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AstraZeneca

AstraZeneca logo
🇬🇧United Kingdom
Ownership
Public
Employees
89.9K
Market Cap
$270.3B
Website
http://www.astrazeneca.co.uk
Introduction

AstraZeneca Plc is a holding company, which engages in the research, development, manufacture, and commercialization of prescription medicines. The company was founded on June 17, 1992 and is headquartered in Cambridge, the United Kingdom.

Evaluation of Effectiveness of Two Dosing Regimens of Fostamatinib Compared to Placebo in Patients With Rheumatoid Arthritis (RA) Who Are Taking Methotrexate and Have Had Inadequate Response to Single TNF-alpha Antagonist

Phase 3
Completed
Conditions
Rheumatoid Arthritis
Interventions
Drug: placebo
First Posted Date
2010-09-09
Last Posted Date
2014-04-07
Lead Sponsor
AstraZeneca
Target Recruit Count
323
Registration Number
NCT01197755
Locations
🇬🇧

Research Site, Wirral, United Kingdom

Evaluation of Effectiveness of Two Dosing Regimens of Fostamatinib Compared to Placebo in Patients With Rheumatoid Arthritis (RA) Who Are Taking Methotrexate But Not Responding.

Phase 3
Completed
Conditions
Rheumatoid Arthritis
Interventions
First Posted Date
2010-09-09
Last Posted Date
2014-04-07
Lead Sponsor
AstraZeneca
Target Recruit Count
923
Registration Number
NCT01197521
Locations
🇬🇧

Research Site, Wirral, United Kingdom

Investigation of Efficacy, Safety and Tolerability of Once and Twice Daily Doses of AZD1981 in Asthmatic Patients

Phase 2
Completed
Conditions
Asthma Patients
Interventions
Drug: Placebo
First Posted Date
2010-09-09
Last Posted Date
2013-11-06
Lead Sponsor
AstraZeneca
Target Recruit Count
1144
Registration Number
NCT01197794
Locations
🇺🇦

Research Site, Zaporozhye, Ukraine

Evaluation of Effectiveness of Two Dosing Regimens of Fostamatinib Compared to Placebo in Patients With Rheumatoid Arthritis (RA) Who Are Taking Disease Modifying Anti-rheumatic Drug (DMARD) But Not Responding.

Phase 3
Completed
Conditions
Rheumatoid Arthritis
Interventions
First Posted Date
2010-09-09
Last Posted Date
2014-04-17
Lead Sponsor
AstraZeneca
Target Recruit Count
913
Registration Number
NCT01197534
Locations
🇬🇧

Research Site, Swindon, United Kingdom

A Study to Assess the Efficacy and Safety of TC-5214 as an Adjunct Therapy in Patients With Major Depressive Disorder.

Phase 3
Completed
Conditions
Major Depressive Disorder
Interventions
Drug: Placebo
First Posted Date
2010-09-09
Last Posted Date
2014-04-11
Lead Sponsor
AstraZeneca
Target Recruit Count
696
Registration Number
NCT01197508
Locations
🇺🇦

Research Site, Vinnytsya, Ukraine

Single Ascending Dose Study to Assess the Safety, Tolerability and Pharmacokinetics of AZD4451

Phase 1
Completed
Conditions
Bipolar Disorder
Interventions
Drug: Placebo
First Posted Date
2010-09-08
Last Posted Date
2011-08-01
Lead Sponsor
AstraZeneca
Target Recruit Count
63
Registration Number
NCT01196676
Locations
🇺🇸

Research Site, Overland Park, Kansas, United States

Pharmacokinetics in Adolescents

Phase 1
Completed
Conditions
Asthma
Interventions
Drug: AZD1981 100 mg twice daily for 61/2 days
First Posted Date
2010-09-08
Last Posted Date
2011-03-07
Lead Sponsor
AstraZeneca
Target Recruit Count
21
Registration Number
NCT01196689
Locations
🇸🇪

Research Site, Uppsala, Sweden

A Study of BMS-512148 (Dapagliflozin) in Patients With Type 2 Diabetes With Inadequately Controlled Hypertension on an ACEI or ARB and an Additional Antihypertensive Medication

Phase 3
Completed
Conditions
Type 2 Diabetes
Interventions
First Posted Date
2010-09-06
Last Posted Date
2016-12-29
Lead Sponsor
AstraZeneca
Target Recruit Count
2245
Registration Number
NCT01195662
Locations
🇺🇸

Abington Memorial Hos/Feasterville Family Health Care Center, Feasterville, Pennsylvania, United States

🇺🇸

The Clinical Trial Center, Llc, Jenkintown, Pennsylvania, United States

🇺🇸

Research Across America, Reading, Pennsylvania, United States

and more 152 locations

Evaluation of Histamine H3 Receptor Radioligand [11C]AZ12807110 and Histamine H3 Receptor Occupancy of AZD5213 After Oral Administration

Phase 1
Completed
Conditions
Brain Distribution of [11C]AZ12807110 and AZD5213
Interventions
Other: [11C]AZ12807110
First Posted Date
2010-09-03
Last Posted Date
2015-01-28
Lead Sponsor
AstraZeneca
Target Recruit Count
13
Registration Number
NCT01194986
Locations
🇸🇪

Research Site, Uppsala, Sweden

Preliminary Anti-tumour Activity of mTor Kinase Inhibitor in Advanced Tumours

Phase 1
Withdrawn
Conditions
Cancer
Advanced Solid Tumours
Lymphomas
Interventions
First Posted Date
2010-09-02
Last Posted Date
2011-05-16
Lead Sponsor
AstraZeneca
Target Recruit Count
63
Registration Number
NCT01194193
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