Umc Utrecht

AACR focuses on cancer prevention and early detection, with Kornelia Polyak's pioneering research highlighting the importance of early-stage disease study. The AACR established the Cancer Prevention Working Group in 2021 to support innovative science and public education. Liquid biopsies and multi-cancer early detection (MCED) tests are being developed to improve screening. The NCI's National Cancer Plan and President Biden's proclamation of April 2024 as National Cancer Prevention and Early Detection Month emphasize the urgency of these efforts. Researchers are exploring liquid biopsies, MCED, cancer interception, and population science to advance early detection and prevention strategies.

ProJenX, Inc. forms Clinical Advisory Board (ClAB) with experts in ALS and neurodegenerative diseases to guide clinical development of prosetin, a novel brain-penetrant MAP4K inhibitor. Prosetin is being evaluated in Study PRO-101, a Phase 1 trial assessing safety and tolerability in healthy volunteers and ALS participants, with positive early results.