AstraZeneca

AstraZeneca logo
🇬🇧United Kingdom
Ownership
Public
Employees
89.9K
Market Cap
$270.3B
Website
http://www.astrazeneca.co.uk
Introduction

AstraZeneca Plc is a holding company, which engages in the research, development, manufacture, and commercialization of prescription medicines. The company was founded on June 17, 1992 and is headquartered in Cambridge, the United Kingdom.

Imfinzi Plus Imjudo Shows Significant Five-Year Survival Improvement in Unresectable Liver Cancer

Imfinzi plus Imjudo combo significantly improved five-year overall survival rates in unresectable hepatocellular carcinoma patients compared to sorafenib, with 19.6% surviving vs. 9.4%.
prnewswire.com
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Sanofi shipping BEYFORTUS® in US to help protect babies against RSV disease

Sanofi ships BEYFORTUS doses to US healthcare providers and CDC for RSV prevention, ensuring access for eligible babies. A new FDA-approved filling line expands manufacturing capacity, with another line expected to boost supply for the 2024/2025 RSV season. BEYFORTUS is the first long-acting monoclonal antibody for RSV LRTD prevention in newborns and infants up to 24 months.
thirdeyenews.in
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Renal Cell Carcinoma Clinical Trial Pipeline Market | Application, Size, Share Analysis 2024-2031

The Renal Cell Carcinoma Clinical Trial Pipeline Market is projected to grow significantly from 2024 to 2031, driven by technological innovations, rising demand, and regulatory changes. The market is segmented by type and application, with key players including Amgen, AstraZeneca, and Pfizer. Clinical trials focus on novel therapies, drug combinations, and targeted treatments, aiming to improve outcomes for renal cell carcinoma patients.
cnbc.com
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Drugmakers bet billions that targeted radiation could become the next cancer breakthrough

Drugmakers like Bristol Myers Squibb, AstraZeneca, and Eli Lilly invest billions in radiopharmaceuticals, which deliver radiation directly to tumors. These drugs, in development for various cancers, attach radioactive material to targeting molecules, sparing healthy cells. Novartis' successes with Lutathera and Pluvicto have spurred interest, but manufacturing and logistics remain complex. The market potential ranges from $5 billion to tens of billions, depending on efficacy across cancer types.
stockhouse.com
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Sanofi shipping BEYFORTUS® in US to help protect babies against RSV disease; new

Sanofi ships BEYFORTUS doses in the US to protect eligible babies against RSV, with a new FDA-approved filling line expanding manufacturing capacity. BEYFORTUS is the first long-acting monoclonal antibody for RSV prevention in newborns and infants up to 24 months.
astrazeneca-us.com
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IMFINZI® (durvalumab) plus IMJUDO® (tremelimumab-actl) demonstrated unprecedented ...

The STRIDE regimen's safety profile aligns with known medicine profiles, with no new safety signals. IMFINZI and IMJUDO are approved for advanced or unresectable HCC in multiple countries. Immune-mediated adverse reactions, including pneumonitis, colitis, hepatitis, and endocrinopathies, are noted, necessitating close monitoring and prompt management. Infusion-related reactions and complications post-HSCT are also highlighted. IMFINZI and IMJUDO are not recommended for pregnant or breastfeeding women.
biospace.com
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PatientSeek identifies a genetic signature that separates a4b7 integrin therapy responder

C4XD discovers genetic signature distinguishing a4b7 integrin therapy responders and non-responders in IBD, using PatientSeek platform for precision medicine.
newsbytesapp.com
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This drug shows promise in extending bladder cancer patients' lives

AstraZeneca's Imfinzi drug shows promise in extending bladder cancer patients' lives, potentially boosting annual revenue by $500 million if approved.
whatech.com
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Global Statins Market Insights Discussed Regarding Key Insights and Leading Countries

The statins market, valued at $22B, is projected to reach $15B by 2021, driven by cardiovascular disease prevalence, cholesterol management awareness, and statin formulation advancements. Challenges include generic competition, alternative therapies, and side effects. Opportunities lie in combination therapies and emerging markets.

TROP2-directed ADCs show promise in recurrent gynecological cancers

Platinum-based therapies are mainstay for endometrial and ovarian cancers but often recur. Antibody drug conjugates (ADCs) like Elahere and datopotamab deruxtecan (Dato-DXd) show promise, with Dato-DXd demonstrating improved outcomes in recurrent EC and OC at ESMO 2024. Dato-DXd's efficacy and safety profile, along with a convenient dosing schedule, position it as a potential preferred treatment over competitors like Merck's sacituzumab govitecan (Sac-TMT), which also shows comparable efficacy in heavily pretreated patients. Both TROP2-directed ADCs offer hope for challenging gynecological cancers.
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