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AstraZeneca

AstraZeneca logo
🇬🇧United Kingdom
Ownership
Public
Employees
89.9K
Market Cap
$270.3B
Website
http://www.astrazeneca.co.uk
Introduction

AstraZeneca Plc is a holding company, which engages in the research, development, manufacture, and commercialization of prescription medicines. The company was founded on June 17, 1992 and is headquartered in Cambridge, the United Kingdom.

A Phase I Study to Investigate the Effect of Renal Impairment on the Pharmacokinetics, Safety, and Tolerability of AZD0780

Phase 1
Completed
Conditions
Renal Impairment
Interventions
First Posted Date
2024-09-19
Last Posted Date
2025-02-20
Lead Sponsor
AstraZeneca
Target Recruit Count
30
Registration Number
NCT06592482
Locations
🇺🇸

Research Site, Saint Paul, Minnesota, United States

Establish FeNO Cut-off Value for Predicting Budesonide-formoterol Response in Chronic Cough Suggestive of CVA Patients.

Not Applicable
Recruiting
Conditions
Cough-Variant Asthma
Interventions
First Posted Date
2024-09-19
Last Posted Date
2025-04-25
Lead Sponsor
AstraZeneca
Target Recruit Count
1000
Registration Number
NCT06590740
Locations
🇨🇳

Research Site, Zunyi, China

A Study in Participants With Obesity or Overweight With at Least One Weight-related Comorbidity

Phase 2
Active, not recruiting
Conditions
Obesity or Overweight
Interventions
Drug: Placebo comparator
First Posted Date
2024-09-19
Last Posted Date
2025-05-16
Lead Sponsor
AstraZeneca
Target Recruit Count
262
Registration Number
NCT06595238
Locations
🇬🇧

Research Site, Rotherham, United Kingdom

A Phase I/IIa Study to Investigate the Safety, Tolerability, Pharmacokinetics, and Efficacy of AZD0022 as Monotherapy and in Combination With Anti-cancer Agents in Adult Participants With Tumours Harbouring a KRASG12D Mutation

Phase 1
Recruiting
Conditions
Advanced Solid Tumours
Non-Small Cell Lung Cancer (NSCLC)
Pancreatic Ductal Adenocarcinoma (PDAC)
Colorectal Cancer (CRC)
Interventions
First Posted Date
2024-09-19
Last Posted Date
2025-05-18
Lead Sponsor
AstraZeneca
Target Recruit Count
430
Registration Number
NCT06599502
Locations
🇬🇧

Research Site, Newcastle-Upon-Tyne, United Kingdom

Effects of AZD5004 in Adults Who Are Living With Obesity or Overweight With at Least 1 Weight-related Comorbidity

Phase 2
Active, not recruiting
Conditions
Obesity or Overweight
Interventions
Drug: Placebo
First Posted Date
2024-08-30
Last Posted Date
2025-05-02
Lead Sponsor
AstraZeneca
Target Recruit Count
310
Registration Number
NCT06579092
Locations
🇬🇧

Research Site, Witney, United Kingdom

Efficacy, Safety, and Tolerability of Once Daily Oral Administration of AZD5004 Versus Placebo for 26 Weeks in Adults With Type 2 Diabetes Mellitus.

Phase 2
Recruiting
Conditions
Diabetes Mellitus, Type 2
Interventions
Drug: Placebo (placebo matching AZD5004 film-coated tablet)
First Posted Date
2024-08-30
Last Posted Date
2025-04-27
Lead Sponsor
AstraZeneca
Target Recruit Count
384
Registration Number
NCT06579105
Locations
🇬🇧

Research Site, Yate, United Kingdom

Study to Investigate the Effect of Hepatic Impairment on the Pharmacokinetics, Safety, and Tolerability of AZD0780

Phase 1
Completed
Conditions
Hepatic Impairment
Interventions
First Posted Date
2024-08-29
Last Posted Date
2025-02-10
Lead Sponsor
AstraZeneca
Target Recruit Count
16
Registration Number
NCT06576765
Locations
🇺🇸

Research Site, San Antonio, Texas, United States

A Multifaceted Intervention to Improve Bleeding Management Among Patients Using Oral Anticoagulants (IMPACT-BLEEDING)

Not yet recruiting
Conditions
Bleeding
First Posted Date
2024-08-28
Last Posted Date
2024-08-28
Lead Sponsor
AstraZeneca
Target Recruit Count
168
Registration Number
NCT06575517

Real-world Study Assessing Efficacy of TezepeLumaB in Patients With Severe Asthma Regardless of Phenotype in Russia

Recruiting
Conditions
Severe Asthma
First Posted Date
2024-08-22
Last Posted Date
2025-05-08
Lead Sponsor
AstraZeneca
Target Recruit Count
110
Registration Number
NCT06566885
Locations
🇷🇺

Research Site, Tomsk, Russian Federation

A Study of AZD0486 Monotherapy or in Combination With Other Anti-Cancer Agents for Mature B-Cell Malignancies

Phase 1
Recruiting
Conditions
Large B-cell Lymphoma
B-cell Non-Hodgkin Lymphoma
Mantle-cell Lymphoma
Chronic Lymphocytic Leukaemia
Small Lymphocytic Leukaemia
Interventions
First Posted Date
2024-08-21
Last Posted Date
2025-02-14
Lead Sponsor
AstraZeneca
Target Recruit Count
180
Registration Number
NCT06564038
Locations
🇬🇧

Research Site, Oxford, United Kingdom

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