MedPath

Bio-Path Holdings

Bio-Path Holdings logo
🇺🇸United States
Ownership
Public
Established
2007-01-01
Employees
10
Market Cap
-
Website
http://www.biopathholdings.com
Introduction

Bio-Path Holdings, Inc. is a biotechnology company, which engages in the development of therapies for acute myeloid leukemia (AML) and chronic myeloid leukemia (CML). Its product pipeline includes Prexigebersen, BP1001-A, BP1002, and BP1003. The company was founded by Peter H. Nielsen, Douglas P. Morris, Gabriel Lopez-Berestein and Ana Tari Ashizawa on May 10, 2007 and is headquartered in Bellaire, TX.

Clinical Trials

6

Active:1
Completed:1

Trial Phases

2 Phases

Phase 1:5
Phase 2:1

Drug Approvals

0

Drug Approvals

No drug approvals found

This company may not have drug approvals in our database

Clinical Trials

Distribution across different clinical trial phases (6 trials with phase data)• Click on a phase to view related trials

Phase 1
5 (83.3%)
Phase 2
1 (16.7%)

A Clinical Trial of BP1002 in Patients With Refractory/Relapsed Acute Myeloid Leukemia (AML)

Phase 1
Recruiting
Conditions
Acute Myeloid Leukemia, in Relapse
Acute Myeloid Leukemia Refractory
Interventions
Drug: BP1002; Liposomal Bcl-2 Antisense Oligodeoxynucleotide
First Posted Date
2022-01-13
Last Posted Date
2025-03-10
Lead Sponsor
Bio-Path Holdings, Inc.
Target Recruit Count
48
Registration Number
NCT05190471
Locations
🇺🇸

Scripps Green Hospital, La Jolla, California, United States

🇺🇸

UCLA Medical Center, Los Angeles, California, United States

🇺🇸

Weill Cornell Medical College - NewYork-Presbyterian Hospital, New York, New York, United States

and more 1 locations

BP1001-A in Patients With Advanced or Recurrent Solid Tumors

Phase 1
Recruiting
Conditions
Solid Tumor, Adult
Carcinoma, Ovarian Epithelial
Fallopian Tube Neoplasms
Endometrial Cancer
Peritoneal Cancer
Solid Tumor
Interventions
Drug: BP1001-A (Liposomal Grb2 Antisense Oligonucleotide)
Drug: BP1001-A (Liposomal Grb2 Antisense Oligonucleotide) with paclitaxel
First Posted Date
2019-12-12
Last Posted Date
2025-03-25
Lead Sponsor
Bio-Path Holdings, Inc.
Target Recruit Count
50
Registration Number
NCT04196257
Locations
🇺🇸

Holy Cross Hospital, Silver Spring, Maryland, United States

🇺🇸

Karmanos Cancer Institute, Detroit, Michigan, United States

🇺🇸

Mary Crowley Cancer Research, Dallas, Texas, United States

and more 1 locations

A Clinical Trial of BP1002 in Patients With Advanced Lymphoid Malignancies

Phase 1
Active, not recruiting
Conditions
Waldenstrom Macroglobulinemia
Chronic Lymphocytic Leukemia (CLL)
Follicular Lymphoma
Mantle Cell Lymphoma
Cutaneous T-cell Lymphoma (CTCL)
Small Lymphocytic Lymphoma (SLL)
Marginal Zone Lymphoma
Peripheral T-cell Lymphoma (PTCL)
Hodgkin Lymphoma
DLBCL
Interventions
Drug: L-Bcl-2 antisense oligonucleotide
First Posted Date
2019-08-28
Last Posted Date
2025-02-24
Lead Sponsor
Bio-Path Holdings, Inc.
Target Recruit Count
30
Registration Number
NCT04072458
Locations
🇺🇸

Georgia Cancer Center, Augusta, Georgia, United States

🇺🇸

New York Medical College / Westchester Medical Center, Valhalla, New York, United States

🇺🇸

Sarah Cannon Research Institute/Tennesee Oncology, Nashville, Tennessee, United States

and more 2 locations

Clinical Trial of BP1001 (Liposomal Grb2 Antisense Oligonucleotide) in Combination With Dasatinib in Patients With Ph + CML Who Have Failed TKI, Ph+ AML, Ph+ MDS

Phase 1
Withdrawn
Conditions
Acute Myeloid Leukemia
Myelodysplastic Syndrome
Chronic Myelogenous Leukemia, Ph1-Positive
Interventions
Drug: BP1001 (varying dose)
Drug: BP1001 (fixed dose)
First Posted Date
2016-10-05
Last Posted Date
2020-05-28
Lead Sponsor
Bio-Path Holdings, Inc.
Registration Number
NCT02923986
Locations
🇺🇸

The University of Texas M.D. Anderson Cancer Center, Houston, Texas, United States

Clinical Trial of BP1001 in Combination With With Venetoclax Plus Decitabine in AML

Phase 2
Recruiting
Conditions
Acute Myeloid Leukemia (AML)
Interventions
Drug: BP1001 in combination with Ventoclax plus decitabine
First Posted Date
2016-05-25
Last Posted Date
2025-03-07
Lead Sponsor
Bio-Path Holdings, Inc.
Target Recruit Count
108
Registration Number
NCT02781883
Locations
🇺🇸

UCLA Medical Center, Los Angeles, California, United States

🇺🇸

Georgia Cancer Center at Augusta University, Augusta, Georgia, United States

🇺🇸

University of Kansas Cancer Center, Fairway, Kansas, United States

and more 6 locations
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News

Bio-Path Holdings Reports Clinical Progress Across Cancer Pipeline with Promising Patient Responses

Bio-Path Holdings reported clinical progress across its cancer drug pipeline, with two AML patients demonstrating continued treatment durability after receiving over 15 treatment cycles and remaining in complete remission.

Bio-Path Holdings Advances Cancer Therapies with Clinical Trial Progress and $4 Million Funding

Bio-Path Holdings has secured $4 million in private placement to bolster its financial position for advancing clinical trials of its cancer treatments.

Oncolytics Biotech and Bio-Path Holdings Announce Promising Cancer Therapy Advancements

Oncolytics Biotech presented data at the ASCO GI Symposium, highlighting pelareorep's potential in treating relapsed anal and metastatic pancreatic cancers.

Bio-Path Holdings Expands DNAbilize Platform into Obesity and Advances Oncology Programs

Bio-Path Holdings initiated a therapeutic program, BP1001-A, for obesity and related metabolic diseases, marking the first non-cancer application of its DNAbilize® technology.

Bio-Path Holdings' BP1003 Demonstrates Therapeutic Potential in Diverse Cancers

Bio-Path Holdings announces a publication in _Biomedicines_ highlighting BP1003's therapeutic potential across various cancer types.

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