitrous Oxide: A Dose-Response Analysis - 5

Not Applicable

Completed

Conditions: Opioid-Related Disorders
Substance-Related Disorders

Interventions: Drug: 30% N2O
Drug: 20% N2O
Drug: 40% N2O
Drug: 10% N2O

First Posted Date: 1999-09-21

Last Posted Date: 2015-05-28

Lead Sponsor: University of Chicago

Target Recruit Count: 16

Registration Number: NCT00000253

Locations: 🇺🇸
University of Chicago, Anesthesia & Critical Care, Chicago, Illinois, United States

Effects of Alcohol History on Effects of Sevoflurane and Nitrous Oxide - 13

Phase 2

Completed

Conditions: Opioid-Related Disorders
Alcohol-Related Disorders
Substance-Related Disorders

Interventions: Drug: 30% Nitrous oxide
Other: Placebo
Drug: 0.2% sevoflurane
Drug: 0.4% sevoflurane
Drug: 0.6% sevoflurane

First Posted Date: 1999-09-21

Last Posted Date: 2015-05-27

Lead Sponsor: University of Chicago

Target Recruit Count: 14

Registration Number: NCT00000261

Locations: 🇺🇸
University of Chicago, Anesthesia & Critical Care, Chicago, Illinois, United States

Effects of Subanesthetic Concentrations of Isoflurane/Nitrous Oxide - 3

Phase 2

Completed

Conditions: Opioid-Related Disorders
Substance-Related Disorders

Interventions: Other: 100% oxygen
Drug: 30% N2O
Drug: 0.2% isoflurane
Drug: 0.4% isoflurane

First Posted Date: 1999-09-21

Last Posted Date: 2015-12-02

Lead Sponsor: University of Chicago

Target Recruit Count: 10

Registration Number: NCT00000251

Locations: 🇺🇸
University of Chicago, Anesthesia & Critical Care, Chicago, Illinois, United States

Reinforcing Effects of Brief Exposures to Nitrous Oxide - 8

Not Applicable

Completed

Conditions: Opioid-Related Disorders
Substance-Related Disorders

Interventions: Drug: 20% N2O
Drug: 40% N2O
Drug: 60% N2O
Drug: 80% N2O

First Posted Date: 1999-09-21

Last Posted Date: 2015-05-28

Lead Sponsor: University of Chicago

Target Recruit Count: 11

Registration Number: NCT00000256

Locations: 🇺🇸
University of Chicago, Anesthesia & Critical Care, Chicago, Illinois, United States

Sevoflurane vs Nitrous Oxide Inhalation at Subanesthetic Concentrations - 11

Not Applicable

Completed

Conditions: Opioid-Related Disorders
Substance-Related Disorders

Interventions: Other: Placebo
Drug: 0.3 % Sevoflurane
Drug: 0.6% Sevoflurane
Drug: 15 % Nitrous oxide
Drug: 30% Nitrous oxide

First Posted Date: 1999-09-21

Last Posted Date: 2015-05-28

Lead Sponsor: University of Chicago

Target Recruit Count: 12

Registration Number: NCT00000259

Locations: 🇺🇸
University of Chicago, Anesthesia & Critical Care, Chicago, Illinois, United States

Differential Acute Tolerance Development to Effects of Nitrous Oxide - 7

Phase 2

Completed

Conditions: Substance-Related Disorders
Opioid-Related Disorders

Interventions: Drug: Nitrous oxide

First Posted Date: 1999-09-21

Last Posted Date: 2015-05-28

Lead Sponsor: University of Chicago

Target Recruit Count: 10

Registration Number: NCT00000255

Locations: 🇺🇸
University of Chicago, Anesthesia & Critical Care, Chicago, Illinois, United States

Lack of Acute Tolerance Development to Effects of Nitrous Oxide - 4

Phase 2

Completed

Conditions: Opioid-Related Disorders
Substance-Related Disorders

Interventions: Drug: 20% N2O
Drug: 30% N2O
Drug: 0% N2O
Drug: 10% N2O
Drug: 40% N2O

First Posted Date: 1999-09-21

Last Posted Date: 2015-05-28

Lead Sponsor: University of Chicago

Target Recruit Count: 11

Registration Number: NCT00000252

Locations: 🇺🇸
University of Chicago, Anesthesia & Critical Care, Chicago, Illinois, United States

Role of Instructions in Nitrous Oxide Effects and Choice - 10

Not Applicable

Completed

Conditions: Substance-Related Disorders
Opioid-Related Disorders

Interventions: Drug: Nitrous oxide 10% & placebo
Drug: Nitrous oxide 20% & placebo
Drug: Nitrous oxide 30% & placebo
Drug: Nitrous oxide 40% and placebo

First Posted Date: 1999-09-21

Last Posted Date: 2015-05-28

Lead Sponsor: University of Chicago

Target Recruit Count: 22

Registration Number: NCT00000258

Locations: 🇺🇸
University of Chicago, Anesthesia & Critical Care, Chicago, Illinois, United States

Effects of Alcohol History on Effects of Nitrous Oxide - 9

Not Applicable

Completed

Conditions: Alcohol-Related Disorders
Opioid-Related Disorders
Substance-Related Disorders

Interventions: Drug: 0% N2O and 10% N2O
Drug: 0% N2O and 20% N2O
Drug: 0% N2O and 30% N2O
Drug: 0% N2O and 40% N2O

First Posted Date: 1999-09-21

Last Posted Date: 2015-05-28

Lead Sponsor: University of Chicago

Target Recruit Count: 19

Registration Number: NCT00000257

Locations: 🇺🇸
University of Chicago, Anesthesia & Critical Care, Chicago, Illinois, United States

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