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Dynavax Technologies

🇺🇸United States
Ownership
-
Employees
408
Market Cap
$1.4B
Website
Introduction

Dynavax Technologies Corp. operates as a biopharmaceutical company, which engages in the discovery, development, and commercialization of novel vaccines and immuno-oncology therapeutics. Its product includes HEPLISAV-B, which prevents infection caused by all known subtypes of hepatitis B virus in adults 18 years of age and older. The company was founded by Lawrence M. Lichtenstein, Dennis A. Carson, and Eyal Raz on August 29, 1996 and is headquartered in Emeryville, CA.

Clinical Trials

31

Active:6
Completed:18

Trial Phases

4 Phases

Phase 1:14
Phase 2:5
Phase 3:5
+1 more phases

Drug Approvals

0

Drug Approvals

No drug approvals found

This company may not have drug approvals in our database

Clinical Trials

Distribution across different clinical trial phases (25 trials with phase data)• Click on a phase to view related trials

Phase 1
14 (56.0%)
Phase 2
5 (20.0%)
Phase 3
5 (20.0%)
Not Applicable
1 (4.0%)

Safety and Immunogenicity of an Investigational Herpes Zoster Vaccine (Z-1018) Compared to Shingrix® in Healthy Adults

Phase 1
Recruiting
Conditions
Shingles
Vaccine-Preventable Diseases
Herpes Zoster
First Posted Date
2024-08-26
Last Posted Date
2024-08-26
Lead Sponsor
Dynavax Technologies Corporation
Target Recruit Count
440
Registration Number
NCT06569823
Locations
🇦🇺

Northern Beaches Clinical Research, Brookvale, New South Wales, Australia

Trial of the Immunogenicity, Safety, and Tolerability of rF1V Vaccine With CpG 1018® Adjuvant Compared With rF1V Vaccine in Adults 18 to 55 Years of Age

Phase 2
Completed
Conditions
Plague
Vaccine-Preventable Diseases
Plague, Pneumonic
First Posted Date
2022-08-18
Last Posted Date
2024-05-23
Lead Sponsor
Dynavax Technologies Corporation
Target Recruit Count
200
Registration Number
NCT05506969
Locations
🇺🇸

Optimal Research Alabama, Huntsville, Alabama, United States

🇺🇸

Optimal Research California, San Diego, California, United States

🇺🇸

Optimal Research Florida, Melbourne, Florida, United States

and more 3 locations

Trial to Evaluate the Safety, Tolerability, and Immunogenicity of an Investigational Herpes Zoster Vaccine (Z-1018) Compared to Shingrix® in Healthy Adult Volunteers

Phase 1
Completed
Conditions
Shingles
Vaccine-Preventable Diseases
Herpes Zoster
First Posted Date
2022-02-18
Last Posted Date
2022-11-07
Lead Sponsor
Dynavax Technologies Corporation
Target Recruit Count
150
Registration Number
NCT05245838
Locations
🇦🇺

Paratus Clinical Research Western Sydney, Blacktown, New South Wales, Australia

🇦🇺

Northern Beaches Clinical Research, Brookvale, New South Wales, Australia

🇦🇺

Paratus Clinical Research Central Coast, Kanwal, New South Wales, Australia

and more 1 locations

HEPLISAV-B® in Adults With End-Stage Renal Disease (ESRD) Undergoing Hemodialysis

Phase 1
Completed
Conditions
End Stage Renal Disease on Hemodialysis (Diagnosis)
Interventions
First Posted Date
2019-05-02
Last Posted Date
2024-08-09
Lead Sponsor
Dynavax Technologies Corporation
Target Recruit Count
119
Registration Number
NCT03934736
Locations
🇺🇸

DaVita Clinical Research or Affiliate, Milwaukee, Wisconsin, United States

DV2-HBV-27: Observational Pregnancy Registry

Active, not recruiting
Conditions
Pregnant
First Posted Date
2018-09-10
Last Posted Date
2023-09-18
Lead Sponsor
Dynavax Technologies Corporation
Target Recruit Count
300
Registration Number
NCT03664648
Locations
🇺🇸

PPD Registry Office, Recruiting Nationwide, Wilmington, North Carolina, United States

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News

Sonoma Biotherapeutics Strengthens Leadership Team with Appointment of Rajesh Krishnan as Chief Technical Officer

• Sonoma Biotherapeutics has appointed Rajesh Krishnan, Ph.D., as Chief Technical Officer to advance their engineered regulatory T cell (Treg) therapies for autoimmune and inflammatory diseases. • Dr. Krishnan brings over 25 years of industry experience in process development and manufacturing, most recently serving as CTO and CSO at Oncternal Therapeutics with previous leadership roles at Dynavax, Gilead, Merck, Amgen, and Pfizer. • The strategic appointment comes at a crucial time for the clinical-stage biotech company as they continue developing novel treatments aimed at restoring immune system balance through proprietary Treg cell therapy platforms.

Dynavax Reports Strong Growth with HEPLISAV-B Revenue Up 26% in 2024, Advances Pipeline Programs

HEPLISAV-B achieved record net product revenue of $268.4 million in 2024, representing a 26% year-over-year growth, with market share reaching 44% in the U.S. hepatitis B vaccine market.

Goldman Sachs Downgrades Dynavax on Competitive Pressures in Shingles and Hepatitis B Markets

Goldman Sachs has downgraded Dynavax Technologies to Sell from Neutral, reducing price target to $12 amid growing competition in the shingles vaccine market and uncertainties around Z-1018 program.

HepB-CpG Vaccine Shows Superior Response in HIV Patients Non-Responsive to Traditional Hepatitis B Vaccine

A phase 3 trial showed HepB-CpG vaccine achieved superior seroprotection in HIV patients who did not respond to prior HepB-alum vaccination.

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