Royal Marsden NHS Foundation Trust

🇬🇧United Kingdom

Country: 🇬🇧United Kingdom

Ownership: Private, Subsidiary

Employees: -

Market Cap: -

Website: http://www.royalmarsden.nhs.uk

Clinical Trials

Single Modality Trans Oral Robotic Surgery for Primary Oropharyngeal Cancer: Exploring the Impact of Surgical Margins on Local Disease Recurrence

Conditions: Head and Neck Squamous Cell Carcinoma

First Posted Date: 2021-10-01

Last Posted Date: 2021-10-08

Lead Sponsor: Royal Marsden NHS Foundation Trust

Target Recruit Count: 500

Registration Number: NCT05065086

Locations: 🇬🇧
The Royal Marsden Hospital, London, United Kingdom

Safe De-escalation of Chemotherapy for Stage 1 Breast Cancer

Not Applicable

Recruiting

Conditions: Breast Cancer

Interventions: Diagnostic Test: ctDNA

First Posted Date: 2021-09-27

Last Posted Date: 2023-06-22

Lead Sponsor: Royal Marsden NHS Foundation Trust

Target Recruit Count: 400

Registration Number: NCT05058183

Locations: 🇬🇧
The Royal Marsden NHS Foundation Trust, Chelsea, London, United Kingdom
🇬🇧
The Royal Marsden NHS Foundation Trust, Sutton, Sutton, United Kingdom

Breast-implant ASsocIated anaplastIc Large Cell Lymphoma and CApsular Contracture

Recruiting

Conditions: Capsular Contracture, Implant
Breast Implant-Associated Anaplastic Large Cell Lymphoma
Breast Implant; Complications

First Posted Date: 2021-08-23

Last Posted Date: 2023-01-19

Lead Sponsor: Royal Marsden NHS Foundation Trust

Target Recruit Count: 100

Registration Number: NCT05017337

Locations: 🇬🇧
Royal Marsden Hospital NHS Foundation Trust, London, United Kingdom
🇬🇧
The Royal Marsden NHS Foundation Trust, London, United Kingdom

A Trial of Early Detection of Molecular Relapse With Circulating Tumour DNA Tracking and Treatment With Palbociclib Plus Fulvestrant Versus Standard Endocrine Therapy in Patients With ER Positive HER2 Negative Breast Cancer

Phase 2

Recruiting

Conditions: ER+ Breast Cancer
HER2-negative Breast Cancer

Interventions: Drug: Tamoxifen
Drug: Palbociclib 125Mg Tab
Drug: Letrozole
Drug: Fulvestrant injection
Drug: Exemestane
Drug: Anastrozole

First Posted Date: 2021-08-02

Last Posted Date: 2024-12-05

Lead Sponsor: Royal Marsden NHS Foundation Trust

Target Recruit Count: 1100

Registration Number: NCT04985266

Locations: 🇬🇧
Barnet Hospital, London, Barnet, United Kingdom
🇬🇧
Royal Sussex Hospital, Brighton, United Kingdom
🇬🇧
Velindre Cancer Centre, Cardiff, United Kingdom

and more 45 locations

Improving Diagnosis and Treatment of Metastatic Advanced Prostate Cancer

Conditions: Advanced Prostate Carcinoma

First Posted Date: 2021-07-30

Last Posted Date: 2021-07-30

Lead Sponsor: Royal Marsden NHS Foundation Trust

Target Recruit Count: 50

Registration Number: NCT04984395

Locations: 🇬🇧
The Royal Marsden NHS Foundation Trust, Sutton, Surrey, United Kingdom

'Lung Health Check' Biomarker Study

Conditions: Lung Cancer
Cancer

Interventions: Diagnostic Test: Blood Specimen

First Posted Date: 2021-07-12

Last Posted Date: 2022-07-18

Lead Sponsor: Royal Marsden NHS Foundation Trust

Target Recruit Count: 1000

Registration Number: NCT04957433

Locations: 🇬🇧
The Royal Brompton NHS Foundation Trust, London, United Kingdom

Changes to Function and Quality of Life and Patient Experience for Patients Undergoing Treatments for Recurrent Oropharyngeal Cancer

Active, not recruiting

Conditions: Recurrent Oropharynx Carcinoma

First Posted Date: 2021-07-07

Last Posted Date: 2024-08-09

Lead Sponsor: Royal Marsden NHS Foundation Trust

Target Recruit Count: 25

Registration Number: NCT04952922

Locations: 🇬🇧
The Royal Marsden NHS Foundation Trust, London, United Kingdom

Fulvestrant, Ipatasertib and CDK4/6 Inhibition in Metastatic ER+/HER2- Breast Cancer Patients Without ctDNA Suppression

Phase 2

Recruiting

Conditions: Metastatic Breast Cancer
ER+ Breast Cancer
Advanced Breast Cancer

Interventions: Drug: Fulvestrant 500g
Drug: Ipatasertib 300mg
Drug: CDK4/6 Inhibitor
Drug: Palbociclib 75mg-125mg

First Posted Date: 2021-06-10

Last Posted Date: 2023-10-27

Lead Sponsor: Royal Marsden NHS Foundation Trust

Target Recruit Count: 324

Registration Number: NCT04920708

Locations: 🇬🇧
Royal Cornwall Hospital, Truro, Cornwall, United Kingdom
🇬🇧
Mount Vernon Cancer Centre, London, Surrey, United Kingdom
🇬🇧
Royal Free Hospital, London, United Kingdom

and more 15 locations

Optimising Cancer Therapy And Identifying Causes of Pneumonitis USing Artificial Intelligence (COVID-19)

Completed

Conditions: Lung Cancer
Covid19
Pneumonitis

Interventions: Diagnostic Test: Machine Learning Classification of parenchymal lung change cause
Diagnostic Test: Machine Learning Classification of recurrence and non-recurrence

First Posted Date: 2021-01-22

Last Posted Date: 2022-06-29

Lead Sponsor: Royal Marsden NHS Foundation Trust

Target Recruit Count: 1211

Registration Number: NCT04721444

Locations: 🇬🇧
Imperial College Healthcare NHS Trust, London, United Kingdom
🇬🇧
Guys and St. Thomas' NHS Foundation Trust, London, United Kingdom
🇬🇧
Royal Marsden NHS Foundation Trust, London, United Kingdom

Exploratory Study of Clonal Evolution in Cancer for Patients Undergoing Transoral Robotic Surgery for Radiation Exposed Residual/reCurrent Tumours of the Upper Aerodigestive Tract

Recruiting

Conditions: Head and Neck Cancer

Interventions: Other: DNA Analysis

First Posted Date: 2020-12-17

Last Posted Date: 2024-08-09

Lead Sponsor: Royal Marsden NHS Foundation Trust

Target Recruit Count: 20

Registration Number: NCT04671940

Locations: 🇬🇧
The Royal Marsden Hospital, London, United Kingdom

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