MedPath

Regeneron Pharmaceuticals

Regeneron Pharmaceuticals logo
🇺🇸United States
Ownership
Public
Established
1988-01-01
Employees
13.4K
Market Cap
$132.4B
Website
http://www.regeneron.com
Introduction

Regeneron Pharmaceuticals, Inc. is a biotechnology company, which engages in the discovery, invention, development, manufacture, and commercialization of medicines. Its product portfolio includes the following brands: Dupixent, Evkeeza, Eylea, Inmazeb, and Kevzara. The firm accelerates the traditional drug development process through its proprietary VelociSuite technologies such as VelocImmune, which uses unique genetically humanized mice to produce optimized fully human antibodies and bispecific antibodies. The company was founded by Alferd G. Gilman, Leonard S. Schleifer, George Damis Yancopoulos, and Eric M. Shooter on January 8, 1988, and is headquartered in Tarrytown, NY.

Single Injection of REGN475/SAR164877 in Treatment of Vertebral Fracture Pain

Phase 2
Terminated
Conditions
Back Pain
Interventions
Drug: REGN475/SAR164877
Drug: Placebo (for REGN475/SAR164877)
First Posted Date
2009-10-27
Last Posted Date
2013-05-27
Lead Sponsor
Regeneron Pharmaceuticals
Target Recruit Count
41
Registration Number
NCT01001715
Locations
🇺🇸

Sanofi-Aventis Investigational Site Number 840017, Sacramento, California, United States

🇺🇸

Sanofi-Aventis Investigational Site Number 840026, New York, New York, United States

🇺🇸

Sanofi-Aventis Investigational Site Number 840013, Boynton Beach, Florida, United States

and more 8 locations

Single Injection of REGN475/SAR164877 in the Treatment of Chronic Pancreatitis Pain

Phase 2
Terminated
Conditions
Abdominal Pain Upper
Interventions
Drug: Placebo (for REGN475/SAR164877)
Drug: REGN475/SAR164877
First Posted Date
2009-10-27
Last Posted Date
2013-05-27
Lead Sponsor
Regeneron Pharmaceuticals
Target Recruit Count
15
Registration Number
NCT01001923
Locations
🇺🇸

Sanofi-Aventis Investigational Site Number 840043, Dallas, Texas, United States

🇺🇸

Sanofi-Aventis Investigational Site Number 840003, Monterey, California, United States

🇺🇸

Sanofi-Aventis Investigational Site Number 840052, Winston Salem, North Carolina, United States

and more 14 locations

A Study to Evaluate the Safety and Efficacy of Subcutaneously Administered REGN475(SAR164877) in Patients With Sciatic Pain

Phase 2
Completed
Conditions
Sciatica
Interventions
Drug: Placebo Injection
First Posted Date
2009-10-07
Last Posted Date
2011-12-08
Lead Sponsor
Regeneron Pharmaceuticals
Target Recruit Count
159
Registration Number
NCT00991172
Locations
🇺🇸

Regeneron Investigational Site, San Antonio, Texas, United States

🇺🇸

Regeneron Invesitgational Site, West Jordan, Utah, United States

Open-label Extension Study of Intravitreal Aflibercept Injection (IAI; EYLEA®; BAY86-5321) in Neovascular ("Wet") Age-related Macular Degeneration (AMD)

Phase 3
Completed
Conditions
Neovascular Age-related Macular Degeneration
Interventions
First Posted Date
2009-08-25
Last Posted Date
2015-03-23
Lead Sponsor
Regeneron Pharmaceuticals
Target Recruit Count
323
Registration Number
NCT00964795

PREventative Study Against URate-Lowering Drug-Induced Gout Exacerbations (PRE-SURGE 2)

Phase 3
Completed
Conditions
Gout
Interventions
Drug: Placebo
First Posted Date
2009-08-13
Last Posted Date
2017-04-28
Lead Sponsor
Regeneron Pharmaceuticals
Target Recruit Count
248
Registration Number
NCT00958438

A Study of the Safety and Efficacy of REGN475(SAR164877) in Patients With Osteoarthritis of the Knee

Phase 1
Completed
Conditions
Osteoarthritis of the Knee
Interventions
Other: Placebo
First Posted Date
2009-07-23
Last Posted Date
2011-12-08
Lead Sponsor
Regeneron Pharmaceuticals
Target Recruit Count
200
Registration Number
NCT00944892

Vascular Endothelial Growth Factor (VEGF) Trap-Eye: Investigation of Efficacy and Safety in Central Retinal Vein Occlusion (CRVO)

Phase 3
Completed
Conditions
Macular Edema Secondary to Central Retinal Vein Occlusion
Interventions
Biological: VEGF Trap-Eye 2.0mg
Drug: Sham
First Posted Date
2009-07-21
Last Posted Date
2013-05-27
Lead Sponsor
Regeneron Pharmaceuticals
Target Recruit Count
189
Registration Number
NCT00943072

A Multiple-Ascending-Dose Study of the Safety and Tolerability of REGN421(SAR153192) in Patients With Advanced Solid Malignancies

Phase 1
Completed
Conditions
Advanced Solid Malignancies
Interventions
Drug: REGN421(SAR153192)
First Posted Date
2009-03-30
Last Posted Date
2014-03-26
Lead Sponsor
Regeneron Pharmaceuticals
Target Recruit Count
83
Registration Number
NCT00871559

Study Utilizing Rilonacept in Gout Exacerbations

Phase 3
Completed
Conditions
Acute Gout Flare
Interventions
Other: Placebo (for Rilonacept)
Other: Placebo (for Indomethacin)
First Posted Date
2009-03-05
Last Posted Date
2017-04-28
Lead Sponsor
Regeneron Pharmaceuticals
Target Recruit Count
225
Registration Number
NCT00855920

A Single-Dose Study of the Safety and Tolerability of REGN475(SAR164877) in Healthy Subjects

Phase 1
Completed
Conditions
Healthy
Interventions
Biological: REGN475 (SAR164877)
First Posted Date
2009-03-05
Last Posted Date
2012-05-10
Lead Sponsor
Regeneron Pharmaceuticals
Target Recruit Count
56
Registration Number
NCT00856310
© Copyright 2025. All Rights Reserved by MedPath