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Bionomics, Inc.

🇺🇸United States
Ownership
-
Employees
-
Market Cap
$9.1M
Website

Clinical Trials

13

Active:1
Completed:10

Trial Phases

3 Phases

Phase 1:6
Phase 2:4
Phase 3:1

Drug Approvals

0

Drug Approvals

No drug approvals found

This company may not have drug approvals in our database

Clinical Trials

Distribution across different clinical trial phases (11 trials with phase data)• Click on a phase to view related trials

Phase 1
6 (54.5%)
Phase 2
4 (36.4%)
Phase 3
1 (9.1%)

Efficacy of BNC210 in Acute, As-needed Treatment of Anxiety in Social Anxiety Disorder - 1

Phase 3
Recruiting
Conditions
Social Anxiety Disorder
Interventions
Drug: 225 mg BNC210
Drug: Placebo
First Posted Date
2024-07-19
Last Posted Date
2025-04-17
Lead Sponsor
Bionomics Limited
Target Recruit Count
332
Registration Number
NCT06510504
Locations
🇺🇸

AFFIRM-1 Study Site, Austin, Texas, United States

A Phase 2 Study of BNC210 for the Acute Treatment of Social Anxiety Disorder

Phase 2
Completed
Conditions
Social Anxiety Disorder
Interventions
Drug: 225 mg BNC210
Drug: 675 mg BNC210
Drug: Placebo
First Posted Date
2022-01-14
Last Posted Date
2025-03-18
Lead Sponsor
Bionomics Limited
Target Recruit Count
151
Registration Number
NCT05193409
Locations
🇺🇸

PREVAIL Study Clinical Trial Site, Draper, Utah, United States

A Phase 2b Study of BNC210 Tablet Formulation in Adults With Post-Traumatic Stress Disorder (PTSD)

Phase 2
Completed
Conditions
Post-Traumatic Stress Disorder
Interventions
Drug: Placebo
First Posted Date
2021-07-06
Last Posted Date
2025-02-06
Lead Sponsor
Bionomics Limited
Target Recruit Count
212
Registration Number
NCT04951076
Locations
🇬🇧

ATTUNE Study Clinical Trial Site, Stockton-on-Tees, United Kingdom

🇺🇸

ATTTUNE Study Clinical Trial Site, Jacksonville, Florida, United States

A Study of BNC210 in Elderly Patients With Agitation

Phase 2
Completed
Conditions
Agitation in the Elderly
Interventions
Drug: Placebo
First Posted Date
2018-06-07
Last Posted Date
2020-07-09
Lead Sponsor
Bionomics Limited
Target Recruit Count
38
Registration Number
NCT03548194
Locations
🇦🇺

Prince of Wales Hospital, Sydney, New South Wales, Australia

🇦🇺

Modbury Hospital, Adelaide, South Australia, Australia

🇦🇺

Northern Health, Melbourne, Victoria, Australia

and more 2 locations

Phase II Study of BNC210 in PTSD

Phase 2
Completed
Conditions
Post-Traumatic Stress Disorder
Interventions
Drug: Placebo
First Posted Date
2016-10-14
Last Posted Date
2023-02-27
Lead Sponsor
Bionomics Limited
Target Recruit Count
193
Registration Number
NCT02933606
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News

Bionomics' BNC210 Shows Positive Phase 2 Results in PTSD Patients, Phase 3 Planned

Bionomics' BNC210 demonstrated statistically significant improvement in PTSD symptom severity compared to placebo at Week 12, with benefits observed as early as Week 4.

BNC210 Shows Promise in Phase IIb Trial for PTSD Treatment

A Phase IIb trial of BNC210, a novel α7 nicotinic acetylcholine receptor modulator, demonstrated significant improvement in PTSD symptom severity as early as 4 weeks.

Bionomics Advances BNC210 Phase 3 Trial for Social Anxiety Disorder and Strategic Partnership with Merck

Bionomics initiates Phase 3 trial for BNC210 in social anxiety disorder (SAD) after successful regulatory interactions and IP portfolio expansion, with data readout anticipated in Q3 2025.

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