Low Blood S-methyl-5-thioadenosine Linked to Postoperative Cognitive Decline
• A recent study reveals that low levels of S-methyl-5-thioadenosine (MTA) in the blood are associated with delayed neurocognitive recovery (dNCR) following surgery in elderly patients.
• The research indicates that anesthesia and surgery can lead to a decrease in MTA levels, potentially contributing to postoperative cognitive dysfunction.
• Supplementation with MTA or its precursor methionine in animal models showed promise in mitigating cognitive impairment after surgical procedures.
• These findings suggest that monitoring and potentially modulating MTA levels could be a therapeutic strategy to reduce postoperative cognitive issues.
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