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PFIZER INC.

PFIZER INC. logo
🇺🇸United States
Ownership
Public
Established
1849-01-01
Employees
88K
Market Cap
$163.3B
Website
http://www.pfizer.com

PF-07104091 as a Single Agent and in Combination Therapy

Phase 1
Active, not recruiting
Conditions
Breast Cancer
Small Cell Lung Cancer
Ovarian Cancer
Interventions
Drug: PF-07104091 monotherapy dose escalation
Drug: PF-0704091 + Fulvestrant (post CDK4/6)
Drug: PF-07104091 + palbociclib + fulvestrant
Drug: PF-07104091 + palbociclib + letrozole
Drug: PF-07104091 monotherapy dose expansion (SCLC)
Drug: PF-07104091 monotherapy dose expansion (ovarian)
Drug: PF-07104091 + Fulvestrant (post CDK4/6)
First Posted Date
2020-09-17
Last Posted Date
2024-05-16
Lead Sponsor
Pfizer
Target Recruit Count
154
Registration Number
NCT04553133
Locations
🇺🇸

Dana Farber Cancer Institute, Boston, Massachusetts, United States

🇺🇸

University of Texas MD Anderson Cancer Center, Houston, Texas, United States

🇨🇳

Tianjin Medical University Cancer Institute & Hospital, Tianjin, Tianjin, China

and more 46 locations

A Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of PF-06882961 in Japanese Adults With Type 2 Diabetes Mellitus

Phase 1
Completed
Conditions
Type 2 Diabetes Mellitus
Interventions
Drug: Placebo
Drug: PF-06882961
First Posted Date
2020-09-17
Last Posted Date
2022-03-11
Lead Sponsor
Pfizer
Target Recruit Count
37
Registration Number
NCT04552470
Locations
🇯🇵

P-one clinic, Keikokai medical corporation, Hachioji, Tokyo, Japan

Bioequivalence Study of Bosutinib Pediatric Capsule Relative to Commercial Tablet Under Fed Condition

Phase 1
Completed
Conditions
Healthy Participants
Interventions
First Posted Date
2020-09-16
Last Posted Date
2022-02-16
Lead Sponsor
Pfizer
Target Recruit Count
66
Registration Number
NCT04549480
Locations
🇳🇱

PRA Health Sciences Utrecht, Utrecht, Netherlands

🇳🇱

PRA Health Sciences, Groningen, Netherlands

Patterns of Real-World Isavuconazole Use - a Study of Patients With Mucormycosis or Invasive Aspergillosis

Completed
Conditions
Invasive Aspergillosis
Mucormycosis
First Posted Date
2020-09-16
Last Posted Date
2024-03-19
Lead Sponsor
Pfizer
Target Recruit Count
307
Registration Number
NCT04550936
Locations
🇫🇷

Hôpital Huriez CHU de Lille, Lille, France

🇫🇷

Institut de Cancérologie, Strasbourg, France

🇫🇷

CHU de Limoges, Limoges, France

and more 13 locations

20-valent Pneumococcal Conjugate Vaccine Safety and Immunogenicity Study of a 3-Dose Series in Healthy Infants

Phase 3
Completed
Conditions
Pneumococcal Disease
Interventions
Biological: 20-valent pneumococcal conjugate vaccine
Biological: 13-valent pneumococcal conjugate vaccine
First Posted Date
2020-09-14
Last Posted Date
2024-01-08
Lead Sponsor
Pfizer
Target Recruit Count
1258
Registration Number
NCT04546425
Locations
🇦🇺

Perth Children's Hospital, Nedlands, Western Australia, Australia

🇦🇺

Telethon Kids Institute, Vaccine Trials Group, Perth Children's Hospital, Nedlands, Western Australia, Australia

🇧🇪

Cliniques Universitaires Saint-Luc, Brussels, Belgium

and more 63 locations

A Study to Evaluate AAV9 Neutralizing Antibody Seroconversion in Household Contacts.

Terminated
Conditions
Household Contacts
Interventions
Other: Blood Draw
First Posted Date
2020-09-10
Last Posted Date
2024-08-06
Lead Sponsor
Pfizer
Target Recruit Count
8
Registration Number
NCT04543357
Locations
🇺🇸

Kennedy Krieger Institute, Baltimore, Maryland, United States

A FIH Study of PF-07284890 in Participants With BRAF V600 Mutant Solid Tumors With and Without Brain Involvement

Phase 1
Terminated
Conditions
Brain Neoplasms, Primary
Malignant Neoplasms
Malignant Melanoma
Brain Neoplasms
Carcinoma, Non-Small-Cell Lung
Interventions
First Posted Date
2020-09-10
Last Posted Date
2024-05-22
Lead Sponsor
Pfizer
Target Recruit Count
66
Registration Number
NCT04543188
Locations
🇺🇸

Northwestern Memorial Hospital, Chicago, Illinois, United States

🇺🇸

Massachusetts General Hospital, Boston, Massachusetts, United States

🇺🇸

Dana-Farber Cancer Institute, Boston, Massachusetts, United States

and more 73 locations

Study To Evaluate The Pharmacokinetic, Safety And Tolerability Of Single Or Multiple Subcutaneous Doses of Recifercept

Phase 1
Completed
Conditions
Healthy
Interventions
Other: Placebo
Drug: Recifercept
First Posted Date
2020-09-10
Last Posted Date
2022-01-10
Lead Sponsor
Pfizer
Target Recruit Count
24
Registration Number
NCT04543344
Locations
🇧🇪

Brussels Clinical Research Unit, Brussels, Bruxelles-capitale, Région DE, Belgium

Lorlatinib in ALK Inhibitor Treated Unresectable Advanced/Recurrent ALK-Positive Non Small Cell Lung Cancer Patients in India

Phase 4
Completed
Conditions
Advanced Non-Small Cell Lung Cancer
Interventions
First Posted Date
2020-09-09
Last Posted Date
2024-12-20
Lead Sponsor
Pfizer
Target Recruit Count
100
Registration Number
NCT04541706
Locations
🇮🇳

Rajiv Gandhi Cancer Institute And Research Centre, New Delhi, Delhi, India

🇮🇳

The Gujarat Cancer and Research Institute, Ahmedabad, Gujarat, India

🇮🇳

Apex Wellness Hospital, Nashik, Maharashtra, India

and more 9 locations

First-In-Human Study To Evaluate Safety, Tolerability, And Pharmacokinetics Following Single Ascending And Multiple Ascending Doses of PF-07304814 In Hospitalized Participants With COVID-19.

Phase 1
Completed
Conditions
Viral Disease
Interventions
Drug: PF-07304814
Drug: Placebo
First Posted Date
2020-09-01
Last Posted Date
2023-05-03
Lead Sponsor
Pfizer
Target Recruit Count
26
Registration Number
NCT04535167
Locations
🇺🇸

UC Davis Medical Center, Sacramento, California, United States

🇺🇸

Massachusetts General Hospital Translational and Clinical Research Center, Boston, Massachusetts, United States

🇧🇪

University Hospital Brugmann, Brussels, Belgium

and more 10 locations
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