Makerere University

Texas Children’s Global HOPE, Baylor College of Medicine Global Health, and the Bristol Myers Squibb Foundation launch a program to combat sickle cell disease in Sub-Saharan Africa, focusing on early screening, infection prevention, and accessible treatment, starting in Tanzania and Uganda.

African populations are underrepresented in genomic research, hindering precision medicine development. Despite challenges like funding and infrastructure, progress is being made in countries like South Africa and Uganda. Initiatives like H3Africa aim to improve genomic diversity and capacity in Africa, but significant barriers remain, including brain drain and lack of government support. Efforts to build infrastructure and knowledge are ongoing, with the hope of expanding access to precision medicine across the continent.

Multi-omics risk scores (MoRS) integrate various high-throughput technologies to predict complex human diseases, showing promise in personalized medicine. Challenges include underrepresentation in genome databases, batch effects, and computational complexity. Future research should focus on integrating multi-omics data with conventional risk factors to enhance predictive performance.

Study in Catalonia identifies 8 common elements of a 'good death': comfort, placidity, safety, warmth, harmony, intimacy, respect, peacefulness, and fulfillment. Participants' unique definitions reflect individual desires for end-of-life care.

Dr. Charles Ndawula from Uganda is researching vaccines against East Coast Fever at the Department of Medical Biotechnology. His approaches include developing vaccines against the tick vector and the parasite Theileria parva. The project runs until 2027.