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National Eye Institute

National Eye Institute logo
🇺🇸United States
Ownership
Private, Subsidiary
Established
1968-01-01
Employees
101
Market Cap
-
Website
http://www.nei.nih.gov

Clinical Trials

272

Active:7
Completed:205

Trial Phases

5 Phases

Early Phase 1:3
Phase 1:61
Phase 2:27
+2 more phases

Drug Approvals

0

Drug Approvals

No drug approvals found

This company may not have drug approvals in our database

Clinical Trials

Distribution across different clinical trial phases (146 trials with phase data)• Click on a phase to view related trials

Phase 1
61 (41.8%)
Phase 3
47 (32.2%)
Phase 2
27 (18.5%)
Not Applicable
8 (5.5%)
Early Phase 1
3 (2.1%)

Training to Modify Fixational Eye Movements for Optimizing Visual Performance in People With Central Vision Loss

Not Applicable
Active, not recruiting
Conditions
Central Vision Loss From Macular Diseases
First Posted Date
2024-11-01
Last Posted Date
2024-11-01
Lead Sponsor
National Eye Institute (NEI)
Target Recruit Count
30
Registration Number
NCT06670989
Locations
🇺🇸

Herbert Wertheim School of Optometry & Vision Science, University of California Berkeley, Berkeley, California, United States

National Ophthalmic Genotyping and Phenotyping Network (eyeGENE (Registered Trademark)), Stage 3 - Expansion of DNA and Data Repositories for Rare Inherited Ophthalmic Diseases

Recruiting
Conditions
Hypopigmentation Disorder
Aniridia
Inherited Ophthalmic Diseases
Blue-cone Monochromacy
Albinism
Corneal Dystrophy
Best Disease
First Posted Date
2024-07-09
Last Posted Date
2025-05-28
Lead Sponsor
National Eye Institute (NEI)
Target Recruit Count
1000
Registration Number
NCT06491615
Locations
🇺🇸

National Eye Institute (NEI), Bethesda, Maryland, United States

🇺🇸

National Institutes of Health Clinical Center, Bethesda, Maryland, United States

Potential Environmental Causes of Uveal Coloboma

Completed
Conditions
Coloboma
First Posted Date
2021-04-06
Last Posted Date
2025-04-23
Lead Sponsor
National Eye Institute (NEI)
Target Recruit Count
76
Registration Number
NCT04833361
Locations
🇺🇸

National Eye Institute (NEI), Bethesda, Maryland, United States

Microbiome as a ThErapeutic Response Biomarker

Withdrawn
Conditions
Uveitis
First Posted Date
2021-01-25
Last Posted Date
2021-05-06
Lead Sponsor
National Eye Institute (NEI)
Registration Number
NCT04721743
Locations
🇺🇸

National Institutes of Health Clinical Center, Bethesda, Maryland, United States

Biomarkers in Ocular Inflammation and Uveitis

Completed
Conditions
Uveitis
Ocular Inflammation
First Posted Date
2020-12-31
Last Posted Date
2024-04-17
Lead Sponsor
National Eye Institute (NEI)
Target Recruit Count
69
Registration Number
NCT04690829
Locations
🇺🇸

National Eye Institute (NEI), Bethesda, Maryland, United States

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News

Repurposed Blood Pressure Drug Shows Promise for Treating Inherited Retinal Diseases with Sex-Specific Benefits

NIH researchers have discovered that reserpine, a decades-old blood pressure medication, can protect photoreceptor cells from degeneration in inherited retinal dystrophies regardless of the specific genetic mutation involved.

NIH Researchers Develop Eye Drops That Could Slow Progression of Retinitis Pigmentosa

Researchers at NIH have developed eye drops containing small peptides derived from pigment epithelium-derived factor (PEDF) that successfully slowed vision loss in animal models of retinitis pigmentosa.

ARPA-H Funds Multi-Institutional Consortium to Cure Blindness Through Eye Transplantation

The University of Colorado Anschutz Medical Campus will receive up to $46 million from ARPA-H to advance vision-restoring human whole eye transplantation.

UND Research Team to Evaluate VR Therapy for Pediatric Amblyopia in NIH-Funded Clinical Trials

• The University of North Dakota (UND) research team has been approved to conduct clinical trials for the Pediatric Eye Disease Group (PEDIG), focusing on innovative treatments for childhood eye conditions. • The trials will assess the effectiveness of virtual reality (VR) headsets as a novel approach to treating amblyopia, also known as lazy eye, in children aged 4 to 12. • These PEDIG studies, funded by the National Eye Institute (NEI) and the National Institutes of Health (NIH), aim to compare VR therapy with traditional eye patching for amblyopia treatment. • The research could potentially change the standard of care for amblyopia, offering a more engaging and effective alternative to conventional methods.

Low-Dose Antiviral Therapy Reduces Risk of Eye Disease from Shingles

Long-term, low-dose valacyclovir reduces the risk of new or worsening eye disease by 26% in patients with herpes zoster ophthalmicus (HZO).

UAMS Awarded $2.2 Million Grant to Investigate Efferocytosis in Retinopathy

The University of Arkansas for Medical Sciences (UAMS) has received a $2.2 million grant from the National Eye Institute (NEI).

AI-Powered Model Aims to Decode Genetic Variants in Stargardt Disease

Researchers are developing an AI model to classify genetic variants of the ABCA4 gene, crucial for understanding Stargardt disease.

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