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Aprea Therapeutics

🇺🇸United States
Ownership
Public
Employees
7
Market Cap
$19.1M
Website
http://www.aprea.com
Introduction

Aprea Therapeutics, Inc. is a clinical-stage biopharmaceutical company, which engages in the provision of cancer therapeutics. It is involved in the development and commercialization of novel cancer therapeutics that reactivate mutant p53 tumor suppressor protein. The company was founded by Vladimir Bykov, Klas Gota Wiman, Staffan Stromblad, Natalia Issaeva, Galina Selivanova, and Wen Jie Bao in 2002 and is headquartered in Doylestown, PA.

p53 Suppressor Activation in Recurrent High Grade Serous Ovarian Cancer, a Phase Ib/II Study of Systemic Carboplatin Combination Chemotherapy With or Without APR-246

Phase 1
Completed
Conditions
Platinum Sensitive Recurrent High-grade Serous Ovarian Cancer With Mutated p53
Interventions
First Posted Date
2014-03-28
Last Posted Date
2024-02-29
Lead Sponsor
Aprea Therapeutics
Target Recruit Count
247
Registration Number
NCT02098343
Locations
🇺🇸

University of Texas Southwestern Medical Center, Dallas, Texas, United States

🇺🇸

Dana Farber Cancer Institute, Boston, Massachusetts, United States

🇫🇷

Centre Léon Bérard, Lyon, France

and more 52 locations

Safety Study of APR-246 in Patients With Refractory Hematologic Cancer or Prostate Cancer

Phase 1
Completed
Conditions
Hematologic Neoplasms
Prostatic Neoplasms
First Posted Date
2009-05-13
Last Posted Date
2019-07-31
Lead Sponsor
Aprea Therapeutics
Target Recruit Count
36
Registration Number
NCT00900614
Locations
🇸🇪

Section of Haematology and Coagulation, Sahlgrenska University Hospital, Göteborg, Sweden

🇸🇪

Hematology Centre, M54, Karolinska Institute, Karolinska University Hospital, Huddinge, Stockholm, Sweden

🇸🇪

Clinical Research and Development Unit, Department of Oncology, Akademiska Hospital, Uppsala, Sweden

and more 3 locations
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