University of Eastern Finland

GLP-1 agonists semaglutide and liraglutide showed decreased risk of hospitalization for AUD in a cohort study. Semaglutide had the lowest risk, followed by liraglutide. Randomized clinical trials are needed to confirm efficacy and safety in treating AUD and SUDs.

Teen smoking causes early heart damage, including enlarged heart and increased pressure, with over 50% increased risk of premature heart damage by age 24, according to a study in the Journal of the American College of Cardiology.

High-dose vitamin D supplements do not reduce type 2 diabetes risk in healthy seniors, according to a five-year study by Finnish researchers published in 'Diabetologia'.

A study published in JAMA Psychiatry suggests weight-loss drugs like Ozempic could help people with alcohol use disorder, reducing hospitalization risks by 36% for semaglutide and 28% for liraglutide. These GLP-1 agonists, which mimic a hormone regulating appetite, also showed a 32% lower risk for any substance use disorder with semaglutide and 22% with liraglutide. Clinical trials are needed to confirm these findings.

GLP-1 drugs like Ozempic and Wegovy, used for type 2 diabetes and obesity, reduce alcohol consumption and hospitalizations for alcohol use disorder (AUD), according to a study by the University of Eastern Finland and Karolinska Institutet. Patients on semaglutide showed a 36% lower risk, and those on liraglutide had a 28% lower risk. The drugs were more effective than naltrexone, the best drug for AUD. The study suggests GLP-1-agonists may aid in treating alcohol and substance use disorders, pending further validation in controlled trials.

Ozempic (semaglutide) and Victoza (liraglutide) may reduce hospitalizations by 36% and 28% respectively in those with alcohol use disorder, according to a Finnish study. The research suggests these GLP-1 drugs could outperform standard treatments, but clinical trials are needed to confirm.

The study involved ethical approval, leukapheresis for NK cell production, and adherence to GMP regulations. NK cells were manufactured using CliniMACS Prodigy, with quality control including sterility testing, cell count, and viability analysis. Cell lines and primary NK cells were isolated and cultured for cytotoxicity and degranulation assays.

Researchers identified new drug targets for retinitis pigmentosa and other inherited retinal diseases, revealing shared critical pathways in disease models, published in Molecular & Cellular Proteomics.

A study in the journal Med reports that exercising 3+ times a week during pregnancy reduces a child's asthma risk by 46%, similar to quitting smoking. This is the first observed association between maternal exercise and child asthma development, based on data from nearly 1,000 Finnish mother-child pairs.