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AstraZeneca

AstraZeneca logo
🇬🇧United Kingdom
Ownership
Public
Employees
89.9K
Market Cap
$270.3B
Website
http://www.astrazeneca.co.uk
Introduction

AstraZeneca Plc is a holding company, which engages in the research, development, manufacture, and commercialization of prescription medicines. The company was founded on June 17, 1992 and is headquartered in Cambridge, the United Kingdom.

Phase III, Open-label, Study of First-line Dato-DXd in Combination With Rilvegostomig for Advanced Non-squamous NSCLC With High PD-L1 Expression (TC ≥ 50%) and Without Actionable Genomic Alterations

Phase 3
Recruiting
Conditions
Non-Small Cell Lung Cancer
Interventions
First Posted Date
2024-04-10
Last Posted Date
2025-04-29
Lead Sponsor
AstraZeneca
Target Recruit Count
675
Registration Number
NCT06357533
Locations
🇬🇧

Research Site, Truro, United Kingdom

OverTTuRe: Characteristics, Treatment Patterns and Outcomes of Patients With ATTR Amyloidosis

Recruiting
Conditions
ATTR Amyloidosis
Interventions
Other: no intervention
First Posted Date
2024-04-10
Last Posted Date
2025-05-08
Lead Sponsor
AstraZeneca
Target Recruit Count
55000
Registration Number
NCT06355934
Locations
🇬🇧

Research Site, London, United Kingdom

A Study to Investigate the Pharmacokinetics of Baxdrostat When Given Alone and in Combination With Itraconazole in Healthy Participants

Phase 1
Completed
Conditions
Healthy Participants
Interventions
First Posted Date
2024-04-10
Last Posted Date
2024-07-03
Lead Sponsor
AstraZeneca
Target Recruit Count
14
Registration Number
NCT06357520
Locations
🇺🇸

Research Site, Brooklyn, Maryland, United States

Phase III, Open-label Study of First-line Osimertinib With or Without Datopotamab Deruxtecan for EGFRm Locally Advanced or Metastatic Non-small Cell Lung Cancer

Phase 3
Recruiting
Conditions
Non-small Cell Lung Cancer
Interventions
First Posted Date
2024-04-05
Last Posted Date
2025-04-09
Lead Sponsor
AstraZeneca
Target Recruit Count
582
Registration Number
NCT06350097
Locations
🇻🇳

Research Site, Vinh, Vietnam

A Positron-emission Tomography Study to Determine Brain Exposure of [11C]Savolitinib in Healthy Volunteers

Phase 1
Completed
Conditions
Healthy Volunteers
Interventions
First Posted Date
2024-04-04
Last Posted Date
2024-07-11
Lead Sponsor
AstraZeneca
Target Recruit Count
7
Registration Number
NCT06348355
Locations
🇸🇪

Research Site, Solna, Sweden

AZD0901 Compared With Investigator's Choice of Therapy in Participants With Second- or Later-line Advanced or Metastatic Gastric or Gastroesophageal Junction Adenocarcinoma Expressing Claudin18.2

Phase 3
Recruiting
Conditions
Gastric Cancer
Gastroesophageal Junction Cancer
Interventions
First Posted Date
2024-04-04
Last Posted Date
2025-05-09
Lead Sponsor
AstraZeneca
Target Recruit Count
589
Registration Number
NCT06346392
Locations
🇻🇳

Research Site, Vinh, Vietnam

A Study to Investigate the Efficacy and Safety of Baxdrostat in Participants With Uncontrolled Hypertension on Two or More Medications Including Participants With Resistant Hypertension

Phase 3
Recruiting
Conditions
Uncontrolled Hypertension
Resistant Hypertension
Interventions
Drug: Placebo
First Posted Date
2024-04-03
Last Posted Date
2025-01-10
Lead Sponsor
AstraZeneca
Target Recruit Count
300
Registration Number
NCT06344104
Locations
🇻🇳

Research Site, Hochiminh, Vietnam

A Study to Assess the Lung Exposure Bioequivalence of Budesonide, Glycopyrronium, & Formoterol (BGF) Metered Dose Inhaler (MDI) Hydrofluoroolefin (HFO) With a Spacer (Treatment B), BGF MDI Hydrofluoroalkane (HFA) With a Spacer (Treatment A), as Well as BGF MDI HFO Without a Spacer (Treatment C)

Phase 1
Not yet recruiting
Conditions
Healthy
Interventions
Device: AeroChamber Plus Flow-Vu Spacer
First Posted Date
2024-04-01
Last Posted Date
2024-07-05
Lead Sponsor
AstraZeneca
Target Recruit Count
132
Registration Number
NCT06340581
Locations
🇩🇪

Research Site, Berlin, Germany

Transthyretin Amyloidosis Cardiomyopathy in Patients With HFpEF in Russia

Terminated
Conditions
Transthyretin Amyloidosis Cardiomyopathy, Heart Failure With Preserved Ejection Fraction
First Posted Date
2024-04-01
Last Posted Date
2025-03-19
Lead Sponsor
AstraZeneca
Target Recruit Count
1770
Registration Number
NCT06338839
Locations
🇷🇺

Research Site, Yaroslavl, Russian Federation

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