University Of Birmingham

🇸🇪Sweden

Country: 🇸🇪Sweden

Ownership: Private

Established: 1900-05-01

Employees: 5K

Market Cap: -

Website: http://www.general.bham.ac.uk

Clinical Trials

Prediction of Diminutive/Small Polyp Histology: Didactic vs. Computer-based Training

Not Applicable

Conditions: Colorectal Polyp

Interventions: Other: Endoscopic characterisation training

First Posted Date: 2019-02-18

Last Posted Date: 2019-02-19

Lead Sponsor: University of Birmingham

Target Recruit Count: 160

Registration Number: NCT03843567

ROSSINI 2 - Reduction of Surgical Site Infection Using Several Novel Interventions

Phase 3

Conditions: Surgical Wound Infection
Surgery--Complications
Surgery
Surgical Site Infection

Interventions: Drug: 2% alcoholic chlorhexidine skin prep (SKIN PREP)
Device: Iodophor Antimicrobial Incise Drapes (DRAPE)
Other: NONE (Control)
Device: Gentamicin-impregnated implants/ sponges (SPONGE)

First Posted Date: 2019-02-12

Last Posted Date: 2022-11-28

Lead Sponsor: University of Birmingham

Target Recruit Count: 6610

Registration Number: NCT03838575

Locations: 🇬🇧
Queen Elizabeth Hospital Birmingham, Birmingham, United Kingdom
🇬🇧
Countess of Chester Hospital, Chester, United Kingdom

A Comparison of Reduced Dose Total Body Irradiation (TBI) and Cyclophosphamide With Fludarabine and Melphalan Reduced Intensity Conditioning in Adults With Acute Lymphoblastic Leukaemia (ALL) in Complete Remission. (ALL-RIC)

Phase 2

Active, not recruiting

Conditions: Acute Lymphoblastic Leukemia

Interventions: Drug: Fludarabine
Drug: Alemtuzumab
Drug: Melphalan
Drug: Cyclophosphamide
Drug: Mesna
Radiation: Total Body Irradiation (8Gy)

First Posted Date: 2019-01-30

Last Posted Date: 2024-05-16

Lead Sponsor: University of Birmingham

Target Recruit Count: 242

Registration Number: NCT03821610

Locations: 🇬🇧
Cardiff and Vale University Health Board, Cardiff, United Kingdom
🇬🇧
The Clatterbridge Cancer Centre Nhs Foundation Trust, Liverpool, United Kingdom
🇬🇧
University Hospitals of Leicester Nhs Trust, Leicester, United Kingdom

and more 19 locations

Study to Compare Two Functional Appliances for Class II Malocclusions

Not Applicable

Conditions: Malocclusion, Angle Class II

Interventions: Device: Twin Block appliance
Device: Button and Bead appliance

First Posted Date: 2018-12-12

Last Posted Date: 2018-12-12

Lead Sponsor: University of Birmingham

Target Recruit Count: 64

Registration Number: NCT03773783

Locations: 🇬🇧
Birmingham dental hospital, Birmingham, United Kingdom

Can Supplemental Leucine Offset Disuse-induced Muscle Atrophy?

Not Applicable

Completed

Conditions: Muscle Disuse Atrophy

Interventions: Dietary Supplement: Leucine
Dietary Supplement: Placebo

First Posted Date: 2018-12-03

Last Posted Date: 2020-06-11

Lead Sponsor: University of Birmingham

Target Recruit Count: 24

Registration Number: NCT03762278

Locations: 🇬🇧
University of Birmingham, School of Sport, Exercise and Rehabilitation Sciences, Edgbaston, West Midlands, United Kingdom

Study to Reduce Sitting in Older Adults Undergoing Hip or Knee Replacements

Not Applicable

Completed

Conditions: Arthropathy of Knee
Arthropathy of Hip
Physical Activity
Osteoarthritis
Orthopedic Disorder
Sedentary Lifestyle

Interventions: Behavioral: Sedentary behaviour reduction using motivational interviewing, education, individualised feedback, goal-setting, self-monitoring, environmental modification, and supportive phone calls

First Posted Date: 2018-11-14

Last Posted Date: 2019-07-05

Lead Sponsor: University of Birmingham

Target Recruit Count: 35

Registration Number: NCT03740412

Locations: 🇬🇧
Russells Hall Hospital, Dudley, West Midlands, United Kingdom

Exercise-meal Timing and Postprandial Glucose Control

Not Applicable

Completed

Conditions: Diabetes Mellitus, Type 2
Hyperglycemia, Postprandial
Glucose Intolerance
Physical Activity

Interventions: Behavioral: Physical activity
Dietary Supplement: Meal

First Posted Date: 2018-11-05

Last Posted Date: 2018-12-11

Lead Sponsor: University of Birmingham

Target Recruit Count: 48

Registration Number: NCT03730727

Locations: 🇬🇧
University of Birmingham, Edgbaston, West Midlands, United Kingdom

Efficacy and Safety Trial of Sodium Valproate, in Paediatric and Adult Patients With Wolfram Syndrome

Phase 2

Active, not recruiting

Conditions: Wolfram Syndrome

Interventions: Drug: Sodium Valproate 200Mg E/C Tablet
Drug: Sodium Valproate matched placebo

First Posted Date: 2018-10-24

Last Posted Date: 2024-07-31

Lead Sponsor: University of Birmingham

Target Recruit Count: 63

Registration Number: NCT03717909

Locations: 🇫🇷
Hôpital Européen Georges-Pompidou, Paris, France
🇫🇷
CHU de Montpellier, Hopital Gui de Chauliac, Montpellier, France
🇬🇧
University Hospitals Birmingham, Birmingham, United Kingdom

and more 3 locations

A Safety and Tolerability Study of ILB in Patients With Amyothrophic Lateral Sclerosis (ALS)

Phase 2

Completed

Conditions: Motor Neuron Disease
Amyotrophic Lateral Sclerosis

Interventions: Drug: ILB

First Posted Date: 2018-10-15

Last Posted Date: 2021-10-05

Lead Sponsor: University of Birmingham

Target Recruit Count: 11

Registration Number: NCT03705390

Locations: 🇬🇧
University Hospitals Birmingham NHS Foundation Trust, Birmingham, West Midlands, United Kingdom

International Trial of Selumetinib in Combination With Dexamethasone for the Treatment of Acute Lymphoblastic Leukaemia

Phase 1

Terminated

Conditions: Acute Lymphoblastic Leukemia Recurrent
Acute Lymphoblastic Leukemia, in Relapse
Acute Lymphoblastic Leukemia
Acute Lymphoblastic Leukemia, Adult
Acute Lymphoblastic Leukemia, Pediatric

Interventions: Drug: Selumetinib
Drug: Dexamethasone

First Posted Date: 2018-10-15

Last Posted Date: 2023-05-11

Lead Sponsor: University of Birmingham

Target Recruit Count: 12

Registration Number: NCT03705507

Locations: 🇬🇧
King's College Hospital, London, United Kingdom
🇳🇱
Prinses Maxima Centrum Voor Kinderoncologie, Utrecht, Netherlands
🇬🇧
Birmingham Children's Hospital, Birmingham, United Kingdom

and more 14 locations

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