AstraZeneca

AstraZeneca logo
🇬🇧United Kingdom
Ownership
Public
Employees
89.9K
Market Cap
$270.3B
Website
http://www.astrazeneca.co.uk
Introduction

AstraZeneca Plc is a holding company, which engages in the research, development, manufacture, and commercialization of prescription medicines. The company was founded on June 17, 1992 and is headquartered in Cambridge, the United Kingdom.

biospace.com
·

AstraZeneca, Daiichi Sankyo's Dato-DXd Fails to Significantly Improve Overall Survival in ...

AstraZeneca and Daiichi Sankyo's Phase III TROPION-Lung01 study showed datopotamab deruxtecan (Dato-DXd) failed to significantly improve overall survival in non-small cell lung cancer patients, with a 6% drop in death risk and 16% OS benefit in non-squamous NSCLC, both missing statistical significance. Despite this, AstraZeneca remains confident in Dato-DXd's potential role in lung cancer treatment.

AstraZeneca eyes up transition to eco-friendly inhaler propellant

AstraZeneca completed clinical studies for Breztri, its COPD inhaler, transitioning to a next-gen propellant with near-zero global warming potential. First regulatory submissions in Europe, UK, and China expected by end of 2024. Breztri, using eco-friendly HFO-1234ze, aims to reduce carbon footprint and generated $677m in global sales in 2023, with projections to reach $2.14bn by 2030.
statnews.com
·

Breakthrough therapies have given Duchenne muscular dystrophy families like mine hope

Recent FDA approvals of three new therapies for Duchenne muscular dystrophy have increased hope but also confusion among families. The lack of long-term data on gene therapy, especially in older and nonambulatory patients, and the potential for future treatment ineligibility due to antibody creation, adds to the complexity of decision-making. Families need better guidance from neurologists on therapy priorities and polypharmacy, as well as support to make informed decisions without judgment.
cnbc.com
·

AstraZeneca shares fall 5% on disappointing lung cancer drug trial results

AstraZeneca shares dropped 5% after disappointing lung cancer drug trial results, with its experimental drug datopotamab deruxtecan not significantly improving overall survival for patients.

AstraZeneca falls as cancer drug disappoints, analysts cuts FDA approval chances

Oliver Haill, a seasoned financial journalist, joined Proactive, a global financial news provider with hubs in major finance centers. Proactive specializes in medium and small-cap markets, covering sectors like biotech, mining, and emerging technologies. The company uses technology to enhance workflows but maintains human authorship for all content.
expresspharma.in
·

AstraZeneca says lung cancer drug trial shows no significant improvement in overall survival

AstraZeneca's TROPION-Lung01 trial for lung cancer drug Dato-DXd showed no significant improvement in overall survival, raising concerns for its future.
globenewswire.com
·

Monoclonal Antibodies Market to Reach USD 804.7 Billion By

The Global Monoclonal Antibodies Market is projected to grow from USD 279.8 billion in 2024 to USD 804.7 billion by 2033, at a CAGR of 12.5%. North America is expected to dominate with a 47.5% share in 2024, driven by strong healthcare infrastructure and high R&D investments. Oncology is projected to lead the application segment with a 46.2% share. Major companies include Roche, Novartis, Johnson & Johnson, Pfizer, and Merck.
bnnbloomberg.ca
·

Daiichi Sankyo Plunges on Mixed Trial Result of Lung Cancer Drug

AstraZeneca and Daiichi Sankyo shares fell due to mixed results in a late-stage trial for their lung cancer drug Dato-DXd, which showed some patients lived longer but overall results were not statistically significant. The drug is expected to be approved based on overall survival and progression-free survival improvements.
pharmacytimes.com
·

TROP2 Predictive of Clinical Outcomes in Patients With NCSLC Treated With Datopotamab

TROP2 protein in NSCLC predicts better outcomes with datopotamab deruxtecan (dato-DXd) vs. docetaxel, per TROPION-Lung01 trial analysis. Dato-DXd reduced progression risk by 43% in TROP2-QCS biomarker-positive patients vs. 25% overall, with no new safety concerns. AstraZeneca and Roche Tissue Diagnostics plan to co-develop a TROP2-QCS biomarker companion diagnostic.
© Copyright 2024. All Rights Reserved by MedPath