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Immuneel Launches Qartemi, a CAR T-cell Therapy for Non-Hodgkin's Lymphoma in India

• Immuneel Therapeutics has launched Qartemi, India's first CAR T-cell therapy for treating adult B-cell Non-Hodgkin Lymphoma (B-NHL). • Qartemi is a personalized therapy that modifies a patient’s T-cells to target and eliminate cancer cells, offering hope for lasting remission. • Clinical trials in India and Spain demonstrated that Qartemi's safety and efficacy are similar to US FDA-approved CAR T-cell therapies. • Priced at approximately ₹35 to ₹50 lakh, Qartemi is significantly more affordable than similar treatments in the US.

Gene Therapy Trial for Hemophilia Shows Success, Announced by Indian Biotechnology Research and Innovation Council

• A successful gene therapy trial for hemophilia, supported by the Department of Biotechnology, was announced at the Biotechnology Research and Innovation Council (BRIC) meeting. • The trial, conducted at Christian Medical College, Vellore, has been reported in the prestigious New England Journal of Medicine. • BRIC is playing a significant role in unifying governance across 14 biotechnology institutions to foster research, innovation, and capacity building in India. • The i3c BRIC-RCB-PhD Programme was launched, enrolling 58 students to promote interdisciplinary research and hands-on training in biotechnology.

Indian Scientists Report Success with Novel Gene Therapy for Severe Hemophilia A

• A novel gene therapy developed in India has shown promising results in treating severe Hemophilia A, with a zero bleeding rate observed in treated patients. • The gene therapy uses a lentiviral vector to introduce a corrected gene into stem cells, enabling the body to produce Factor VIII autonomously. • This one-time treatment offers a potential lifelong solution, reducing the need for frequent and expensive clotting factor infusions. • The initial trial, involving five patients, suggests this therapy could be a more affordable and accessible option for Hemophilia A patients in resource-constrained settings.
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