Rambam Health Care Campus

Dr. Sivan Spitzer's SPHERE project, funded by the Russell Berrie Foundation, aims to reduce health disparities and improve diabetes and obesity rates in northern Israel through education and healthcare delivery, achieving a 40% decrease in prediabetes to diabetes transition.

Two-thirds of patients with PI3K-mutant brain metastases responded to paxalisib plus radiation therapy, with 8/12 having intracranial responses. TTFields therapy improved median progression-free survival in glioblastoma from 5.6 to 9.9 months. Proton craniospinal irradiation showed a median overall survival of 13.7 months for leptomeningeal metastases.