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PFIZER INC.

PFIZER INC. logo
🇺🇸United States
Ownership
Public
Established
1849-01-01
Employees
88K
Market Cap
$163.3B
Website
http://www.pfizer.com

A Study to Understand How the Study Medicine Called ARV-471 is Processed in Healthy Adults

Phase 1
Completed
Conditions
Healthy
Interventions
First Posted Date
2023-07-05
Last Posted Date
2023-09-13
Lead Sponsor
Pfizer
Target Recruit Count
12
Registration Number
NCT05930925
Locations
🇺🇸

PPD Phase I Clinic, Austin, Texas, United States

A Study Comparing 3 Study Medicines (Encorafenib, Binimetinib, Pembrolizumab) to 2 Study Medicines (Ipilimumab and Nivolumab) in Patients With Advanced Melanoma

Phase 2
Active, not recruiting
Conditions
Melanoma
Interventions
First Posted Date
2023-07-03
Last Posted Date
2025-04-16
Lead Sponsor
Pfizer
Target Recruit Count
150
Registration Number
NCT05926960
Locations
🇩🇪

Universitaetsklinikum Tuebingen, Tübingen, Baden-württemberg, Germany

🇩🇪

Medizinische Hochschule Hannover, Hannover, Niedersachsen, Germany

🇩🇪

Universitaetsklinikum Essen, Essen, Nordrhein-westfalen, Germany

and more 21 locations

BESPONSA Injection 1 mg Special Investigation

Completed
Conditions
Acute Lymphocytic Leukemia
First Posted Date
2023-06-28
Last Posted Date
2025-02-13
Lead Sponsor
Pfizer
Target Recruit Count
421
Registration Number
NCT05923112
Locations
🇯🇵

Pfizer, Tokyo, Japan

A Study for Multiple Tablet Forms of The Study Medicine (PF-07220060) in Healthy Adults

Phase 1
Completed
Conditions
Healthy Participants
Interventions
Drug: Single dose of PF-07220060 as first Tablet Formulation
Drug: Single dose of PF-07220060 as a Tablet formulation under Rabeprazole administration
Drug: Single dose of PF-07220060 as third tablet formulation
Drug: Single dose of PF-07220060 as second Tablet Formulation
Drug: Single dose of PF-07220060 as a Tablet Formulation
First Posted Date
2023-06-28
Last Posted Date
2024-07-26
Lead Sponsor
Pfizer
Target Recruit Count
113
Registration Number
NCT05923411
Locations
🇺🇸

New Haven Clinical Research Unit, New Haven, Connecticut, United States

A Study to Learn About the Relationship Between Hepatic Impairment and Myelosuppression (Decreased Bone Marrow Function) in Breast Cancer Patients Treated With the Study Medicine Palbociclib (Pal-bow-sai-klib)

Not yet recruiting
Conditions
Breast Cancer
First Posted Date
2023-06-22
Last Posted Date
2023-06-22
Lead Sponsor
Pfizer
Target Recruit Count
1300
Registration Number
NCT05912933

A Study to Learn About the Study Medicine (PF-07293893) at Different Dose Levels in Healthy Adults

Phase 1
Completed
Conditions
Healthy Participants
Interventions
Drug: Placebo
First Posted Date
2023-06-18
Last Posted Date
2025-04-10
Lead Sponsor
Pfizer
Target Recruit Count
30
Registration Number
NCT05907395
Locations
🇧🇪

Pfizer Clinical Research Unit - Brussels, Brussels, Bruxelles-capitale, Région DE, Belgium

A Study of Vepdegestrant (ARV-471, PF-07850327) Plus Palbociclib Versus Letrozole Plus Palbociclib in Participants With Estrogen Receptor Positive, Human Epidermal Growth Factor Negative Advanced Breast Cancer

Phase 3
Active, not recruiting
Conditions
Breast Cancer
Interventions
Drug: ARV-471 (PF-07850327)
Combination Product: Palbociclib
First Posted Date
2023-06-18
Last Posted Date
2025-05-18
Lead Sponsor
Pfizer
Target Recruit Count
59
Registration Number
NCT05909397
Locations
🇸🇰

Nemocnica na okraji mesta n o, Partizanske, Slovakia

🇺🇸

BRCR Medical Center Inc, Plantation, Florida, United States

🇺🇸

Virginia Oncology Associates, Norfolk, Virginia, United States

and more 25 locations

Study of PF-07224826, as a Single Agent or in Combination With Endocrine Therapy in Participants With Breast Cancer and Other Advanced Solid Tumors.

Phase 1
Withdrawn
Conditions
Non-small Cell Lung Cancer (NSCLC)
Solid Tumors
Breast Cancer
Ovarian Cancer
Liposarcoma
Endometrial
Interventions
Combination Product: Fulvestrant
First Posted Date
2023-06-15
Last Posted Date
2023-11-08
Lead Sponsor
Pfizer
Registration Number
NCT05905341

A Study to Learn About the Study Medicine Called Nirmatrelvir/Ritonavir in People Who Are Healthy Volunteers Co-administered the Medicine Rosuvastatin

Phase 1
Completed
Conditions
Pharmacokinetics
Healthy Volunteers
Interventions
First Posted Date
2023-06-12
Last Posted Date
2024-10-28
Lead Sponsor
Pfizer
Target Recruit Count
12
Registration Number
NCT05898672
Locations
🇧🇪

Pfizer Clinical Research Unit - Brussels, Brussels, Bruxelles-capitale, Région DE, Belgium

A Study to Learn About the Safety and Immune Activity of RSVpreF in Children 2 to <18 Years of Age

Phase 1
Completed
Conditions
RESPIRATORY SYNCYTIAL VIRUS (RSV)
Interventions
Biological: RSVpreF 120 µg
Biological: RSVpreF 60 µg
First Posted Date
2023-06-12
Last Posted Date
2025-03-06
Lead Sponsor
Pfizer
Target Recruit Count
128
Registration Number
NCT05900154
Locations
🇺🇸

Senders Pediatrics, South Euclid, Ohio, United States

🇺🇸

University of Alabama at Birmingham - School of Medicine, Birmingham, Alabama, United States

🇺🇸

Stanford University Medical Center, Palo Alto, California, United States

and more 14 locations
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