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Regeneron Pharmaceuticals

Regeneron Pharmaceuticals logo
🇺🇸United States
Ownership
Public
Established
1988-01-01
Employees
13.4K
Market Cap
$132.4B
Website
http://www.regeneron.com
Introduction

Regeneron Pharmaceuticals, Inc. is a biotechnology company, which engages in the discovery, invention, development, manufacture, and commercialization of medicines. Its product portfolio includes the following brands: Dupixent, Evkeeza, Eylea, Inmazeb, and Kevzara. The firm accelerates the traditional drug development process through its proprietary VelociSuite technologies such as VelocImmune, which uses unique genetically humanized mice to produce optimized fully human antibodies and bispecific antibodies. The company was founded by Alferd G. Gilman, Leonard S. Schleifer, George Damis Yancopoulos, and Eric M. Shooter on January 8, 1988, and is headquartered in Tarrytown, NY.

A Study to Evaluate the Effect of Dupilumab on Exercise Capacity in Adult Patients With Asthma

Phase 4
Completed
Conditions
Asthma
Interventions
Drug: Matching placebo
First Posted Date
2019-12-18
Last Posted Date
2024-04-18
Lead Sponsor
Regeneron Pharmaceuticals
Target Recruit Count
40
Registration Number
NCT04203797
Locations
🇵🇱

Regeneron Study Site, Lubin, Dolnoslaskie, Poland

🇩🇪

IKF Pneumologie GmbH & Co. KG - Institut fuer klinische Forschung Pneumologie Frankfurt (Clinical Research Centre Respiratory Medicine) to IKF Pneumologie Frankfurt GmbH & Co KG., Frankfurt am Main, Hessen, Germany

🇩🇪

IKF Pneumologie Mainz, Helix Medical Excellence Center Mainz, Mainz, Rheinland-Pfalz, Germany

and more 21 locations

Post-authorization Safety Study in North America to Monitor Pregnancy and Infant Outcomes Following Administration of Dupilumab During Planned or Unexpected Pregnancy

Recruiting
Conditions
Asthma
Atopic Dermatitis (AD)
Interventions
First Posted Date
2019-11-22
Last Posted Date
2023-11-18
Lead Sponsor
Regeneron Pharmaceuticals
Target Recruit Count
300
Registration Number
NCT04173442
Locations
🇺🇸

Regeneron Research Site, La Jolla, California, United States

REGN3918 in Patients With Paroxysmal Nocturnal Hemoglobinuria (PNH) to Evaluate Its Long Term Safety, Efficacy and Tolerability.

Phase 3
Terminated
Conditions
Paroxysmal Nocturnal Hemoglobinuria
Interventions
First Posted Date
2019-11-14
Last Posted Date
2023-06-12
Lead Sponsor
Regeneron Pharmaceuticals
Target Recruit Count
24
Registration Number
NCT04162470
Locations
🇬🇧

Regeneron Study Site, Leeds, United Kingdom

Study of REGN4461, a Leptin Receptor Agonist Antibody, in Patients With Generalized Lipodystrophy

Phase 2
Completed
Conditions
Generalized Lipodystrophy
Interventions
Drug: Placebo
Drug: Low-Dose REGN4461
Drug: High-dose REGN4461
First Posted Date
2019-11-12
Last Posted Date
2025-02-25
Lead Sponsor
Regeneron Pharmaceuticals
Target Recruit Count
16
Registration Number
NCT04159415
Locations
🇹🇷

Regeneron Research Site, Izmir, Turkey

Study of Cemiplimab in Patients With Type of Skin Cancer Stage II to IV Cutaneous Squamous Cell Carcinoma

Phase 2
Active, not recruiting
Conditions
Cutaneous Squamous Cell Carcinoma
Interventions
First Posted Date
2019-11-07
Last Posted Date
2023-02-08
Lead Sponsor
Regeneron Pharmaceuticals
Target Recruit Count
79
Registration Number
NCT04154943
Locations
🇩🇪

Regeneron Study Site, Tübingen, Germany

Safety, Tolerability, and Efficacy of Aflibercept in Patients With Neovascular Age-Related Macular Degeneration

Phase 2
Completed
Conditions
Neovascular (Wet) Age-Related Macular Degeneration
Interventions
Drug: High-dose aflibercept
First Posted Date
2019-10-15
Last Posted Date
2023-08-14
Lead Sponsor
Regeneron Pharmaceuticals
Target Recruit Count
106
Registration Number
NCT04126317
Locations
🇵🇷

Regeneron Study Site, Arecibo, Puerto Rico

Study to Assess the Efficacy, Safety, and Tolerability of Intravitreal Aflibercept Compared to Laser Photocoagulation in Patients With Retinopathy of Prematurity

Phase 3
Completed
Conditions
Retinopathy of Prematurity
Interventions
Procedure: laser photocoagulation
First Posted Date
2019-09-24
Last Posted Date
2023-07-20
Lead Sponsor
Regeneron Pharmaceuticals
Target Recruit Count
127
Registration Number
NCT04101721
Locations
🇻🇳

Regeneron Study Site, Hue, Vietnam

First In Human (FIH) Study of REGN5459 in Adult Patients With Relapsed or Refractory Multiple Myeloma (MM)

Phase 1
Active, not recruiting
Conditions
Relapsed Multiple Myeloma
Refractory Multiple Myeloma
Interventions
First Posted Date
2019-09-10
Last Posted Date
2024-11-07
Lead Sponsor
Regeneron Pharmaceuticals
Target Recruit Count
43
Registration Number
NCT04083534
Locations
🇺🇸

Regeneron Study Site, Milwaukee, Wisconsin, United States

REGN5093 in Patients With MET-Altered Advanced Non-Small Cell Lung Cancer

Phase 1
Active, not recruiting
Conditions
NSCLC
Interventions
First Posted Date
2019-09-04
Last Posted Date
2024-03-06
Lead Sponsor
Regeneron Pharmaceuticals
Target Recruit Count
82
Registration Number
NCT04077099
Locations
🇰🇷

Regeneron Research Facility, Seoul, Korea, Republic of

🇫🇷

Regeneron Study Site, Caen cedex, France

A Trial to Find Out if REGN5678 is Safe and How Well it Works Alone or in Combination With Cemiplimab for Adult Participants With Metastatic Castration-Resistant Prostate Cancer and Other Tumors

Phase 1
Recruiting
Conditions
Metastatic Castration-resistant Prostate Cancer (mCRPC)
Clear Cell Renal Cell Carcinoma (ccRCC)
Interventions
First Posted Date
2019-06-03
Last Posted Date
2025-04-17
Lead Sponsor
Regeneron Pharmaceuticals
Target Recruit Count
345
Registration Number
NCT03972657
Locations
🇺🇸

University of Arizona, Tucson, Arizona, United States

🇺🇸

John Wayne Cancer Institute (JWCI), Santa Monica, California, United States

🇺🇸

Sarah Cannon Research Institute (SCRI), Denver, Colorado, United States

and more 14 locations
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