• A real-world study among older US veterans showed RSV vaccines are highly effective against infection, ED/UC visits, and hospitalization.
• The study found vaccine effectiveness of 78% against RSV infection, 79% against ED/UC visits, and 80% against hospital admissions.
• Vaccine effectiveness against RSV infection was 72.3% in veterans aged 80 years and older and 71.6% in those with weakened immune systems.
• The findings support current recommendations for RSV vaccination in adults aged 60 years and older, with updated CDC guidance for the 2024-2025 season.