Vertex, Inc. engages in the provision of tax compliance software solutions. The firm offers comprehensive solutions that automate end-to-end indirect tax processes for enterprises and mid-market companies with complex tax transactions. Its software enables tax determination, data management, compliance and reporting, and document management. The company was founded by Ray Westphal and Antoinette Westphal in 1978 and is headquartered in King of Prussia, PA.
Royalty Pharma shareholders have overwhelmingly approved the acquisition of its external manager, with 99.9% voting in favor at the company's 2025 Annual General Meeting.
Takeda Pharmaceutical is positioning three upcoming late-stage clinical trial readouts as a strategic "inflection point" to offset revenue losses from Vyvanse's generic competition.
Calidi Biotherapeutics has appointed Eric Poma, Ph.D., as its new CEO effective April 22, 2025, succeeding Allan Camaisa who will continue to serve on the company's Board of Directors.
Orphan drug sales reached $168 billion globally in 2023, with growth expected to moderate to just under 10% annually through 2028, according to Evaluate's latest report.
Lexicon Pharmaceuticals' non-opioid painkiller pilavapadin failed to achieve statistical significance versus placebo in Phase IIb RELIEF-DPN-1 trial for diabetic neuropathy pain.
NHS England approves Casgevy, a gene-editing therapy, for treating severe sickle cell disease in eligible patients aged 12 and over.
The FDA approved Alhemo (concizumab) from Novo Nordisk for hemophilia A and B with inhibitors, offering a once-daily subcutaneous option.
GSK's cancer drug combination achieved primary endpoints in ovarian cancer trials, marking a significant advancement in treatment options, though some secondary goals were unmet.
Eli Lilly's shares surged by 37% YTD, driven by the success of Zepbound for weight loss and advancements in its Alzheimer's treatment, Kisunla.
Vertex Pharmaceuticals increased its full-year product revenue guidance to $10.8-$10.9 billion, driven by strong performance of TRIKAFTA/KAFTRIO and anticipated CASGEVY launches.