MedPath

AstraZeneca

AstraZeneca logo
🇬🇧United Kingdom
Ownership
Public
Employees
89.9K
Market Cap
$270.3B
Website
http://www.astrazeneca.co.uk
Introduction

AstraZeneca Plc is a holding company, which engages in the research, development, manufacture, and commercialization of prescription medicines. The company was founded on June 17, 1992 and is headquartered in Cambridge, the United Kingdom.

A Study to Investigate the Absolute Bioavailability, Absorption, Metabolism, Distribution and Excretion of [14C]AZD5363 (Capivasertib)

Phase 1
Completed
Conditions
Healthy Volunteer
Interventions
Drug: [14C]AZD5363 (Capivasertib)
First Posted Date
2022-06-15
Last Posted Date
2022-07-22
Lead Sponsor
AstraZeneca
Target Recruit Count
7
Registration Number
NCT05419401
Locations
🇬🇧

Research Site, Ruddington, United Kingdom

Study of AZD9574 as Monotherapy and in Combination With Anti-cancer Agents in Participants With Advanced Solid Malignancies

Phase 1
Recruiting
Conditions
Advanced Solid Malignancies
Interventions
Drug: [11C]AZ1419 3391
Drug: Datopotamab Deruxtecan (Dato-DXd)
First Posted Date
2022-06-14
Last Posted Date
2025-05-28
Lead Sponsor
AstraZeneca
Target Recruit Count
535
Registration Number
NCT05417594
Locations
🇬🇧

Research Site, Newcastle Upon Tyne, United Kingdom

Tracking Treatment Pathways in Adult Patients With Hyperkalemia.

Completed
Conditions
Hyperkalemia
First Posted Date
2022-06-07
Last Posted Date
2025-01-06
Lead Sponsor
AstraZeneca
Target Recruit Count
1331
Registration Number
NCT05408039
Locations
🇬🇧

Research Site, Stevenage, United Kingdom

A First-in-human Study to Evaluate the Safety and Tolerability of AZD8853 in Participants With Selected Advanced/Metastatic Solid Tumours

Phase 1
Terminated
Conditions
Urinary Bladder Neoplasms
Colorectal Cancer
Carcinoma, Non-Small-Cell Lung
Interventions
First Posted Date
2022-05-31
Last Posted Date
2024-10-01
Lead Sponsor
AstraZeneca
Target Recruit Count
17
Registration Number
NCT05397171
Locations
🇨🇦

Research Site, Toronto, Ontario, Canada

Tezepelumab Efficacy and Safety in Reducing Oral Corticosteroid Use in Adults With Oral Corticosteroid Dependent Asthma

Phase 3
Terminated
Conditions
Asthma
Interventions
First Posted Date
2022-05-31
Last Posted Date
2025-04-09
Lead Sponsor
AstraZeneca
Target Recruit Count
125
Registration Number
NCT05398263
Locations
🇹🇷

Research Site, Izmir, Turkey

A Study to Assess the Effect of AZD5462 on the Pharmacokinetics of Midazolam, Rosuvastatin and Digoxin

Phase 1
Completed
Conditions
Healthy Participants
Interventions
First Posted Date
2022-05-27
Last Posted Date
2023-12-13
Lead Sponsor
AstraZeneca
Target Recruit Count
32
Registration Number
NCT05395117
Locations
🇺🇸

Research Site, Brooklyn, Maryland, United States

PASS of Paediatric Patients Initiating Selumetinib

Recruiting
Conditions
Neurofibromatosis Type 1
First Posted Date
2022-05-24
Last Posted Date
2025-05-06
Lead Sponsor
AstraZeneca
Target Recruit Count
125
Registration Number
NCT05388370
Locations
🇬🇧

Research Site, Newcastle, United Kingdom

A Study to Assess the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of AZD0780 in Healthy Subjects

Phase 1
Completed
Conditions
Dyslipidemia
Interventions
First Posted Date
2022-05-20
Last Posted Date
2024-07-19
Lead Sponsor
AstraZeneca
Target Recruit Count
183
Registration Number
NCT05384262
Locations
🇬🇧

Research Site, Harrow, United Kingdom

FAsenra Safety Trial in India

Phase 4
Completed
Conditions
In Adult Patients of Severe Asthma With Eosinophilic Phenotype in India
Interventions
First Posted Date
2022-05-20
Last Posted Date
2024-12-11
Lead Sponsor
AstraZeneca
Target Recruit Count
139
Registration Number
NCT05384938
Locations
🇮🇳

Research Site, Vishakhapatnam, India

A Randomized, Open-label, Dose-ranging Study in Adults and Pediatric Individuals ≥ 12 Years of Age to Assess the Safety, Immunogenicity, Pharmacokinetics, and Pharmacodynamics of AZD7442, for Pre-exposure Prophylaxis of COVID-19

Phase 2
Terminated
Conditions
Coronavirus Disease 2019 (COVID-19)
Interventions
First Posted Date
2022-05-17
Last Posted Date
2024-10-23
Lead Sponsor
AstraZeneca
Target Recruit Count
251
Registration Number
NCT05375760
Locations
🇺🇸

Research Site, Annandale, Virginia, United States

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