MedPath

ABBVIE

ABBVIE logo
🇺🇸United States
Ownership
-
Established
2013-01-01
Employees
-
Market Cap
$346B
Website
http://www.abbvie.com

Clinical Trials

1.1k

Active:102
Completed:739

Trial Phases

5 Phases

Phase 1:260
Phase 2:221
Phase 3:297
+2 more phases

Drug Approvals

1

CIMA_AEMPS:1

Drug Approvals

COMBIGAN 2 MG/ML + 5 MG/ML COLIRIO EN SOLUCION

Approval Date
Jul 14, 2025
CIMA_AEMPS

Clinical Trials

Distribution across different clinical trial phases (833 trials with phase data)• Click on a phase to view related trials

Phase 3
297 (35.7%)
Phase 1
260 (31.2%)
Phase 2
221 (26.5%)
Phase 4
37 (4.4%)
Not Applicable
18 (2.2%)

A Study to Assess the Adverse Events and How Oral Emraclidine Moves Through the Body of Healthy Elderly Adult Participants

Not Applicable
Recruiting
Conditions
Healthy Volunteer
Interventions
Drug: Placebo
First Posted Date
2025-10-21
Last Posted Date
2025-10-21
Lead Sponsor
AbbVie
Target Recruit Count
32
Registration Number
NCT07219030
Locations
🇺🇸

ACPRU, Grayslake, Illinois, United States

A Study to Assess the Mass Balance of Oral ABBV-1354 in Healthy Adult Male Participants

Not Applicable
Recruiting
Conditions
Healthy Volunteer
Interventions
First Posted Date
2025-10-21
Last Posted Date
2025-10-21
Lead Sponsor
AbbVie
Target Recruit Count
8
Registration Number
NCT07219017
Locations
🇺🇸

Fortrea Clinical Research Unit Inc, Madison, Wisconsin, United States

A Study to Assess the Safety and Effectiveness of ELAPR002f Injectable Gel in Adult Participants With Atrophic Acne Scars

Not Applicable
Not yet recruiting
Conditions
Acne Scars
First Posted Date
2025-10-06
Last Posted Date
2025-10-06
Lead Sponsor
AbbVie
Target Recruit Count
395
Registration Number
NCT07207369

A Study to Assess Adverse Events and Change in Disease Activity in Participants 12 Years of Age or Older With Locally Advanced or Metastatic Solid Tumors That Harbor MET Amplification Receiving Intravenously Infused Telisotuzumab Adizutecan

Not Applicable
Not yet recruiting
Conditions
Solid Tumors Harboring MET Amplification
Interventions
First Posted Date
2025-09-29
Last Posted Date
2025-09-29
Lead Sponsor
AbbVie
Target Recruit Count
125
Registration Number
NCT07196644

A Study to Evaluate the Safety and Effectiveness of JUVÉDERM Products in Adult Participants for the Change of Their Overall Facial Appearance

Not Applicable
Not yet recruiting
Conditions
Mid Face Volume Deficit
First Posted Date
2025-09-22
Last Posted Date
2025-09-22
Lead Sponsor
AbbVie
Target Recruit Count
94
Registration Number
NCT07186595
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News

Alector's Latozinemab Fails Phase III Trial for Frontotemporal Dementia, Company Cuts Workforce by Half

Alector's investigational antibody latozinemab failed to slow disease progression in a 96-week Phase III trial for frontotemporal dementia caused by progranulin gene mutations.

Merck KGaA's Precem-TcT ADC Shows 31% Response Rate in Colorectal Cancer, Advances to Phase III

Merck KGaA's antibody-drug conjugate precemtabart tocentecan (Precem-TcT) demonstrated a 31% objective response rate in heavily pre-treated colorectal cancer patients at 2.8mg/kg dose during Phase I trials.

RINVOQ Demonstrates Superior Efficacy Over HUMIRA in First Head-to-Head Trial for TNF-Inhibitor Experienced Rheumatoid Arthritis Patients

AbbVie's SELECT-SWITCH study marks the first Phase 3b/4 head-to-head trial comparing TNF inhibitor cycling with switching to JAK inhibitor upadacitinib in moderate to severe rheumatoid arthritis patients who failed initial TNF inhibitor therapy.

ADARx Pharmaceuticals to Present Phase 1 Data for ADX-038 siRNA Therapy at ASN Kidney Week 2025

ADARx Pharmaceuticals will present initial Phase 1 clinical data for ADX-038, an investigational siRNA therapy targeting complement factor B, at the American Society of Nephrology Kidney Week meeting in Houston.

Enveric Biosciences Engages IP Firm to Defend Patent Claims Related to AbbVie's $1.2 Billion Bretisilocin Acquisition

Enveric Biosciences has hired Fish and Richardson P.C. to defend its U.S. Patent No. 12,138,276 against a Post-Grant Review petition filed by Gilgamesh Pharmaceuticals.

FDA Approves Expanded RINVOQ Label for IBD Treatment, Allowing Earlier Use When TNF Blockers Inadvisable

The FDA approved an updated indication for RINVOQ (upadacitinib) allowing its use in IBD patients after one systemic therapy when TNF blockers are clinically inadvisable, expanding treatment options beyond the previous requirement for TNF blocker failure.

New Report Analyzes 1,775 Clinical-Stage Pharma Partnerships from 2020-2025

ResearchAndMarkets.com released a comprehensive report analyzing 1,775 clinical-stage partnering deals in pharma and biotech from 2020-2025, providing detailed financial terms and strategic insights.

AbbVie's ADC Portfolio Shows Promising Results Across Multiple Solid Tumors at ESMO 2025

AbbVie will present new data from its antibody-drug conjugate platform at ESMO 2025, featuring telisotuzumab adizutecan (Temab-A) and ABBV-706 across difficult-to-treat solid tumors.

Eli Lilly and AstraZeneca Emerge as Leading Candidates for Next Trump Administration Drug Pricing Deal

Wall Street analysts predict Eli Lilly and AstraZeneca are the most likely pharmaceutical companies to strike the next drug pricing deal with the Trump administration following Pfizer's September 29 agreement.

AbbVie's BOTOX Shows Promise for Essential Tremor in Phase 2 ELATE Trial

AbbVie's Phase 2 ELATE trial demonstrated that onabotulinumtoxinA (BOTOX) significantly improved tremor disability scores compared to placebo in patients with upper limb essential tremor.

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