Landmark Study Confirms Liver Health Biomarker cT1 Predicts Cardiac and Liver Outcomes
• A major Nature Medicine study of 28,841 individuals demonstrates that Perspectum's iron corrected T1 (cT1) MRI biomarker effectively predicts both liver-related and cardiac outcomes, establishing it as a valuable non-invasive alternative to liver biopsy.
• Elevated cT1 levels (>800ms) were associated with a 30% increased risk of heart-related hospitalization, while higher levels (>875ms) led to a nine-fold increase in serious liver-related outcomes within four years.
• The research provides compelling evidence for using multiparametric MRI to identify at-risk patients with metabolic dysfunction-associated steatotic liver disease (MASLD), potentially transforming clinical practice by enabling earlier intervention.
MRI Biomarkers Show Promise in Predicting Treatment Response in MASH, Reducing Need for Biopsies
• New research validates quantitative MRI imaging as a reliable alternative to liver biopsies for assessing disease and monitoring treatment response in MASH patients.
• A reduction of 80ms in cT1, measured by Perspectum's LiverMultiScan, predicts histological response to MASH therapies, offering a non-invasive biomarker for clinical trials.
• The studies highlight the potential of non-invasive tests (NITs) to track liver health changes, potentially reducing reliance on invasive liver biopsies in MASH drug development.
• Perspectum's LiverMultiScan, an FDA-cleared technology, offers a comprehensive assessment of liver health by quantifying disease activity, severity, fat, and iron content.
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