Surgical Resection and Intraoperative Cesium-131 Brachytherapy for Head and Neck Cancer
Early Phase 1
Completed
- Conditions
- Recurrent Head and Neck Carcinoma
- Interventions
- Radiation: BrachytherapyDrug: Cesium-131Procedure: Conventional surgery
- First Posted Date
- 2015-06-10
- Last Posted Date
- 2024-06-27
- Target Recruit Count
- 30
- Registration Number
- NCT02467738
- Locations
- 🇺🇸
Sidney Kimmel Cancer Center at Thomas Jefferson University, Philadelphia, Pennsylvania, United States
Patient Derived Cancer Cell Lines in Identifying Molecular Changes in Patients With Previously Untreated Pancreatic Cancer Receiving Gemcitabine Hydrochloride-Based Chemotherapy
Withdrawn
- Conditions
- Stage IA Pancreatic CancerStage IIB Pancreatic CancerStage III Pancreatic CancerStage IV Pancreatic CancerPancreatic Ductal AdenocarcinomaStage IB Pancreatic CancerStage IIA Pancreatic Cancer
- Interventions
- Other: Laboratory Biomarker AnalysisOther: Cytology Specimen Collection Procedure
- Locations
- 🇺🇸
Thomas Jefferson University, Philadelphia, Pennsylvania, United States
Radiation Therapy and MK-3475 for Patients With Recurrent/Metastatic Head and Neck Cancer, Renal Cell Cancer, Melanoma, and Lung Cancer
Phase 1
Completed
- Conditions
- Metastatic Renal Cell CancerRecurrent Renal Cell CarcinomaStage IV Lung CancerHead and Neck Squamous Cell CarcinomaStage III Renal Cell CancerStage IV Skin MelanomaRecurrent Head and Neck CarcinomaRecurrent Lung CarcinomaRecurrent Skin Carcinoma
- Interventions
- Radiation: Radiation Therapy (RT)Drug: MK-3475
- First Posted Date
- 2014-12-17
- Last Posted Date
- 2024-02-28
- Target Recruit Count
- 41
- Registration Number
- NCT02318771
- Locations
- 🇺🇸
Sidney Kimmel Cancer Center at Thomas Jefferson University, Philadelphia, Pennsylvania, United States
Bendamustine Hydrochloride in Treating Patients With Previously Treated Multiple Myeloma
- Locations
- 🇺🇸
Thomas Jefferson University, Philadelphia, Pennsylvania, United States
Circulating Tumor DNA in Predicting Outcomes in Patients With Stage IV Head and Neck Cancer or Stage III-IV Non-small Cell Lung Cancer
Completed
- Conditions
- Stage IVA Squamous Cell Carcinoma of the LarynxStage IVA Squamous Cell Carcinoma of the OropharynxStage IVA Verrucous Carcinoma of the Oral CavityStage IVB Verrucous Carcinoma of the Oral CavityStage IVC Squamous Cell Carcinoma of the OropharynxMetastatic Squamous Neck Cancer With Occult Primary Squamous Cell CarcinomaStage IVB Squamous Cell Carcinoma of the LarynxStage IVC Salivary Gland CancerStage IVC Squamous Cell Carcinoma of the Paranasal Sinus and Nasal CavityStage IVC Verrucous Carcinoma of the Larynx
- Interventions
- Other: Cytology specimenOther: Laboratory biomarker analysis
- First Posted Date
- 2014-09-19
- Last Posted Date
- 2024-02-16
- Target Recruit Count
- 130
- Registration Number
- NCT02245100
- Locations
- 🇺🇸
Thomas Jefferson University, Philadelphia, Pennsylvania, United States
Bendamustine Hydrochloride, Bortezomib, and Dexamethasone in Treating Patients With Newly Diagnosed Multiple Myeloma
Phase 2
Completed
- Conditions
- Stage II Multiple MyelomaStage I Multiple MyelomaStage III Multiple Myeloma
- Interventions
- First Posted Date
- 2014-08-25
- Last Posted Date
- 2019-09-13
- Target Recruit Count
- 24
- Registration Number
- NCT02224729
- Locations
- 🇺🇸
Thomas Jefferson University, Philadelphia, Pennsylvania, United States
Alisertib and Fractionated Stereotactic Radiosurgery in Treating Patients With Recurrent High Grade Gliomas
Phase 1
Completed
- Conditions
- Adult Brain Stem GliomaAdult Diffuse AstrocytomaAdult Giant Cell GlioblastomaAdult GliosarcomaAdult Mixed GliomaAdult Anaplastic AstrocytomaAdult GlioblastomaAdult Subependymal Giant Cell AstrocytomaRecurrent Adult Brain TumorAdult Anaplastic Ependymoma
- Interventions
- Radiation: Hyperfractionated radiation therapyRadiation: Stereotactic radiosurgeryDrug: AlisertibProcedure: Quality-of-life assessment
- First Posted Date
- 2014-07-10
- Last Posted Date
- 2023-09-07
- Target Recruit Count
- 17
- Registration Number
- NCT02186509
- Locations
- 🇺🇸
Sidney Kimmel Cancer Center at Thomas Jefferson University, Philadelphia, Pennsylvania, United States
Brief Mindful Meditation Practice in Improving Quality of Life in Patients With Cancer Undergoing Radiation Therapy
Not Applicable
Terminated
- Conditions
- Malignant Neoplasm
- Interventions
- Procedure: Meditation therapyOther: Quality-of-life assessmentOther: Questionnaire administration
- First Posted Date
- 2014-06-23
- Last Posted Date
- 2018-05-11
- Target Recruit Count
- 17
- Registration Number
- NCT02170350
- Locations
- 🇺🇸
Thomas Jefferson University, Philadelphia, Pennsylvania, United States
Measuring Biomarker Response to AMP-514 in Blood Samples From Patients With Solid Tumors Undergoing Radiotherapy
Completed
- Conditions
- Unspecified Adult Solid Tumor, Protocol Specific
- Interventions
- Other: Cytology specimenOther: Laboratory biomarker analysis
- First Posted Date
- 2014-06-02
- Last Posted Date
- 2017-09-06
- Target Recruit Count
- 21
- Registration Number
- NCT02153151
- Locations
- 🇺🇸
Thomas Jefferson University, Philadelphia, Pennsylvania, United States
Vemurafenib Combined With Whole Brain Radiation Therapy or Radiosurgery in Patients With BRAF Mutation-Positive Melanoma and Brain Metastases
Phase 1
Withdrawn
- Conditions
- Recurrent MelanomaStage IV MelanomaTumors Metastatic to Brain
- Interventions
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