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Latvijas Universitate

🇱🇻Latvia
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H. Pylori Screen-and-treat Study in a Population of Young Adults

Recruiting
Conditions
Gastric Cancer
H Pylori Infection
H Pylori Eradication
H-pylori
Interventions
Drug: Bismuth-based quadruple therapy
Drug: Levofloxacin-based quadruple therapy
Drug: Standard triple therapy
Drug: Levofloxacin-based triple
First Posted Date
2024-02-23
Last Posted Date
2024-03-05
Lead Sponsor
University of Latvia
Target Recruit Count
6800
Registration Number
NCT06275204
Locations
🇮🇪

Beacon Hospital, Dublin, Ireland

🇵🇱

Wroclaw Medical University, Wroclaw, Poland

🇷🇴

Iuliu Hatieganu University of Medicine and Pharmacy, Cluj-Napoca, Cluj County, Romania

and more 4 locations

Hybrid-sensor Breath Analysis for Colorectal Cancer Screening

Conditions
Polyp of Colon
Colorectal Cancer
Interventions
Device: Breath sampling for VOC detection
Other: Secondary validation study in general CRC screening settings
Procedure: Identification of specific VOCs in CRC tissue surgery material
Other: Blood sample collection
Diagnostic Test: Microbiota testing
Diagnostic Test: Colonoscopy
First Posted Date
2021-12-29
Last Posted Date
2022-02-15
Lead Sponsor
University of Latvia
Target Recruit Count
3000
Registration Number
NCT05173077
Locations
🇱🇻

University of Latvia, Riga, Latvia

Screening of Gastric Cancer Via Breath Volatile Organic Compounds by Hybrid Sensing Approach

Recruiting
Conditions
Gastric Cancer
Atrophic Gastritis
Gastric Dysplasia
H.Pylori Infection
Interventions
Device: Breath sampling for VOC detection
Procedure: Surgery material collection for VOC headspace analysis
Diagnostic Test: Upper endoscopy
Diagnostic Test: Microbiota testing
First Posted Date
2019-07-16
Last Posted Date
2021-07-26
Lead Sponsor
University of Latvia
Target Recruit Count
5000
Registration Number
NCT04022109
Locations
🇱🇻

Institute of Clinical and Preventive Medicine, University of Latvia, Riga, Latvia

🇧🇷

A.C.Camargo Cancer Center, São Paulo, Brazil

🇨🇱

Pontificia Universidad Catolica de Chile, Santiago, Chile

and more 2 locations

Surveillance of Patients With Precancerous Lesions of the Stomach

Recruiting
Conditions
Gastric Cancer
Gastric Intestinal Metaplasia
Gastric Dysplasia
Gastric Atrophy
Interventions
Procedure: Upper endoscopy with biopsies
Procedure: Plasma/serum sampling
Procedure: Biopsies for gastric microbiota
Procedure: Faecal sample acquisition
First Posted Date
2017-08-15
Last Posted Date
2018-08-21
Lead Sponsor
University of Latvia
Target Recruit Count
2000
Registration Number
NCT03250091
Locations
🇱🇻

University of Latvia, Riga, Latvia

Effects of H.Pylori Eradication on Microbiome

Phase 4
Conditions
Human Microbiome
Interventions
Other: Microbiome Diversity detection
First Posted Date
2017-07-27
Last Posted Date
2018-08-22
Lead Sponsor
University of Latvia
Target Recruit Count
900
Registration Number
NCT03231332
Locations
🇱🇻

University of Latvia, Riga, Latvia

Volatiles in Breath and Headspace Analysis - Diagnostic Markers

Conditions
Colorectal Polyp
Liver Cancer
Flu, Human
Other Infectious Diseases
Tuberculosis
Gastric Cancer
Atrophic Gastritis
Gastric Dysplasia
Pancreatitis, Chronic
Liver Cirrhosis
Interventions
Diagnostic Test: Breath sampling
Diagnostic Test: VOC detection in breath and in skin headspace
Procedure: Upper endoscopy with biopsies
Procedure: Colonoscopy with biopsies
Procedure: Whole blood/ Plasma / serum sampling
Diagnostic Test: Headspace analysis for biological material
Diagnostic Test: Faecal sampling
Procedure: Histological examination of surgical specimen
First Posted Date
2017-07-24
Last Posted Date
2018-08-21
Lead Sponsor
University of Latvia
Target Recruit Count
3000
Registration Number
NCT03228095
Locations
🇱🇻

University of Latvia, Riga, Latvia

Volatile Markers in Digestive Cancer

Completed
Conditions
Gastric Cancer
Peptic Ulcer Disease
Atrophic Gastritis
Intestinal Metaplasia
H.Pylori Infection
Normal Control
Average-risk General Population
Colorectal Cancer
Colorectal Adenoma
Interventions
Procedure: Breath sampling for volatile marker detection
Procedure: Colonoscopy with biopsies or lesion removal when required
Procedure: Upper endoscopy with biopsies
Procedure: Plasma/serum sampling
Procedure: Faecal sample acquisition
Procedure: Histological evaluation of the surgery material
First Posted Date
2015-01-06
Last Posted Date
2018-08-21
Lead Sponsor
University of Latvia
Target Recruit Count
2022
Registration Number
NCT02332213
Locations
🇱🇹

Lithuanian University of Health Sciences, Kaunas, Lithuania

🇱🇻

University of Latvia, Riga, Latvia

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