CELGENE CORPORATION

🇺🇸United States
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Extension Study to Further Evaluate the Safety, Pharmacodynamics and Pharmacokinetics of Ozanimod and Active Metabolites

Completed
Conditions
Interventions
First Posted Date
2018-09-11
Last Posted Date
2019-02-06
Lead Sponsor
Celgene
Target Recruit Count
212
Registration Number
NCT03665610
Locations
🇺🇸

PPD Phase 1 Clinic, Austin, Texas, United States

🇺🇸

ICON Early Phase Services, LLC, San Antonio, Texas, United States

Efficacy and Safety Study of bb2121 Versus Standard Regimens in Subjects With Relapsed and Refractory Multiple Myeloma (RRMM)

First Posted Date
2018-08-29
Last Posted Date
2022-12-15
Lead Sponsor
Celgene
Target Recruit Count
381
Registration Number
NCT03651128
Locations
🇺🇸

Local Institution - 145, Los Angeles, California, United States

🇺🇸

Local Institution - 122, Los Angeles, California, United States

🇺🇸

Local Institution - 131, Atlanta, Georgia, United States

and more 57 locations

A Study to Evaluate the Relationship of Lenalidomide With Tumor Flare Reaction and High Tumor Burden in Participants With Relapsed or Refractory Mantle Cell Lymphoma

Recruiting
Conditions
Interventions
First Posted Date
2018-08-27
Last Posted Date
2022-10-21
Lead Sponsor
Celgene
Target Recruit Count
560
Registration Number
NCT03647124
Locations
🇬🇷

Local Institution - 511, Rio, Patras, Greece

🇬🇷

Theageneio General Hospital, Thessaloniki, Thessaloniki, Greece

🇬🇷

Metaxa Cancer Hospital, Athens, Piraeous, Greece

and more 84 locations

Drug-drug Interaction Study of Ozanimod With Pseudoephedrine to Evaluate the Effect on Blood Pressure and Heart Rate

First Posted Date
2018-08-23
Last Posted Date
2019-05-30
Lead Sponsor
Celgene
Target Recruit Count
54
Registration Number
NCT03644576
Locations
🇺🇸

ICON Early Phase Services, San Antonio, Texas, United States

Drug-drug Interaction Study of Ozanimod With Inhibitor or Inducer of CYP2C8 and/or CYP3A

First Posted Date
2018-08-10
Last Posted Date
2019-05-30
Lead Sponsor
Celgene
Target Recruit Count
100
Registration Number
NCT03624959
Locations
🇺🇸

PPD Phase 1 Clinic, Austin, Texas, United States

A Study of the First-line Treatment of Patients With Newly Diagnosed Transplant-ineligible Multiple Myeloma in Spain

Completed
Conditions
First Posted Date
2018-07-27
Last Posted Date
2019-02-04
Lead Sponsor
Celgene
Target Recruit Count
706
Registration Number
NCT03602755
Locations
🇪🇸

H. Central de Asturias, Oviedo, Asturias, Spain

🇪🇸

H. Cabueñes, Gijón, Asturias, Spain

🇪🇸

H. Althaia, Manresa, Barcelona, Spain

and more 17 locations

An Efficacy and Safety Study of bb2121 in Subjects With Relapsed and Refractory Multiple Myeloma and in Subjects With High-Risk Multiple Myeloma

First Posted Date
2018-07-26
Last Posted Date
2024-02-09
Lead Sponsor
Celgene
Target Recruit Count
264
Registration Number
NCT03601078
Locations
🇺🇸

Emory University School of Medicine, Atlanta, Georgia, United States

🇺🇸

Beth Israel Deaconess Medical Center, Boston, Massachusetts, United States

🇺🇸

Massachusetts General Hospital, Boston, Massachusetts, United States

and more 23 locations

A Study to Compare the Efficacy and Safety of JCAR017 to Standard of Care in Adult Subjects With High-risk, Transplant-eligible Relapsed or Refractory Aggressive B-cell Non-Hodgkin Lymphomas

First Posted Date
2018-07-02
Last Posted Date
2023-11-15
Lead Sponsor
Celgene
Target Recruit Count
184
Registration Number
NCT03575351
Locations
🇺🇸

Loyola University Medical Center Cardinal Bernardin Cancer Center, Maywood, Illinois, United States

🇺🇸

Local Institution - 109, Dallas, Texas, United States

🇧🇪

Local Institution - 350, Gent, Belgium

and more 51 locations

A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Single and Multiple Doses of CC-99677 in Healthy Adult Subjects

Phase 1
Completed
Conditions
Interventions
First Posted Date
2018-06-13
Last Posted Date
2020-02-26
Lead Sponsor
Celgene
Target Recruit Count
97
Registration Number
NCT03554993
Locations
🇬🇧

Quotient Clinical, Ruddington, United Kingdom

A Study to Evaluate Gluten Challenge on Immune Responses in Subjects With Celiac Disease

Completed
Conditions
First Posted Date
2018-05-11
Last Posted Date
2020-02-26
Lead Sponsor
Celgene
Target Recruit Count
5
Registration Number
NCT03521180
Locations
🇺🇸

Virginia Mason Medical Center, Seattle, Washington, United States

🇺🇸

Covance, Dallas, Texas, United States

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