Allergan, Inc. | MedPath

Clinical Trial to Evaluate Dexamethasone Implant with Vitrectomy for Proliferative Diabetic Retinopathy

3 months ago

• A new single-masked randomized controlled trial aims to assess the effectiveness of combining vitrectomy with intravitreal dexamethasone implant in treating proliferative diabetic retinopathy, involving 100 participants over 24 weeks. • The study will evaluate whether the combination therapy improves visual outcomes and reduces postoperative complications like macular edema compared to vitrectomy alone in PDR patients requiring surgery. • The trial, registered as ChiCTR2200059760, will measure key outcomes including corrected visual acuity, retinal reattachment rates, and central macular thickness to determine the safety and efficacy of this novel approach.

FDA Approves Novel Antibiotic Combination Emblaveo for Complex Abdominal Infections

3 months ago

• AbbVie's Emblaveo, a groundbreaking aztreonam-avibactam combination, receives FDA approval for treating complicated intra-abdominal infections with limited treatment options. • The novel therapy combines a monobactam antibiotic with a β-lactamase inhibitor, effectively targeting resistant Gram-negative bacteria including those producing metallo-β-lactamases. • Commercial availability is scheduled for Q3 2025, offering healthcare providers a crucial new tool against antimicrobial-resistant pathogens in complicated intra-abdominal infections.