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AstraZeneca

AstraZeneca logo
🇬🇧United Kingdom
Ownership
Public
Employees
89.9K
Market Cap
$270.3B
Website
http://www.astrazeneca.co.uk
Introduction

AstraZeneca Plc is a holding company, which engages in the research, development, manufacture, and commercialization of prescription medicines. The company was founded on June 17, 1992 and is headquartered in Cambridge, the United Kingdom.

BURAN: Benralizumab on Airway Dynamics in Severe Eosinophilic Asthma Using Functional Respiratory Imaging

Phase 4
Completed
Conditions
Asthma
Interventions
Combination Product: Benralizumab
First Posted Date
2022-09-23
Last Posted Date
2025-03-25
Lead Sponsor
AstraZeneca
Target Recruit Count
45
Registration Number
NCT05552508
Locations
🇬🇧

Research Site, Nottingham, United Kingdom

Study to Assess the Efficacy and Safety of Adjuvant Osimertinib in NSCLC With Uncommon EGFRm

Phase 2
Active, not recruiting
Conditions
Non-small Cell Lung Cancer
Interventions
First Posted Date
2022-09-21
Last Posted Date
2025-04-08
Lead Sponsor
AstraZeneca
Target Recruit Count
51
Registration Number
NCT05546866
Locations
🇨🇳

Research Site, Tianjin, China

Andexanet Alfa and 4F-PCC Use in Patients Hospitalised With an Anticoagulant-related Major Bleed

Completed
Conditions
Anticoagulant-related Major Bleed
Interventions
First Posted Date
2022-09-21
Last Posted Date
2023-11-28
Lead Sponsor
AstraZeneca
Target Recruit Count
5480
Registration Number
NCT05548777
Locations
🇺🇸

Research Site, Agoura Hills, California, United States

Study to Evaluate the Effect of CIN-107 on the Pharmacokinetics of the MATE Substrate, Metformin, in Healthy Subjects

Phase 1
Completed
Conditions
Hypertension
Interventions
First Posted Date
2022-09-02
Last Posted Date
2023-08-14
Lead Sponsor
AstraZeneca
Target Recruit Count
27
Registration Number
NCT05526690
Locations
🇺🇸

Medpace Clinical Pharmacology Unit, Cincinnati, Ohio, United States

A Study of 5 Years of Adjuvant Osimertinib in Completely Resected Epidermal Growth Factor Receptor Mutation (EGFRm) Non-small Cell Lung Carcinoma (NSCLC)

Phase 2
Active, not recruiting
Conditions
Stage II-IIIB Non-small Cell Lung Carcinoma
Interventions
First Posted Date
2022-09-02
Last Posted Date
2025-05-28
Lead Sponsor
AstraZeneca
Target Recruit Count
188
Registration Number
NCT05526755
Locations
🇬🇧

Research Site, Nottingham, United Kingdom

Pharmacokinetics of Cotadutide in Participants With Hepatic Impairment

Phase 1
Terminated
Conditions
Hepatic Impairment
Interventions
Combination Product: Cotadutide
First Posted Date
2022-08-26
Last Posted Date
2023-03-21
Lead Sponsor
AstraZeneca
Target Recruit Count
24
Registration Number
NCT05517226
Locations
🇺🇸

Research Site, San Antonio, Texas, United States

Zibotentan and Dapagliflozin Combination, EvAluated in Liver Cirrhosis (ZEAL Study)

Phase 2
Recruiting
Conditions
Liver Cirrhosis
First Posted Date
2022-08-25
Last Posted Date
2025-03-25
Lead Sponsor
AstraZeneca
Target Recruit Count
195
Registration Number
NCT05516498
Locations
🇬🇧

Research Site, Nottingham, United Kingdom

A Study to Evaluate the Safety and Pharmacokinetics of Ceralasertib in Combination With Durvalumab in Chinese Patients With Advanced Solid Tumours

Phase 1
Active, not recruiting
Conditions
Advanced Solid Tumours
Interventions
First Posted Date
2022-08-24
Last Posted Date
2025-02-13
Lead Sponsor
AstraZeneca
Target Recruit Count
14
Registration Number
NCT05514132
Locations
🇨🇳

Research Site, Shandong, China

A Bioavailability and Food Effect Study of AZD5462 in Healthy Volunteers

Phase 1
Completed
Conditions
Healthy Participants
Interventions
First Posted Date
2022-08-23
Last Posted Date
2023-11-09
Lead Sponsor
AstraZeneca
Target Recruit Count
16
Registration Number
NCT05512806
Locations
🇺🇸

Research Site, Brooklyn, Maryland, United States

Assess the Safety, Tolerability, and Pharmacokinetics of AZD6234 Following Single Ascending Dose Administration to Healthy Subjects Who Are Overweight or Obese

Phase 1
Completed
Conditions
Healthy Participants
Interventions
Drug: Placebo
Combination Product: Acetaminophen
First Posted Date
2022-08-22
Last Posted Date
2023-12-26
Lead Sponsor
AstraZeneca
Target Recruit Count
54
Registration Number
NCT05511025
Locations
🇺🇸

Research Site, Brooklyn, Maryland, United States

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