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AstraZeneca

AstraZeneca logo
🇬🇧United Kingdom
Ownership
Public
Employees
89.9K
Market Cap
$270.3B
Website
http://www.astrazeneca.co.uk
Introduction

AstraZeneca Plc is a holding company, which engages in the research, development, manufacture, and commercialization of prescription medicines. The company was founded on June 17, 1992 and is headquartered in Cambridge, the United Kingdom.

A Double-blind, Placebo-controlled, Crossover Study to Assess the Effect of Aclidinium Bromide 400 μg Bid on COPD Symptoms and Sleep Quality After 3 Weeks of Treatment in Patients With Stable Moderate-to-severe Chronic Obstructive Pulmonary Disease (COPD)

Phase 4
Completed
Conditions
Chronic Obstructive Pulmonary Disease (COPD)
Interventions
First Posted Date
2014-06-03
Last Posted Date
2016-11-09
Lead Sponsor
AstraZeneca
Target Recruit Count
30
Registration Number
NCT02153489
Locations
🇩🇪

Pulmonary Research Institute at the Lung Clinic Grosshansdorf, Grosshansdorf, Germany

🇩🇪

Pneumologische Lehrklinik der Universitätsmedizin Göttingen, Immenhausen, Germany

Multicentric, Transversal, Descriptive, Epidemiological Study on the Management of Asthma in Asthmatic Middle East Adult Population

Completed
Conditions
Asthma
First Posted Date
2014-06-03
Last Posted Date
2016-11-08
Lead Sponsor
AstraZeneca
Target Recruit Count
7294
Registration Number
NCT02153411
Locations
🇦🇪

Research Site, Sharjah, Nis-rme-xxx-2014/1, United Arab Emirates

A Phase I/III Study of D961H 10 mg and 20 mg in Japanese Paediatric Patients With Gastrointestinal Acid Related Diseases

Phase 3
Completed
Conditions
Reflux Esophagitis (RE)
Zollinger-Ellison Syndrome
Duodenal Ulcer (DU)
Non-erosive Reflux Esophagitis Disease (NERD)
Gastric Ulcer (GU)
Anastomotic Ulcer (AU)
Interventions
Drug: D961H sachet 10 mg
Drug: D961H capsule 20 mg
Drug: D961H capsule 10mg
First Posted Date
2014-06-03
Last Posted Date
2017-01-19
Lead Sponsor
AstraZeneca
Target Recruit Count
55
Registration Number
NCT02153398
Locations
🇯🇵

Research Site, Yokohama-shi, Japan

AZD9291 (Osimertinib) Versus Platinum-Based Doublet-Chemotherapy in Locally Advanced or Metastatic Non-Small Cell Lung Cancer

Phase 3
Completed
Conditions
Anticancer Treatment
Interventions
Drug: Chemotherapy
Drug: Cross-over to Osimertinib
First Posted Date
2014-06-02
Last Posted Date
2025-01-07
Lead Sponsor
AstraZeneca
Target Recruit Count
421
Registration Number
NCT02151981
Locations
🇬🇧

Research Site, Wolverhampton, United Kingdom

A Clinical Study to Evaluate Symbicort Turbuhaler Used 'as Needed' in Adults and Adolescents With Asthma.

Phase 3
Completed
Conditions
Asthma
Interventions
First Posted Date
2014-05-29
Last Posted Date
2019-11-15
Lead Sponsor
AstraZeneca
Target Recruit Count
3850
Registration Number
NCT02149199
Locations
🇻🇳

Research Site, Hochiminh, Vietnam

AZD9291 in Combination With Ascending Doses of Novel Therapeutics

Phase 1
Active, not recruiting
Conditions
Advanced Non Small Cell Lung Cancer
Interventions
Drug: Part A - AZD9291 in combination with AZD6094
Drug: Part A - AZD9291 in combination with continuous selumetinib (Asian subjects)
Drug: Part A - AZD9291 in combination with MEDI4736
Drug: Part C - AZD6094 monotherapy (Japan only)
Drug: Part B - AZD9291 in combination with AZD6094
Drug: Part A - AZD9291 in combination with continuous selumetinib (non-Asian subjects)
Drug: Part B - AZD9291 in combination with MEDI4736
Drug: Part C - AZD9291 in combination with AZD6094 (Japan only)
Drug: Part A - AZD9291 in combination with intermittent selumetinib
Drug: Part D - AZD9291 in combination with AZD6094
Drug: Part B - AZD9291 in combination with selumetinib
First Posted Date
2014-05-21
Last Posted Date
2025-04-10
Lead Sponsor
AstraZeneca
Target Recruit Count
344
Registration Number
NCT02143466
Locations
🇺🇦

Research Site, Vinnytsia, Ukraine

Phase I Open Label Dose Escalation Study to Investigate the Safety & Pharmacokinetics of AZD5312 in Patients With Androgen Receptor Tumors

Phase 1
Completed
Conditions
Advanced Solid Tumours With Androgen Receptor Pathway as a Potential Factor
Interventions
First Posted Date
2014-05-21
Last Posted Date
2016-07-14
Lead Sponsor
AstraZeneca
Target Recruit Count
32
Registration Number
NCT02144051
Locations
🇬🇧

Research Site, London, United Kingdom

The Severity of Newly Diagnosed Asthma Patients and the Result of Initial 12 Weeks Treatment in China

Completed
Conditions
Asthma
First Posted Date
2014-05-21
Last Posted Date
2017-09-15
Lead Sponsor
AstraZeneca
Target Recruit Count
4817
Registration Number
NCT02143739
Locations
🇨🇳

Research Site, Zhengzhou, China

Ph1 to Assess Safety, Tolerability of Tremelimumab/ Tremelimumab+MEDI4736 in Japanese Solid Malignancies/ Mesothelioma

Phase 1
Completed
Conditions
Part A and B: Advanced Solid Malignancies
Part C: Malignant Mesothelioma
Interventions
First Posted Date
2014-05-19
Last Posted Date
2018-12-12
Lead Sponsor
AstraZeneca
Target Recruit Count
65
Registration Number
NCT02141347
Locations
🇯🇵

Research Site, Yokohama-shi, Japan

Benralizumab Efficacy in Moderate to Very Severe Chronic Obstructive Pulmonary Disease (COPD) With Exacerbation History

Phase 3
Completed
Conditions
Moderate to Very Severe Chronic Obstructive Pulmonary Disease
Interventions
First Posted Date
2014-05-15
Last Posted Date
2019-06-13
Lead Sponsor
AstraZeneca
Target Recruit Count
1656
Registration Number
NCT02138916
Locations
🇬🇧

Research Site, Wolverhampton, United Kingdom

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