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NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE

🇺🇸United States

Country: 🇺🇸United States

Ownership: -

Employees: -

Market Cap: -

Website

Clinical Trials

Natural History Protocol for Movement Disorders

Recruiting

Conditions: Parkinson's Disease
Movement Disorder
Tremor

First Posted Date: 2022-06-10

Last Posted Date: 2025-03-26

Lead Sponsor: National Institute of Neurological Disorders and Stroke (NINDS)

Target Recruit Count: 4000

Registration Number: NCT05413291

Locations: 🇺🇸
National Institutes of Health Clinical Center, Bethesda, Maryland, United States

NIH Investigative Deep Phenotyping Study of Gulf War Veteran Health (Project NIH IN-DEPTH)

Recruiting

Conditions: Gulf War Illness

First Posted Date: 2022-05-17

Last Posted Date: 2025-07-04

Lead Sponsor: National Institute of Neurological Disorders and Stroke (NINDS)

Target Recruit Count: 85

Registration Number: NCT05375812

Locations: 🇺🇸
National Institutes of Health Clinical Center, Bethesda, Maryland, United States

Immunotherapy for Neurological Post-Acute Sequelae of SARS-CoV-2

Phase 2

Conditions: Systemic Inflammation
Microvascular Thrombosis
Neuroinflammation

Interventions: Drug: IV immunoglobulin
Drug: IV normal saline

First Posted Date: 2022-04-28

Last Posted Date: 2025-04-01

Lead Sponsor: National Institute of Neurological Disorders and Stroke (NINDS)

Target Recruit Count: 45

Registration Number: NCT05350774

Locations: 🇺🇸
National Institutes of Health Clinical Center, Bethesda, Maryland, United States

Investigational Use of Neuromuscular Ultrasound

Recruiting

Conditions: Normal Physiology
Peripheral Neuropathy
Motor Neuron Disorder
Muscular Dystrophy

First Posted Date: 2022-02-14

Last Posted Date: 2024-12-27

Lead Sponsor: National Institute of Neurological Disorders and Stroke (NINDS)

Target Recruit Count: 150

Registration Number: NCT05237973

Locations: 🇺🇸
National Institutes of Health Clinical Center, Bethesda, Maryland, United States

Non-invasive Intermittent Theta Burst Stimulation of the Dorsolateral Prefrontal Cortex in Functional Movement Disorders

Phase 2

Active, not recruiting

Conditions: Functional Movement Disorder

First Posted Date: 2021-12-13

Last Posted Date: 2025-06-03

Lead Sponsor: National Institute of Neurological Disorders and Stroke (NINDS)

Target Recruit Count: 21

Registration Number: NCT05155059

Locations: 🇺🇸
National Institutes of Health Clinical Center, Bethesda, Maryland, United States

Data Collection of Standard Care of Patients in the EMG Section

Recruiting

Conditions: Neuropathy
Muscle Disorders
Dysautonomia

First Posted Date: 2021-09-13

Last Posted Date: 2024-12-20

Lead Sponsor: National Institute of Neurological Disorders and Stroke (NINDS)

Target Recruit Count: 200

Registration Number: NCT05041387

Locations: 🇺🇸
National Institutes of Health Clinical Center, Bethesda, Maryland, United States

Clinical, Molecular and Imaging Biomarkers in Spinal and Bulbar Muscular Atrophy (SBMA)

Recruiting

Conditions: Spinal and Bulbar Muscular Atrophy
Kennedys Disease
Motor Neuron Disease

First Posted Date: 2021-06-30

Last Posted Date: 2025-07-02

Lead Sponsor: National Institute of Neurological Disorders and Stroke (NINDS)

Target Recruit Count: 70

Registration Number: NCT04944940

Locations: 🇺🇸
National Institutes of Health Clinical Center, Bethesda, Maryland, United States

Teriflunomide in HTLV-1 Associated Myelopathy/Tropical Spastic Paraparesis

Phase 1

Recruiting

Conditions: HAM/TSP

Interventions: Drug: Teriflunomide

First Posted Date: 2021-03-16

Last Posted Date: 2025-07-09

Lead Sponsor: National Institute of Neurological Disorders and Stroke (NINDS)

Target Recruit Count: 24

Registration Number: NCT04799288

Locations: 🇺🇸
National Institutes of Health Clinical Center, Bethesda, Maryland, United States

NT-I7, a Long-Acting Recombinant IL-7 Molecule, as an Immune Reconstitution Strategy for Lymphopenia in Patients With Progressive Multifocal Leukoencephalopathy

Early Phase 1

Recruiting

Conditions: Progressive Multifocal Leukoencephalopathy

Interventions: Drug: NT-I7

First Posted Date: 2021-03-04

Last Posted Date: 2025-06-18

Lead Sponsor: National Institute of Neurological Disorders and Stroke (NINDS)

Target Recruit Count: 18

Registration Number: NCT04781309

Locations: 🇺🇸
National Institutes of Health Clinical Center, Bethesda, Maryland, United States

Tolebrutinib, a Brain-penetrant Bruton's Tyrosine Kinase Inhibitor, for the Modulation of Chronically Inflamed White Matter Lesions in Multiple Sclerosis

Phase 2

Active, not recruiting

Conditions: Multiple Sclerosis

Interventions: Drug: tolebrutinib 60mg
Drug: tolebrutinib 120mg

First Posted Date: 2021-02-08

Last Posted Date: 2024-08-13

Lead Sponsor: National Institute of Neurological Disorders and Stroke (NINDS)

Target Recruit Count: 12

Registration Number: NCT04742400

Locations: 🇺🇸
National Institutes of Health Clinical Center, Bethesda, Maryland, United States

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