NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES

🇺🇸United States

Country: 🇺🇸United States

Ownership: -

Employees: -

Market Cap: -

Website

Clinical Trials

The Tatelo Plus Study

Phase 1

Recruiting

Conditions: HIV
HIV Infections

Interventions: Drug: PGDM1400LS
Other: Analytic Treatment Interruption
Drug: VRC07-523LS
Drug: PGT121.414.LS
Drug: ART Regimen prior to enrolling in Step 1a
Drug: ART Regimen prior to enrolling in Step 1b

First Posted Date: 2024-07-18

Last Posted Date: 2024-11-20

Lead Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)

Target Recruit Count: 41

Registration Number: NCT06508749

Locations: 🇧🇼
Francistown CRS (CRS #31891), Francistown, Botswana
🇧🇼
Botswana Harvard Health Partnership CRS (CRS #31833), Gaborone, Botswana

Targeted Investigation of Microbiome 2 Treat Atopic Dermatitis (TIME-2)

Phase 2

Not yet recruiting

Conditions: Atopic Dermatitis

Interventions: Drug: ShA9 Topical Gel
Drug: Clobetasol Ointment
Drug: Hydrocortisone Ointment
Drug: Fluocinonide Ointment
Drug: Placebo (Vehicle) Topical Gel

First Posted Date: 2024-07-16

Last Posted Date: 2024-12-10

Lead Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)

Target Recruit Count: 86

Registration Number: NCT06504160

Locations: 🇺🇸
University of California, San Diego: Dermatology Clinical Trials Unit, San Diego, California, United States
🇺🇸
Icahn School of Medicine at Mount Sinai: Department of Pediatrics Allergy & Immunology, New York, New York, United States
🇺🇸
National Jewish Health: Division of Pediatric Allergy and Clinical Immunology, Denver, Colorado, United States

and more 6 locations

Modeling Host-Pathogen Interaction Using Lymphoid Organoids

Recruiting

Conditions: Staphylococcal Infections

First Posted Date: 2024-06-28

Last Posted Date: 2025-01-09

Lead Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)

Target Recruit Count: 500

Registration Number: NCT06479837

Locations: 🇺🇸
National Institute of Allergy and Infectious Diseases (NIAID), Bethesda, Maryland, United States
🇺🇸
National Institutes of Health Clinical Center, Bethesda, Maryland, United States

Dupilumab as Add-On Therapy for Hypereosinophilic Syndrome With Partial Clinical Response to Eosinophil-Depleting Biologic Agents

Phase 2

Recruiting

Conditions: Hypereosinophilic Syndrome

Interventions: Biological: dupilumab

First Posted Date: 2024-06-27

Last Posted Date: 2025-01-09

Lead Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)

Target Recruit Count: 30

Registration Number: NCT06477653

Locations: 🇺🇸
National Institutes of Health Clinical Center, Bethesda, Maryland, United States

Belatacept in Heart Transplantation

Phase 2

Recruiting

Conditions: Heart Transplant

Interventions: Drug: Belatacept
Drug: Tacrolimus
Drug: Mycophenolate Mofetil/Sodium
Drug: Prednisone

First Posted Date: 2024-06-27

Last Posted Date: 2024-12-31

Lead Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)

Target Recruit Count: 66

Registration Number: NCT06478017

Locations: 🇺🇸
Cedars Sinai Heart Institute/ Cedars Sinai Medical (Site # 71146), Los Angeles, California, United States
🇺🇸
Tampa General Hospital (Site # 71150), Tampa, Florida, United States
🇺🇸
NYU Langone Health (Site # 71177), New York, New York, United States

and more 1 locations

Belumosudil to Block Chronic Lung Allograft Dysfunction (CLAD) in High Risk Lung Transplant Recipients

Phase 2

Not yet recruiting

Conditions: Lung Transplant

Interventions: Drug: Placebo for Belumosudil
Drug: Belumosudil

First Posted Date: 2024-06-26

Last Posted Date: 2024-06-26

Lead Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)

Target Recruit Count: 234

Registration Number: NCT06476132

Locations: 🇺🇸
NYU Langone Health (Site #: 71177), New York, New York, United States
🇺🇸
University of California, Los Angeles (Site #: 71123), Los Angeles, California, United States
🇺🇸
Johns Hopkins (Site #: 71119), Baltimore, Maryland, United States

and more 6 locations

Pregnancy Registry in Mali

Recruiting

Conditions: Pregnancy Related
Malaria

First Posted Date: 2024-06-21

Last Posted Date: 2024-08-29

Lead Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)

Target Recruit Count: 9500

Registration Number: NCT06468319

Locations: 🇲🇱
Kalifabougou MRTC Clinic, Kalifabougou, Région De Koulikoro, Mali

L9LS MAb in Malian Infants

Phase 1

Recruiting

Conditions: Malaria

Interventions: Biological: L9LS
Other: Normal Saline

First Posted Date: 2024-06-14

Last Posted Date: 2024-08-28

Lead Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)

Target Recruit Count: 180

Registration Number: NCT06461026

Locations: 🇲🇱
Torodo MRTC Clinic, Torodo, Région De Koulikoro, Mali
🇲🇱
Faladje MRTC Clinic, Faladje, Région De Koulikoro, Mali
🇲🇱
Kalifabougou MRTC Clinic, Kalifabougou, Région De Koulikoro, Mali

Phase 1, Randomized, Double-Blind, Placebo-controlled Study to Evaluate the Safety and Tolerability of an Enterovirus D68-specific Monoclonal Antibody in Healthy Adults

Phase 1

Active, not recruiting

Conditions: Enterovirus Infection

Interventions: Other: Placebo for EV68-228-N
Biological: EV68-228-N

First Posted Date: 2024-06-05

Last Posted Date: 2025-01-03

Lead Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)

Target Recruit Count: 36

Registration Number: NCT06444048

Locations: 🇺🇸
University of Maryland, School of Medicine, Center for Vaccine Development and Global Health, Baltimore, Maryland, United States
🇺🇸
Vanderbilt University Medical Center, Nashville, Tennessee, United States

Safety and Immunogenicity Trial of MPV/S-2P SARS-CoV-2 Vaccine in Adults

Phase 1

Active, not recruiting

Conditions: COVID-19

Interventions: Biological: MPV/S-2P

First Posted Date: 2024-06-04

Last Posted Date: 2024-12-13

Lead Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)

Target Recruit Count: 60

Registration Number: NCT06441968

Locations: 🇺🇸
The Hope Clinic of Emory University, Decatur, Georgia, United States
🇺🇸
NYU Grossman Long Island School of Medicine - Vaccine Center, Mineola, New York, United States
🇺🇸
Baylor College of Medicine, Houston, Texas, United States

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