Sapienza University of Rome

Aquablation Therapy Shows Comparable Efficacy to Laser Enucleation with Better Sexual Function Preservation in BPH Treatment

2 months ago

• The WATER III randomized clinical trial demonstrated that Aquablation therapy provides similar symptom relief to laser enucleation for treating benign prostatic hyperplasia (BPH) in large prostates (80-180mL). • Patients who underwent Aquablation showed significantly lower rates of ejaculatory dysfunction (14.8% vs 77.1%) and stress incontinence (0% vs 9.1%) compared to those who received laser enucleation treatment. • The three-month data revealed comparable International Prostate Symptom Score improvements between both treatments, though laser enucleation showed greater improvements in urinary flow rate and post-void residual reduction.

ESMO 2024: Novel Approaches in Personalized Medicine and AI Highlighted

6 months ago

• The PIONeeR trial explored novel immunotherapy combinations to overcome resistance to PD-1/PD-L1 inhibitors in advanced NSCLC, but did not meet its primary endpoint of improved disease control. • The Rome trial demonstrated that genomic-guided therapy significantly improved objective response rate and progression-free survival in pretreated patients with metastatic solid tumors. • Prov-GigaPath, a novel AI foundation model, shows promise in predicting genomic alterations and analyzing the tumor microenvironment from pathology slides, enhancing personalized medicine.