SINGAPORE EYE RESEARCH INSTITUTE

Seri's focus on myopia stems from Singapore's high prevalence (80% of young adults). Initial studies in 1997 found 75% of national servicemen myopic. Seri's research, led by Prof Saw, identified predictive markers for high myopia and its complications, including retinal detachment, cataract, and glaucoma. A significant breakthrough was the use of atropine eye drops to slow myopia progression, despite side effects like glare sensitivity and blurred close-up vision.

Beam Therapeutics reports a patient death in BEAM-101 trial for sickle cell disease, unrelated to the therapy. Sana Biotechnology refocuses on autoimmune assets, reducing workforce. Ring Therapeutics expands in Singapore with new deals. Drug regulators criticized for ignoring forced labor in supply chains. OSE Therapeutics' IL-7 therapy shows positive results in ulcerative colitis trial. Japan's PMDA opens second overseas office in Washington.

Investigated local hemodynamic changes due to elevated intraocular pressure (IOP) using 3D confocal image-based computational fluid dynamics. Found arteriolar pressure, venular pressure, and capillary dropout significantly influence wall shear stress in rat retinal vasculature, potentially explaining optic disorders like glaucoma.

TME Pharma reports H1 2024 financial results, significant survival benefit of NOX-A12 + bevacizumab + radiotherapy for glioblastoma, active discussions to out-license NOX-A12, ongoing activities to externalize NOX-E36 development, and extended financial visibility into January 2025.