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AstraZeneca

AstraZeneca logo
🇬🇧United Kingdom
Ownership
Public
Employees
89.9K
Market Cap
$270.3B
Website
http://www.astrazeneca.co.uk
Introduction

AstraZeneca Plc is a holding company, which engages in the research, development, manufacture, and commercialization of prescription medicines. The company was founded on June 17, 1992 and is headquartered in Cambridge, the United Kingdom.

A Placebo Controlled Study Comparing AZD1775+ Docetaxel Versus Placebo+Docetaxel to Treat Lung Cancer

Phase 2
Terminated
Conditions
Previously Treated Non Small Cell Lung Cancer
Interventions
Drug: Antimitotic Agent
Drug: pegfiligrastim
First Posted Date
2014-03-14
Last Posted Date
2016-06-14
Lead Sponsor
AstraZeneca
Target Recruit Count
48
Registration Number
NCT02087176
Locations
🇺🇸

Research Site, Milwaukee, Wisconsin, United States

Phase II Dose Finding Study of RDEA3170 Versus Placebo in Japanese Patients With Gout or Asymptomatic Hyperuricemia

Phase 2
Completed
Conditions
Gout and Hyperuricemia
Interventions
First Posted Date
2014-03-05
Last Posted Date
2019-09-24
Lead Sponsor
AstraZeneca
Target Recruit Count
204
Registration Number
NCT02078219
Locations
🇯🇵

Research Site, Shinagawa-ku, Japan

Efficacy and Safety Study of Benralizumab to Reduce OCS Use in Patients With Uncontrolled Asthma on High Dose Inhaled Corticosteroid Plus LABA and Chronic OCS Therapy

Phase 3
Completed
Conditions
Asthma
Interventions
Biological: Benralizumab
Biological: Placebo
First Posted Date
2014-03-03
Last Posted Date
2018-06-08
Lead Sponsor
AstraZeneca
Target Recruit Count
220
Registration Number
NCT02075255
Locations
🇺🇦

Research Site, Vinnytsia, Ukraine

A First Time in Man Study to Assess the Safety, Tolerability and Pharmacokinetics of AZD1979 in Healthy Males

Phase 1
Terminated
Conditions
Healthy Subjects
Interventions
Drug: Placebo to match
First Posted Date
2014-02-27
Last Posted Date
2014-07-29
Lead Sponsor
AstraZeneca
Target Recruit Count
116
Registration Number
NCT02072993
Locations
🇺🇸

Research Site, Overland Park, Kansas, United States

Post Marketing Surveillance of Roflumilast in Korea

Completed
Conditions
Chronic Obstructive Pulmonary Disease
Interventions
First Posted Date
2014-02-21
Last Posted Date
2017-06-22
Lead Sponsor
AstraZeneca
Target Recruit Count
1837
Registration Number
NCT02068456

Ticagrelor China Pharmacokinetic/Pharmacodynamic Study

Phase 4
Completed
Conditions
Stable Coronary Heart Disease (CHD)
Interventions
Drug: Inhibition of Platelet Aggregation by "Brilinta"(Ticagrelor)
First Posted Date
2014-02-17
Last Posted Date
2016-05-11
Lead Sponsor
AstraZeneca
Target Recruit Count
61
Registration Number
NCT02064985
Locations
🇨🇳

Research Site, Beijing, China

To Assess the Pharmacokinetics, Safety and Tolerability of Selumetinib in Patients With Hepatic Impairment and Healthy Subjects

Phase 1
Completed
Conditions
Solid Tumors
Interventions
First Posted Date
2014-02-14
Last Posted Date
2016-07-21
Lead Sponsor
AstraZeneca
Target Recruit Count
32
Registration Number
NCT02063230
Locations
🇺🇸

Research Site, Orlando, Florida, United States

To Assess the Pharmacokinetics, Safety and Tolerability of Selumetinib in Renal Impaired Subjects and Healthy Subjects

Phase 1
Completed
Conditions
Solid Tumours
Interventions
First Posted Date
2014-02-14
Last Posted Date
2015-06-30
Lead Sponsor
AstraZeneca
Target Recruit Count
24
Registration Number
NCT02063204
Locations
🇺🇸

Research Site, Orlando, Florida, United States

Bioequivalence/Food Effect - Saxa/Dapa Dual Fixed Dose Combination (FDC)

Phase 1
Completed
Conditions
Type 2 Diabetes Mellitus
Interventions
Drug: Saxagliptin/Dapagliflozin FDC
First Posted Date
2014-02-11
Last Posted Date
2015-06-10
Lead Sponsor
AstraZeneca
Target Recruit Count
72
Registration Number
NCT02060201

Two-part Pharmacokinetic and Pharmacodynamic Study of LAS190792 in Patients With Asthma and COPD

Phase 1
Completed
Conditions
Chronic Obstructive Pulmonary Disease (COPD)
Asthma
Interventions
Drug: LAS190792 Dose 1
Drug: LAS190792 Dose 2
Drug: Placebo
Drug: LAS190792 Dose 2 (Part 2)
Drug: LAS190792 Dose 5
Drug: LAS190792 Dose 3
Drug: LAS190792 Dose 4
Drug: LAS190792 Dose 6
Drug: LAS190792 Dose 1 (Part 2)
First Posted Date
2014-02-11
Last Posted Date
2019-06-21
Lead Sponsor
AstraZeneca
Target Recruit Count
55
Registration Number
NCT02059434
Locations
🇬🇧

Medicines Evaluation Unit Ltd (MEU), Manchester, United Kingdom

🇬🇧

Quintiles Drug Research Unit at Guy's Hospital, London, United Kingdom

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